Results 91 to 100 of about 3,069 (190)

Defective Msx1 Nuclear Translocation Underlies Severe Oligodontia

International Dental Journal
Aim or purpose: This study aimed to elucidate the mechanism by which MSX1 variants contribute to nonsyndromic tooth agenesis (NSTA) and determine how variant domains correlate with tooth loss severity.
Jing Sun, Chen Yiqi, Zhang Caiqi
doaj   +1 more source

Characterization and developmental expression of Pax9, a paired-box-containing gene related to Pax1.

, 1995
peer reviewedPax9, a recently identified mouse paired-box-containing gene, is highly homologous to Pax1 and belongs to the same subfamily as Pax1, Hup48, PAX9, and pox meso.
Koseki, H., BALLING, Rudi, Neubüser, Annette, Koseki, Haruhiko, Neubuser, A.   +4 more
core   +1 more source

Novel PAX9 Mutations Cause Non-syndromic Tooth Agenesis [PDF]

, 2014
PAX9 is a transcription factor expressed in the tooth mesenchyme during tooth morphogenesis. In Pax9-null mice, tooth development is arrested at the bud stage.
80380046, マスダ, キヨシ, 堀内, 信也, 174876/profile-ja.html, ヤスエ, アキヒロ, 209760/profile-ja.html, Mitsui Akagi, Silvia Naomi, Tanaka, Eiji, 272, 70263861, 増田, 清士, 1695, Yasue, Akihiro, 458, 田中, 栄二, ワタナベ, ケイイチロウ, ミツイ アカギ, シルビア ナオミ, 井本, 逸勢, Masuda, Kiyoshi, Imoto, Issei, 00457318, イモト, イッセイ, ホリウチ, シンヤ, 60398/profile-ja.html, 30258610, 40273693, 1252, 20634554, 泰江, 章博, 444, 323, 渡邉, 佳一郎, タナカ, エイジ, Watanabe, Keiichiro, Horiuchi, Shinya   +34 more
core  

Nine Novel PAX9 Mutations and a Distinct Tooth Agenesis Genotype-Phenotype

, 2017
Tooth agenesis is one of the most common developmental anomalies affecting function and esthetics. The paired-domain transcription factor, Pax9, is critical for patterning and morphogenesis of tooth and taste buds. Mutations of PAX9 have been identified
H. Zhang, B. Bai, X. Zhang, S.A. Frazier-Bowers, L. Zeng, H. Liu, Y.-X. Wang, N. Zhao, S.-W. Wong, H. Feng, M.Z. Miao, Y. Liu, Y. Wang, D. Han   +13 more
core   +1 more source

PAX9 regulates squamous cell differentiation and carcinogenesis in the oro-esophageal epithelium [PDF]

PAX9 is a transcription factor of the PAX family characterized by a DNA-binding paired domain. Previous studies have suggested a potential role of PAX9 in squamous cell differentiation and carcinogenesis of the oro-esophageal epithelium.
Huang C, Peters H, Kist R, Chen H, Garman K, Sun Z, Xiong Z, Liu Y, Zhang YL, Chen X, Ren S, Odera JO, Chen T   +12 more
core   +3 more sources

MSX1, PAX9, and TGFA contribute to tooth agenesis in humans.

, 2004
In this study, we sought to determine the association between tooth agenesis and DNA sequence variation in the genes MSX1 and PAX9 in an ethnically diverse human population.
Meira, R, Modesto, A, Murray, J C, Vieira, A R   +3 more
core  

Unravelling the Molecular Connection Between Pax9 and Autophagy To Regulate Oral Carcinogenesis

, 2022
PAired boX 9 (PAX9) gene belong to the PAX family, which encodes a family of metazoan transcription factors documented by a conserved DNA binding paired domain 128-amino- acids, critically essential for physiology and development.
Bhol, Chandra Sekhar
core  

PAX9 Gene [PDF]

, 2020
openaire   +1 more source

PAX9 GENE POLYMORPHISMS AND MISSING TEETH

, 2013
It was shown in both mouse and human tooth development that PAX9 and MSX1 are the most important genes regulating progression through early stages of tooth development.
Balghonaim, Abir, Liu, K., Leach, J., Petrovska, M., Tolarova, Maria M., Abolfazlian, A., Chin, A., Lee, V., Zhu, J., Tarifard, A., Tolar, Mirek, Christie, M., Berdichevsky, H., Heetland, K.   +13 more
core  

PAX9 wt Allele [PDF]

, 2020
openaire   +1 more source