Results 11 to 20 of about 7,348,517 (171)
Identification of a nonsense mutation in the PAX9 gene in molar oligodontia [PDF]
European Journal of Human Genetics, 2001 Development of dentition is controlled by numerous genes, as has been shown by experimental animal studies and mutations that have been identified by genetic studies in man. Here we report a nonsense mutation in the PAX9 gene that is associated with molar tooth agenesis in a Finnish family. The A340T transversion creates a stop codon at lysine 114, and
Pekka Nieminen +2 more
exaly +4 more sources
South Asian Research Journal of Oral and Dental Sciences, 2021 Background: Development of dentition is controlled by numerous genes, proven by experimental animal studies and mutations that have been identified by genetic studies in man.
Pranav Vaid +5 more
semanticscholar +2 more sources
Screening for MSX1 and PAX9 gene variants among hypodontia patients in the Jordanian population.
Cellular and Molecular BiologyThis study aimed to sequence the PAX9 and MSX1 genes in a group of Jordanian patients diagnosed with non-syndromic hypodontia. The study also examined whether the identified genetic variants in these key odontogenic genes could be used to assess ...
Areej Quran +4 more
semanticscholar +3 more sources
Genetic Analysis of the PAX9 Gene Polymorphism in the Etiology of Impacted Maxillary Canines
Saudi Journal of Oral and Dental ResearchBackground: Maxillary canines are the second most frequently impacted teeth after third molars, with a prevalence of approximately 2% in the general population.
Dr Sabeena +5 more
semanticscholar +2 more sources
The application of clinical genetics, 2018 Background The congenital absence of one or few teeth, hypodontia, is considered one of the utmost dental ageneses in human beings. Several genes have been shown to be involved in the development of hypodontia such as paired box gene 9 (PAX9).
Ahmed Abu-siniyeh, O. Khabour, A. Owais
semanticscholar +3 more sources
Pakistan Armed Forces Medical Journal, 2018 Objective: To identify the phenotype and genotype of hypodontia for a Pakistani family with hypodontia and to map the genes locus responsible for this disease. Study Design: Descriptive study.
Muhammad Nawaz +4 more
doaj +5 more sources
Stepwise differentiation of airway epithelial cells from human tonsil-derived mesenchymal stem cells [PDF]
Stem Cell Research & TherapyBackground Airway defects, often resulting from tumor resection, trauma, or infection, pose significant treatment challenges owing to the intricate, multilayered structure of the airway.
Ha Yeong Kim +3 more
doaj +2 more sources
Detection of a rare AXIN2 variant in an Iranian family with hypodontia and oligodontia [PDF]
Journal of Dental Research, Dental Clinics, Dental Prospects, 2022 Background. Hypodontia, or the absence of one or more teeth during tooth formation, is a highly prevalent dental anomaly. Nevertheless, the main causes are still unknown.
Shiva Safari +5 more
doaj +1 more source
Reduction of Pax9 gene dosage in an allelic series of mouse mutants causes hypodontia and oligodontia. [PDF]
Human Molecular Genetics, 2005 Missing teeth (hypodontia and oligodontia) are a common developmental abnormality in humans and heterozygous mutations of PAX9 have recently been shown to underlie a number of familial, non-syndromic cases. Whereas PAX9 haploinsufficiency has been suggested as the underlying genetic mechanism, it is not known how this affects tooth development. Here we
R. Kist +6 more
semanticscholar +4 more sources