Results 31 to 40 of about 3,069 (190)
Novel PAX9 and COL1A2 missense mutations causing tooth agenesis and OI/DGI without skeletal abnormalities. [PDF]
PLoS ONE, 2012 Inherited dentin defects are classified into three types of dentinogenesis imperfecta (DGI) and two types of dentin dysplasia (DD). The genetic etiology of DD-I is unknown.
Shih-Kai Wang +4 more
doaj +1 more source
Genetic variation among major human geographic groups supports a peculiar evolutionary trend in PAX9. [PDF]
PLoS ONE, 2011 A total of 172 persons from nine South Amerindian, three African and one Eskimo populations were studied in relation to the Paired box gene 9 (PAX9) exon 3 (138 base pairs) as well as its 5'and 3'flanking intronic segments (232 bp and 220 bp ...
Vanessa R Paixão-Côrtes +9 more
doaj +1 more source
PAX7, PAX9 and RYK Expression in Cleft Affected Tissue
Medicina, 2021 Background and Objectives: Cleft lip with or without cleft palate is one of the most common types of congenital malformations. Transcription factors paired box 7 and 9 (PAX7, PAX9) and receptor-like tyrosine kinase (RYK) have been previously associated ...
Mārtiņš Vaivads +2 more
doaj +1 more source
PLoS Genetics, 2014 In mammals, taste buds develop in different regions of the oral cavity. Small epithelial protrusions form fungiform papillae on the ectoderm-derived dorsum of the tongue and contain one or few taste buds, while taste buds in the soft palate develop ...
Ralf Kist +6 more
doaj +1 more source
Journal of Applied Oral Science, 2013 Our research aimed to look into the clinical traits and genetic mutations in sporadic non-syndromic anodontia and to gain insight into the role of mutations of PAX9, MSX1, AXIN2 and EDA in anodontia phenotypes, especially for the PAX9.
Jing WANG +12 more
doaj +1 more source
Molecular and Genetic Basis of Non-Syndromic Tooth Agenesis
Česká Stomatologie a Praktické Zubní Lékařství, 2015 Background: Tooth agenesis represents the most common anomaly of dental development, which according to Online Mendelian Inheritance in Man (OMIM) database, affects approximately 20% of the population.
L. Kramerová +3 more
doaj +1 more source
Characterization of Zebrafish Pax1b and Pax9 in Fin Bud Development [PDF]
BioMed Research International, 2014 Both Pax1 and Pax9 belong to the important paired box gene family (PAX), which mainly participates in animal development and sclerotome differentiation. To date, the precise molecular mechanism and related signaling pathway of Pax1 remain unclear. In our study, microinjection of morpholino- (MO-) modified antisense oligonucleotides againstpax1binduced ...
Chen, Xuemei +15 more
openaire +2 more sources
Msx1 modulates the Pax9-null cardiovascular phenotype [PDF]
, 2017 PhD ThesisDevelopment of the aortic arch arteries from the pharyngeal arch arteries is a complex process requiring the interaction of several tissue types and tightly regulated gene expression during embryogenesis. In this work, the role of transcription
Khasawneh, Ramada Rateb Abdel Karim
core +1 more source
A review on non-syndromic tooth agenesis associated with PAX9 mutations
Japanese Dental Science Review, 2018 Summary: Tooth agenesis in the reduction of tooth number which includes hypodontia, oligodontia and anodontia is caused by disturbances and gene mutations that occur during odontogenesis.
Nurul Hasyiqin Fauzi +3 more
doaj +1 more source
PAX9 Determines Epigenetic State Transition and Cell Fate in Cancer [PDF]
Cancer Research, 2021 Abstract Abnormalities in genetic and epigenetic modifications can lead to drastic changes in gene expression profiles that are associated with various cancer types. Small cell lung cancer (SCLC) is an aggressive and deadly form of lung cancer with limited effective therapies currently ...
Zibo Zhao +8 more
openaire +2 more sources