Results 31 to 40 of about 2,757 (201)

Genetic variation among major human geographic groups supports a peculiar evolutionary trend in PAX9. [PDF]

PLoS ONE, 2011
A total of 172 persons from nine South Amerindian, three African and one Eskimo populations were studied in relation to the Paired box gene 9 (PAX9) exon 3 (138 base pairs) as well as its 5'and 3'flanking intronic segments (232 bp and 220 bp ...
Vanessa R Paixão-Côrtes, Diogo Meyer, Tiago V Pereira, Stéphane Mazières, Jacques Elion, Rajagopal Krishnamoorthy, Marco A Zago, Wilson A Silva, Francisco M Salzano, Maria Cátira Bortolini   +9 more
doaj   +1 more source

PAX9 polymorphism and susceptibility to sporadic non-syndromic severe anodontia: a case-control study in southwest China

Journal of Applied Oral Science, 2013
Our research aimed to look into the clinical traits and genetic mutations in sporadic non-syndromic anodontia and to gain insight into the role of mutations of PAX9, MSX1, AXIN2 and EDA in anodontia phenotypes, especially for the PAX9.
Jing WANG, Yuanzhi XU, Jing CHEN, Feiyu WANG, Renhuan HUANG, Songtao WU, Linjing SHU, Jingyi QIU, Zhi YANG, Junjie XUE, Raorao WANG, Jilin ZHAO, Wenli LAI   +12 more
doaj   +1 more source

A novel nonsense mutation in PAX9 is associated with sporadic hypodontia [PDF]

Mutagenesis, 2011
The most important events during the regulation of tooth development were inductive interactions between the epithelial and mesenchymal tissues. The expression of Pax9 had been shown to specifically mark the mesenchymal regions at the prospective sites of all teeth prior to any morphological manifestations.
Junxia, Zhu, Xiang, Yang, Chenying, Zhang, Lihong, Ge, Shuguo, Zheng   +4 more
openaire   +2 more sources

The formation of endoderm-derived taste sensory organs requires a Pax9-dependent expansion of embryonic taste bud progenitor cells.

PLoS Genetics, 2014
In mammals, taste buds develop in different regions of the oral cavity. Small epithelial protrusions form fungiform papillae on the ectoderm-derived dorsum of the tongue and contain one or few taste buds, while taste buds in the soft palate develop ...
Ralf Kist, Michelle Watson, Moira Crosier, Max Robinson, Jennifer Fuchs, Julia Reichelt, Heiko Peters   +6 more
doaj   +1 more source

Molecular and Genetic Basis of Non-Syndromic Tooth Agenesis

Česká Stomatologie a Praktické Zubní Lékařství, 2015
Background: Tooth agenesis represents the most common anomaly of dental development, which according to Online Mendelian Inheritance in Man (OMIM) database, affects approximately 20% of the population.
L. Kramerová, P. Krejčí, E. Míšová, A. Ševecová   +3 more
doaj   +1 more source

Characterization of Zebrafish Pax1b and Pax9 in Fin Bud Development [PDF]

BioMed Research International, 2014
Both Pax1 and Pax9 belong to the important paired box gene family (PAX), which mainly participates in animal development and sclerotome differentiation. To date, the precise molecular mechanism and related signaling pathway of Pax1 remain unclear. In our study, microinjection of morpholino- (MO-) modified antisense oligonucleotides againstpax1binduced ...
Chen, Xuemei, Huang, Huizhe, Wang, Hua, Guo, Fengjin, Du, Xiaogang, Ma, Linqiang, Zhao, Liang, Pan, Zhuma, Gui, Haibo, Yuan, Taixian, Liu, Xin, Song, Lin, Wang, Yiquan, He, Junling, Lei, Han, Gao, Rui   +15 more
openaire   +2 more sources

A review on non-syndromic tooth agenesis associated with PAX9 mutations

Japanese Dental Science Review, 2018
Summary: Tooth agenesis in the reduction of tooth number which includes hypodontia, oligodontia and anodontia is caused by disturbances and gene mutations that occur during odontogenesis.
Nurul Hasyiqin Fauzi, Yunita Dewi Ardini, Zarina Zainuddin, Widya Lestari   +3 more
doaj   +1 more source

A missense mutation in PAX9 in a family with distinct phenotype of oligodontia [PDF]

European Journal of Human Genetics, 2003
Mutations in PAX9 have been described for families in which inherited oligodontia characteristically involves permanent molars. Our study analysed one large family with dominantly inherited oligodontia clinically and genetically. In addition to permanent molars, some teeth were congenitally missing in the premolar, canine, and incisor regions ...
Laura, Lammi, Katri, Halonen, Sinikka, Pirinen, Irma, Thesleff, Sirpa, Arte, Pekka, Nieminen   +5 more
openaire   +2 more sources

Molecular Evolution of the Primate Developmental Genes MSX1 and PAX9 [PDF]

Molecular Biology and Evolution, 2005
In primates, the craniofacial skeleton and the dentition are marked by high levels of interspecific variation. Despite this, there are few comparative species studies conducted at the molecular level to investigate this functional diversity. We have determined nucleotide sequences of MSX1 and PAX9, two developmental genes, in a sample of 27 diverse ...
George H, Perry, Brian C, Verrelli, Anne C, Stone   +2 more
openaire   +2 more sources

Expression of Pax9 in zebrafish ESQE and phenotypes of Pax9 knockdown zebrafish at 7dpf.

, 2015
(A) Normal zebrafish (Lateral view). (B) Pax9 knockdown fish with malformation of the lower jaw (Lateral view). (C) Alcian blue staining shows the orofacial cartilage of normal zebrafish (lateral view).
Xiaoxin Chen (88807), Hao Chen (5190), Andrea Beasley (832732), Yuhui Hu (7203)   +3 more
core   +1 more source