Results 81 to 90 of about 7,348,517 (171)

Effects of PAX9 and MSX1 gene variants to hypodontia, tooth size and the type of congenitally missing teeth

Cellular and Molecular Biology, 2016
ooth agenesis, affecting up to 20% of human population, is one of the most common congenital disorder. The most frequent form of tooth agenesis is known as hypodontia, which is characterized by the absence of one to five permanent teeth excluding third molars.
D, Kirac, F, Eraydin, T, Avcilar, K, Ulucan, F, Özdemir, A I, Guney, E Ç, Kaspar, E, Keshi, T, Isbir   +8 more
openaire   +4 more sources

A periodic pattern generator for dental diversity

BMC Biology, 2008
Background Periodic patterning of iterative structures is a fundamental process during embryonic organization and development. Studies have shown how gene networks are employed to pattern butterfly eyespots, fly bristles and vertebrate epithelial ...
Streelman J Todd, Bloomquist Ryan F, Fraser Gareth J   +2 more
doaj   +1 more source

Characterization of pax1, pax9, and uncx sclerotomal genes during Xenopus laevis embryogenesis

Developmental Dynamics, 2013
Background: The axial skeleton develops from the sclerotome, a mesenchymal cell population derived from somites. Sclerotomal cells migrate from somites to the perinotochordal and perineural space where they differentiate into chondrocytes to form cartilage and bone.
Sanchez, Romel Sebastian, Sanchez, Sara Serafina del V.   +1 more
openaire   +3 more sources

Genetic factors define CPO and CLO subtypes of nonsyndromicorofacial cleft.

PLoS Genetics, 2019
Nonsyndromic orofacial cleft (NSOFC) is a severe birth defect that occurs early in embryonic development and includes the subtypes cleft palate only (CPO), cleft lip only (CLO) and cleft lip with cleft palate (CLP).
Lulin Huang, Zhonglin Jia, Yi Shi, Qin Du, Jiayu Shi, Ziyan Wang, Yandong Mou, Qingwei Wang, Bihe Zhang, Qing Wang, Shi Ma, He Lin, Shijun Duan, Bin Yin, Yansong Lin, Yiru Wang, Dan Jiang, Fang Hao, Lin Zhang, Haixin Wang, Suyuan Jiang, Huijuan Xu, Chengwei Yang, Chenghao Li, Jingtao Li, Bing Shi, Zhenglin Yang   +26 more
doaj   +1 more source

Genetic Variants of MSX1, PAX9, and AXIN2 in Mayan Probands with Dental Agenesis from Yucatan, Mexico

Odovtos - International Journal of Dental Sciences
The present study aimed to determine the genetic variants of PAX9, MSX1, and AXIN2 in Mayan probands with non-syndromic dental agenesis (NSDA) from Yucatan, Mexico. We sequenced DNA of specific exons of the PAX9, MSX1, and AXIN2 genes by using the Sanger
Nayelli A. González-Pérez, J. R. Herrera-Atoche, P. López-González, Ramón Pacheco-Arjona, Jorge A. Rangel-Méndez, Joel E. Canul-May, J. Sosa-Escalante, I. D. Zúñiga-Herrera, F. Aguilar-Ayala, L. González-Herrera   +9 more
semanticscholar   +1 more source

Characterization of novel MSX1 mutations identified in Japanese patients with nonsyndromic tooth agenesis.

PLoS ONE, 2014
Since MSX1 and PAX9 are linked to the pathogenesis of nonsyndromic tooth agenesis, we performed detailed mutational analysis of these two genes sampled from Japanese patients.
Seishi Yamaguchi, Junichiro Machida, Munefumi Kamamoto, Masashi Kimura, Akio Shibata, Tadashi Tatematsu, Hitoshi Miyachi, Yujiro Higashi, Peter Jezewski, Atsuo Nakayama, Kazuo Shimozato, Yoshihito Tokita   +11 more
doaj   +1 more source

Diagnostic and prognostic biomarkers associated with histotype in advanced epithelial ovarian cancer

Scientific Reports
Despite advances in cancer treatments, epithelial ovarian cancer (EOC) remains the leading cause of death among gynecologic cancers. EOC is stratified into five main histopathological subtypes: high-grade serous carcinoma (HGSC), low-grade serous ...
Ella Ittner, Hugo Swenson, Lucas Werner, Elisabeth Werner Rönnerman, Constantina Mateoiu, Anikó Kovács, Pernilla Dahm-Kähler, Ghassan Saed, Per Karlsson, Toshima Z. Parris, Khalil Helou   +10 more
doaj   +1 more source

A Signaling-Threshold Framework for Human Tooth Agenesis: Integrating Molecular Genetics with Developmental Field Theory. [PDF]

Int J Mol Sci
Kuc AE, Kuc P, Kuc N, Sulewska M, Tylicka M, Sarul M.   +5 more
europepmc   +1 more source

MSX1 and PAX9 Polymorphisms and Their Association With Lateral Incisor Morphology in Patients With Maxillary Canine Impaction. [PDF]

Med Sci Monit
Todorović A, Filipović G, Stefanović N, Vujić S, Todorović K, Mitić V, Janošević P, Radojičić J, Šćepan I.   +8 more
europepmc   +1 more source

Unlocking predictive genetic factors with artificial intelligence: relationship between dental impaction and hypodontia evaluated via association-rule algorithms: a case-control study. [PDF]

Saudi Dent J
Alhazmi N, Alaqla A, Almuzzaini B, Aldrees M, Alnaqa G, Almasoud F, Thomas SK, Alshamlan H.   +7 more
europepmc   +1 more source