Results 51 to 60 of about 4,591 (213)
Loss, persistence and reversal of phenotypic traits
Biological Reviews, EarlyView.ABSTRACT The irreversibility of complex trait loss has long been a tenet of evolutionary biology. However, this idea is increasingly at odds with the numerous documented exceptions across the Tree of Life. We synthesise this growing body of evidence across a diverse array of taxa and traits, exploring the evolutionary conditions that enable ...
Giobbe Forni +4 more
wiley +1 more source
Genes Linked with Orthodontic Issues and the Knowledge Gaps in This Association
Philippine Journal of Obstetrics and Gynecology, 2023 Orthodontics is the study of malpositioned teeth and jaws. Some commonly found orthodontic issues are malocclusions, mandibular prognathism, retrognathism, and facial asymmetry. These issues are associated with several genetic factors.
Abdulaziz Mohammed Alshahrani
doaj +1 more source
Foghiányokat kísérő egyszerű nukleotid polimorfizmusok hypodontiában = Single nucleotide polymorphisms in hypodontia [PDF]
, 2013 Komplex megközelítéssel tanulmányoztuk a fogcsírahiányban feltehetőleg résztvevő több egyszerű nukleotid polimorfizmust (SNP) a magyar populációban.
Bánóczy, Jolán +10 more
core
Genomic characterization of Gli-activator targets in sonic hedgehog-mediated neural patterning [PDF]
, 2007 Sonic hedgehog (Shh) acts as a morphogen to mediate the specification of distinct cell identities in the ventral neural tube through a Gli-mediated (Gli1-3) transcriptional network.
Davidson, Eric H. +9 more
core +2 more sources
iNew Medicine, EarlyView.ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid +4 more
wiley +1 more source
Novel PAX9 Mutations Causing Isolated Oligodontia
Journal of Personalized MedicineHypodontia, i.e., missing one or more teeth, is a relatively common human disease; however, oligodontia, i.e., missing six or more teeth, excluding the third molars, is a rare congenital disorder. Many genes have been shown to cause oligodontia in non-syndromic or syndromic conditions.
Ye Ji Lee +4 more
openaire +2 more sources
Compartmentalised expression of in epithelial somites is required for the formation of intervertebral joints [PDF]
, 2007 Expression of the mouse Delta-like 1 (Dll1) gene in the presomitic mesoderm and in the caudal halves of somites of the developing embryo is required for the formation of epithelial somites and for the maintenance of caudal somite identity, respectively ...
Ingeborg Teppner +4 more
core +1 more source
Light‐Inducible Activation of FGFR3 Facilitates Chondrocyte Maturation
Cell Proliferation, EarlyView.Light‐inducible activation of FGFR3 induced robust activation of MAPK signaling, promoting proliferation and collagen depositon in induced chondrocytes and prevent the degeneration of osteoarthritic chondrocytes.
Mengze Sun +5 more
wiley +1 more source
Functional Screenings Identify Regulatory Variants Associated with Breast Cancer Susceptibility
Current Issues in Molecular Biology, 2021 Genome-wide association studies (GWAS) have identified more than 2000 single nucleotide polymorphisms (SNPs) associated with breast cancer susceptibility, most of which are located in the non-coding region.
Naixia Ren +5 more
doaj +1 more source
Modulation of social behavior by the agouti pigmentation gene [PDF]
, 2014 Agouti is a secreted neuropeptide that acts as an endogenous antagonist of melanocortin receptors. Mice and rats lacking agouti (called non-agouti) have dark fur due to a disinhibition of melanocortin signaling and pigment deposition in the hair follicle.
Carola V +5 more
core +1 more source