Results 111 to 120 of about 4,591 (213)
Noggin null allele mice exhibit a microform of holoprosencephaly [PDF]
, 2017 Holoprosencephaly (HPE) is a heterogeneous craniofacial and neural developmental anomaly characterized in its most severe form by the failure of the forebrain to divide.
Alakurtti, Kirsi +9 more
core
Pax9 and Jagged1 act downstream of Gli3 in vertebrate limb development
Mechanisms of Development, 2005 From early in limb development the transcription factor Gli3 acts to define boundaries of gene expression along the anterior-posterior (AP) axis, establishing asymmetric patterns required to provide positional information. As limb development proceeds, posterior mesenchyme expression of Sonic hedgehog (Shh) regulates Gli3 transcription and post ...
McGlinn, Edwina +11 more
openaire +3 more sources
Genetic architecture of craniofacial morphogenesis: roles of PAX3, PAX7, and PAX9
Frontiers in Cell and Developmental BiologyCraniofacial morphogenesis is a highly coordinated developmental process governed by complex genetic and molecular interactions. Among these, the PAX family of transcription factors plays a pivotal role in the regulation of neural crest specification ...
Kun Wang +12 more
doaj +1 more source
Defective Msx1 Nuclear Translocation Underlies Severe Oligodontia
International Dental JournalAim or purpose: This study aimed to elucidate the mechanism by which MSX1 variants contribute to nonsyndromic tooth agenesis (NSTA) and determine how variant domains correlate with tooth loss severity.
Jing Sun, Chen Yiqi, Zhang Caiqi
doaj +1 more source
Multiple dens invaginatus, mulberry molar and conical teeth : case report and genetic considerations [PDF]
, 2009 Dens in dente, also known as dens invaginatus and dilated compound odontoma, is a malformation that can occur on primary, permanent, or supernumerary teeth that is characterized by a deep invagination of the surface of a crown or root covered with ...
Naranjo Corona, Rosa I. +3 more
core
Pakistan Armed Forces Medical Journal, 2018 Objective: To identify the phenotype and genotype of hypodontia for a Pakistani family with hypodontia and to map the genes locus responsible for this disease. Study Design: Descriptive study.
Muhammad Nawaz +4 more
doaj
An inwardly rectifying K+ channel is required for patterning. [PDF]
, 2012 Mutations that disrupt function of the human inwardly rectifying potassium channel KIR2.1 are associated with the craniofacial and digital defects of Andersen-Tawil Syndrome, but the contribution of Kir channels to development is undefined.
Bates, Emily +6 more
core
Primate phylogeny: molecular evidence for a pongid clade excluding humans and a prosimian clade containing tarsiers [PDF]
, 2009 Interpretations of molecular data by the modern evolution theory are often sharply inconsistent with paleontological results. This is to be expected since the theory is only true for microevolution and yet fossil records are mostly about macroevolution.
Shi Huang
core +1 more source