Results 71 to 80 of about 2,193 (172)

Association between polymorphism in the promoter region (G/C-915) of PAX9 gene and third molar agenesis

open access: yesJournal of Applied Oral Science, 2007
PURPOSE: Hypodontia is the congenital absence of one or more (up to six) permanent and/or deciduous teeth, being one of the most common alterations of the human dentition.
Fabio José Bianch   +4 more
doaj   +1 more source

The role of PAX9 promoter gene polymorphisms in causing hypodontia: a study in the Jordanian population

open access: yesThe Application of Clinical Genetics, 2018
Ahmed Abu-Siniyeh,1 Omar F Khabour,1 Arwa I Owais2 1Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, Jordan University of Science and Technology, Irbid, Jordan; 2Department of Applied Dental Sciences, Faculty of Applied ...
Abu-Siniyeh A, Khabour OF, Owais AI
doaj  

Expression of Odontogenic Genes in Human Bone Marrow Mesenchymal Stem Cells [PDF]

open access: yesCell Journal, 2013
Objective: Tooth loss is a common problem and since current tooth replacement methods cannot counter balance with biological tooth structures, regenerating natural tooth structures has become an ideal goal.
Seyedeh Sara Bagheri   +4 more
doaj  

Dental agenesis: review of the literature and report of two cases

open access: yesRevista Facultad de Odontología Universidad de Antioquia, 2006
Tooth agenesis is the most common anomaly of craniofacial development. The purpose of this report is to present a brief review of literature about tooth agenesis, which includes: terminology, etiology, prevalence, associated syndromes and dental ...
Luz Ángela Arboleda-A.   +8 more
doaj  

Pax9 and Jagged1 act downstream of Gli3 in vertebrate limb development

open access: yesMechanisms of Development, 2005
From early in limb development the transcription factor Gli3 acts to define boundaries of gene expression along the anterior-posterior (AP) axis, establishing asymmetric patterns required to provide positional information. As limb development proceeds, posterior mesenchyme expression of Sonic hedgehog (Shh) regulates Gli3 transcription and post ...
McGlinn, Edwina   +11 more
openaire   +5 more sources

The role of Msx1 and Pax9 in pathogenetic mechanisms of tooth agenesis

open access: yesDental Journal, 2009
Background: Tooth agenesis is one of the most common developmental anomalies in human, which one or a few teeth are absent because they have never formed, may cause cosmetic or occlusal harm, while severe agenesis which are relatively rare require ...
Yani Corvianindya Rahayu, dyah Setyorini
doaj   +1 more source

The presence and distribution of various genes in postnatal CLP-affected palatine tissue

open access: yesMaxillofacial Plastic and Reconstructive Surgery
Background Worldwide cleft lip with or without a cleft palate (CL/P) is the most common craniofacial birth defect. Apart from changes in facial appearance, additionally affected individuals often suffer from various associated comorbidities requiring ...
Jana Goida, Mara Pilmane
doaj   +1 more source

A novel 14q13.1–21.1 deletion identified by CNV-Seq in a patient with brain-lung-thyroid syndrome, tooth agenesis and immunodeficiency

open access: yesMolecular Cytogenetics, 2019
Background Chromosome 14q11-q22 deletion syndrome (OMIM 613457) is a rare genomic disorder. The phenotype heterogeneity depends on the deletion size, breakpoints and genes deleted. Critical genes like FOXG1, NKX2–1, PAX9 were identified.
Xuyun Hu   +7 more
doaj   +1 more source

Defective Msx1 Nuclear Translocation Underlies Severe Oligodontia

open access: yesInternational Dental Journal
Aim or purpose: This study aimed to elucidate the mechanism by which MSX1 variants contribute to nonsyndromic tooth agenesis (NSTA) and determine how variant domains correlate with tooth loss severity.
Jing Sun, Chen Yiqi, Zhang Caiqi
doaj   +1 more source

Novel PAX9 mutation in a family with oligodontia

open access: yes, 2015
Introduction: Oligodontia is defined as the developmental absence of more than six permanent teeth, not including third molars. Mutations in Muscle segment homeobox 1 (MSX1) and Paired box 9 (PAX9) are associated mainly with the absence of premolar and molar teeth respectively. The reported prevalence of oligodontia is 0.08-0.16 %. Methods: A survey of
Daw, Eiman Mohammed   +4 more
openaire   +1 more source

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