Results 61 to 70 of about 2,757 (201)
A Zebrafish Model for Studies on Esophageal Epithelial Biology. [PDF]
PLoS ONE, 2015 Mammalian esophagus exhibits a remarkable change in epithelial structure during the transition from embryo to adult. However, the molecular mechanisms of esophageal epithelial development are not well understood.
Hao Chen +3 more
doaj +1 more source
Novel PAX9 Mutations Causing Isolated Oligodontia
Journal of Personalized MedicineHypodontia, i.e., missing one or more teeth, is a relatively common human disease; however, oligodontia, i.e., missing six or more teeth, excluding the third molars, is a rare congenital disorder. Many genes have been shown to cause oligodontia in non-syndromic or syndromic conditions.
Ye Ji Lee +4 more
openaire +2 more sources
MSX1 and PAX9 genetic alteration in Malaysian families with hypodontia [PDF]
, 2017 Hypodontia is characterized by the absence of one to six teeth. Malaysia has a high prevalence of hypodontia (2.8%). This study aimed to investigate the MSX1 mutation with clinical variability in Malaysian hypodontia families and to correlate the ...
Lestari, Widya +4 more
core
Expression Characteristics of PAX7 and Its Prognostic Correlation in Breast Cancer
The Breast Journal, Volume 2026, Issue 1, 2026.Objective To conduct a thorough analysis of public databases to investigate the expression patterns of the PAX7 gene in breast cancer. Methods We gathered gene expression data, clinical details, immunohistochemistry images, and genomic information from breast cancer patients through various public databases, such as TCGA, THPA, GEPIA, and cBioPortal ...
Bahatiguli Silafu +3 more
wiley +1 more source
, 2017 Introduction: PAX9 (Paired box 9) gene is one of the genes which play significant role during craniofacial development. Single nucleotide polymorphism (SNP) in PAX9 has been associated with Class II/Division 2 malocclusion (with or without hypodontia ...
Mokhtar@Makhtar, Khairani Idah +2 more
core +3 more sources
Agenesis of all third molars in two half siblings
Dentistry 3000, 2015 Tooth agenesis is one of the most common dental anomalies and is influenced by factors including patient genetics. Although there are several specific genes associated with certain patterns of agenesis, there does not seem to be a genetic pattern ...
Jamie A Kaufer
doaj +1 more source
Lysine Acetyltransferase 6 in Health and Disease
MedComm, Volume 6, Issue 12, December 2025.KAT6A and its paralog KAT6B have emerged as druggable targets for the treatment of malignancies, especially for breast cancer. Recent progress in drug discovery has promoted the development of dual inhibitors targeting KAT6A and KTA6B, which shows potent antitumor efficacy and manageable toxicity.
Yujing Tan, Jiani Wang, Fei Ma
wiley +1 more source
F1000Research, 2019 Background: Paired-box gene 9 (PAX9) mutation is potentially associated with impaction in some patient populations. Here, we analyzed the relationship between PAX9 polymorphism and the occurrence of maxillary canine impaction.
Evy Eida Vitria +3 more
doaj +1 more source
Small Science, Volume 5, Issue 12, December 2025.The system employs a high density human dental stem cells‐laden oxidized alginate‐based microgel with a "degrade‐to‐active" paradigm that mimics cellular condensation to enhance cell viability, achieve robust vascularization, and promote subsequent dental organogenesis, which is enabled by rapid degradation along with the elimination of residual ...
Chao Liang +22 more
wiley +1 more source
Journal of Orofacial Sciences, 2016 Background and Aim: Recent studies demonstrate direct roles of different genes during formation of secondary palate, but there are no still data about local expression and distribution of gene products in cleft palate affected human tissue. Thus, the aim
Benita Krivicka-Uzkurele, Mara Pilmane
doaj +1 more source