Results 11 to 20 of about 2,757 (201)
Transcriptional analysis of the human PAX9 promoter [PDF]
Journal of Applied Oral Science, 2010 OBJECTIVES: PAX9 belongs to the Pax family of transcriptional factor genes. This gene is expressed in embryonic tissues such as somites, pharyngeal pouch endoderm, distal limb buds and neural crest-derived mesenchyme.
Carolina Vieira de Almeida +4 more
doaj +6 more sources
Tooth agenesis patterns and variants in PAX9: A systematic review
Japanese Dental Science Review, 2023 Mutations in PAX9 are the most common genetic cause of tooth agenesis (TA). The aim of this study was to systematically review the profiles of the TA and PAX9 variants and establish their genotype-phenotype correlation.
Narin Intarak +4 more
doaj +4 more sources
Msx1 haploinsufficiency modifies the Pax9-deficient cardiovascular phenotype [PDF]
BMC Developmental Biology, 2021 Abstract Background Successful embryogenesis relies on the coordinated interaction between genes and tissues. The transcription factors Pax9 and Msx1 genetically interact during mouse craniofacial morphogenesis, and mice deficient for either gene display abnormal tooth and palate development.
Khasawneh, Ramada +10 more
core +6 more sources
PAX9 (paired box gene 9) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on PAX9 (paired box gene 9), with data on DNA, on the protein encoded, and where the gene is implicated.
E Robson, J Whall, M Eccles
openaire +2 more sources
The phenotype and genotype of PAX9 mutations causing tooth agenesis
Clinical Oral Investigations, 2023 The purpose of this study was to identify associations between PAX9 mutations and clinical features of non-syndromic tooth agenesis patients.Non-syndromic tooth agenesis patients were found to have mutations by whole exome sequencing (WES). Additionally, conservation analysis and three-dimensional structure prediction were also applied to identify ...
Cailing, Jiang +5 more
openaire +3 more sources
Biology Open, 2017 Pax1 and Pax9 play redundant, synergistic functions in the patterning and differentiation of the sclerotomal cells that give rise to the vertebral bodies and intervertebral discs (IVD) of the axial skeleton. They are conserved in mice and humans, whereby
V. Sivakamasundari +6 more
doaj +2 more sources
PAX7, PAX9 and RYK Expression in Cleft Affected Tissue [PDF]
Medicina, 2021 Background and Objectives: Cleft lip with or without cleft palate is one of the most common types of congenital malformations. Transcription factors paired box 7 and 9 (PAX7, PAX9) and receptor-like tyrosine kinase (RYK) have been previously associated ...
Mārtiņš Vaivads +2 more
doaj +2 more sources
The Application of Clinical Genetics, 2018 Ahmed Abu-Siniyeh,1 Omar F Khabour,1 Arwa I Owais2 1Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, Jordan University of Science and Technology, Irbid, Jordan; 2Department of Applied Dental Sciences, Faculty of Applied ...
Abu-Siniyeh A, Khabour OF, Owais AI
doaj +1 more source
PAX9 mutations and genetic synergism in familial tooth agenesis
Annals of the New York Academy of Sciences, 2023 Abstract Familial tooth agenesis (FTA) is one of the most common craniofacial anomalies in humans. Loss‐of‐function mutations in PAX9 and WNT10A have been known to cause FTA with various expressivity.
Kuan‐Yu Chu +9 more
openaire +3 more sources
Pax1 and Pax9 synergistically regulate vertebral column development
Development, 1999 Abstract The paralogous genes Pax1 and Pax9 constitute one group within the vertebrate Pax gene family. They encode closely related transcription factors and are expressed in similar patterns during mouse embryogenesis, suggesting that Pax1 and Pax9 act in similar developmental pathways.
Peters H +5 more
openaire +4 more sources