Results 71 to 80 of about 7,348,517 (171)

Agenesis of all third molars in two half siblings

Dentistry 3000, 2015
Tooth agenesis is one of the most common dental anomalies and is influenced by factors including patient genetics. Although there are several specific genes associated with certain patterns of agenesis, there does not seem to be a genetic pattern ...
Jamie A Kaufer
doaj   +1 more source

Whole genome sequencing reveals novel non-synonymous mutation in ectodysplasin A (EDA) associated with non-syndromic X-linked dominant congenital tooth agenesis. [PDF]

PLoS ONE, 2014
Congenital tooth agenesis in human is characterized by failure of tooth development during tooth organogenesis. 300 genes in mouse and 30 genes in human so far have been known to regulate tooth development. However, candidature of only 5 genes viz. PAX9,
Tanmoy Sarkar, Rajesh Bansal, Parimal Das   +2 more
doaj   +1 more source

Application of GLAD-PCR Assay for Study on DNA Methylation in Regulatory Regions of Some Tumor-Suppressor Genes in Lung Cancer

Chinese Journal of Lung Cancer, 2019
Hypermethylation of the gene regulatory regions are common for many cancer diseases. In this work we applied GLAD-PCR assay for identificating of the aberrantly methylated RCGY sites in the regulatory regions of some downregulated genes in tissue samples
N.A. Smetannikova, A.A. Evdokimov, N.A. Netesova, M.A. Abdurashitov, A.G. Akishev, E.V. Dubinin, P.I. Pozdnyakov, I.V. Vihlyanov, M.K. Nikitin, E.B. Topolnitsky, A.B. Karpov, S.A. Kolomiets, S.Kh. Degtyarev   +12 more
doaj   +1 more source

Lysine Acetyltransferase 6 in Health and Disease

MedComm, Volume 6, Issue 12, December 2025.
KAT6A and its paralog KAT6B have emerged as druggable targets for the treatment of malignancies, especially for breast cancer. Recent progress in drug discovery has promoted the development of dual inhibitors targeting KAT6A and KTA6B, which shows potent antitumor efficacy and manageable toxicity.
Yujing Tan, Jiani Wang, Fei Ma
wiley   +1 more source

The presence and distribution of various genes in postnatal CLP-affected palatine tissue

Maxillofacial Plastic and Reconstructive Surgery
Background Worldwide cleft lip with or without a cleft palate (CL/P) is the most common craniofacial birth defect. Apart from changes in facial appearance, additionally affected individuals often suffer from various associated comorbidities requiring ...
Jana Goida, Mara Pilmane
doaj   +1 more source

Polarized Sonic Hedgehog Protein Localization and a Shift in the Expression of Region-Specific Molecules Is Associated With the Secondary Palate Development in the Veiled Chameleon

Frontiers in Cell and Developmental Biology, 2020
Secondary palate development is characterized by the formation of two palatal shelves on the maxillary prominences, which fuse in the midline in mammalian embryos.
Marek Hampl, Marek Hampl, Jana Dumkova, Michaela Kavkova, Hana Dosedelova, Anna Bryjova, Oldrich Zahradnicek, Oldrich Zahradnicek, Martin Pyszko, Milos Macholan, Tomas Zikmund, Jozef Kaiser, Marcela Buchtova, Marcela Buchtova   +13 more
doaj   +1 more source

Harnessing Oxidized Alginate Microgels for Rapid and Self‐Assembling Dental Tissue Organogenesis In Vitro and In Vivo

Small Science, Volume 5, Issue 12, December 2025.
The system employs a high density human dental stem cells‐laden oxidized alginate‐based microgel with a "degrade‐to‐active" paradigm that mimics cellular condensation to enhance cell viability, achieve robust vascularization, and promote subsequent dental organogenesis, which is enabled by rapid degradation along with the elimination of residual ...
Chao Liang, Shuxuan Wu, Ziqi Huang, Zhenzhen Wu, Siyuan Chen, Feiming Li, Karrie Mei‐Yee Kiang, Gilberto Ka‐Kit Leung, Indong Jun, Hwan D. Kim, Ann‐Na Cho, Hee Jung Lee, Honghyun Park, Yiu Yan Leung, Seong Jun Kim, Seil Sohn, Haram Nah, Jae Seo Lee, Il Keun Kwon, Dong‐Nyoung Heo, Sang‐woo Lee, Zhaoming Wu, Sang Jin Lee   +22 more
wiley   +1 more source

Comparative Transcriptomics Reveals a Dual Role of the Epidermal Differentiation Complex in the Skin and the Oesophagus

Experimental Dermatology, Volume 34, Issue 12, December 2025.
ABSTRACT The epidermal differentiation complex (EDC) is a cluster of genes implicated in the control of the skin barrier. However, some EDC genes are also expressed at high levels in the human oesophagus. To determine whether the expression of EDC genes in the oesophagus is evolutionarily conserved, we performed comparative transcriptomic analyses of ...
Attila Placido Sachslehner, Julia Lachner, Veronika Mlitz, Bahar Golabi, Claudia Hess, Wolfgang Sipos, Leopold Eckhart   +6 more
wiley   +1 more source

Morphological variation of the maxillary lateral incisor

Japanese Dental Science Review, 2014
The maxillary lateral incisor is a variable tooth morphologically. This tooth frequently shows reduction in size, and also various alterations in shape, for example, peg-shaped, cone-shaped, barrel-shaped and canine-shaped.
Shintaro Kondo, Grant Townsend, Masanobu Matsuno   +2 more
doaj   +1 more source

ABCC11 Earwax Trait and Genotype Are Suitable Tools for Introductory Labs to Learn Genetics and Molecular Techniques

Biochemistry and Molecular Biology Education, Volume 53, Issue 6, Page 603-609, November/December 2025.
ABSTRACT Professional experiments in genetic research usually start in a class at university. However, interest in genetic research techniques from an early age is essential. We have continuously performed a short genetic experimental course for high school students using a simple molecular experiment and computer‐based learning for Mendelian ...
Tohru Ohta, Rie Takai, Akiko Yoshida, Durga Paudel, Sarita Giri, Takao Kitagawa, Toshiya Arakawa, Yasuhiro Kuramitsu, Tomoharu Tokutomi   +8 more
wiley   +1 more source