Genotyping analysis of the Pax9 Gene in patients with maxillary canine impaction [version 1; peer review: 2 approved] [PDF]
F1000Research, 2019 Background: Paired-box gene 9 (PAX9) mutation is potentially associated with impaction in some patient populations. Here, we analyzed the relationship between PAX9 polymorphism and the occurrence of maxillary canine impaction.
Evy Eida Vitria +3 more
doaj +3 more sources
Association between PAX9 or MSX1 gene polymorphism and tooth agenesis risk: A meta-analysis [PDF]
Open Life SciencesTooth loss represents the most prevalent form of dental agenesis. Anterior tooth loss primarily impacts aesthetics and psychological well-being, whereas posterior tooth loss influences bone growth patterns and masticatory function.
Zhong Xiaoyi +4 more
doaj +3 more sources
Kaohsiung Journal of Medical Sciences, 2022 To investigate the effect of PAX9 on the progression of cervical cancer (CC). PAX9 expression was quantified in CC tissues and adjacent normal tissues, as well as human CC cell lines and human cervical epithelial cells (HCerEpiC).
Jie Liu +3 more
doaj +3 more sources
Genetic association between Class II division 1 and division 2 malocclusions with PAX9 (rs8004560) gene polymorphism in a tertiary care hospital [PDF]
Dental Press Journal of OrthodonticsObjective: To assess whether there is any difference in the genetic association between Class II division 1 (div. 1) and division 2 (div. 2) malocclusions using PAX9 (rs8004560) gene single nucleotide polymorphism (SNP).
Monika SHUKLA +9 more
doaj +3 more sources
Genetic architecture of craniofacial morphogenesis: roles of PAX3, PAX7, and PAX9 [PDF]
Frontiers in Cell and Developmental BiologyCraniofacial morphogenesis is a highly coordinated developmental process governed by complex genetic and molecular interactions. Among these, the PAX family of transcription factors plays a pivotal role in the regulation of neural crest specification ...
Kun Wang +12 more
doaj +2 more sources
Journal of Applied Oral Science, 2007 PURPOSE: Hypodontia is the congenital absence of one or more (up to six) permanent and/or deciduous teeth, being one of the most common alterations of the human dentition.
Fabio José Bianch +4 more
doaj +2 more sources
The Evolution of Gene Sequencing Technologies: Unveiling Genetic Architecture of Nonsyndromic Orofacial Clefts. [PDF]
Genet Res (Camb)Nonsyndromic orofacial clefts (NSOC) are common congenital craniofacial developmental defects. Current evidence suggests that genetic factors, environmental exposures, and their interactions jointly contribute to the development of the disease. Owing to the high heritability of NSOC, identifying susceptibility genes and loci is a central focus of ...
Zhao H, Zhang S, Zhu H, Jia Z.
europepmc +2 more sources
Integrated Genetic Networks and Epigenetic Regulation inTooth Development and Maturation [PDF]
CellsTooth development or odontogenesis is a complex morphogenetic process that requires tightly regulated interactions between the oral epithelium and mesenchyme of neural crest origin.
Dong-Joon Lee +2 more
doaj +2 more sources
Single cell spatial transcriptomics links Wnt signaling disruption to extracellular matrix development in a cleft palate model [PDF]
Scientific ReportsDespite advances in understanding the morphological disruptions that lead to defects in palate formation, the precise perturbations within the signaling microenvironment of palatal clefts remain poorly understood.
Jeremie Oliver Piña +8 more
doaj +2 more sources
Expression Characteristics of PAX7 and Its Prognostic Correlation in Breast Cancer. [PDF]
Breast JObjective To conduct a thorough analysis of public databases to investigate the expression patterns of the PAX7 gene in breast cancer. Methods We gathered gene expression data, clinical details, immunohistochemistry images, and genomic information from breast cancer patients through various public databases, such as TCGA, THPA, GEPIA, and cBioPortal ...
Silafu B, Huang J, Aizezi X.
europepmc +2 more sources