Results 11 to 20 of about 1,648 (133)

Transcriptional analysis of the human PAX9 promoter [PDF]

Journal of Applied Oral Science, 2010
OBJECTIVES: PAX9 belongs to the Pax family of transcriptional factor genes. This gene is expressed in embryonic tissues such as somites, pharyngeal pouch endoderm, distal limb buds and neural crest-derived mesenchyme.
Carolina Vieira de Almeida, Simone Caixeta de Andrade, Cristiane Pereira Borges Saito, Liza Lima Ramenzoni, Sergio Roberto Peres Line   +4 more
doaj   +2 more sources

Functional Screenings Identify Regulatory Variants Associated with Breast Cancer Susceptibility

Current Issues in Molecular Biology, 2021
Genome-wide association studies (GWAS) have identified more than 2000 single nucleotide polymorphisms (SNPs) associated with breast cancer susceptibility, most of which are located in the non-coding region.
Naixia Ren, Yingying Li, Yulong Xiong, Panfeng Li, Yutian Ren, Qilai Huang   +5 more
doaj   +2 more sources

Association between polymorphism in the promoter region (G/C-915) of PAX9 gene and third molar agenesis

Journal of Applied Oral Science, 2007
PURPOSE: Hypodontia is the congenital absence of one or more (up to six) permanent and/or deciduous teeth, being one of the most common alterations of the human dentition.
Fabio José Bianch, Tiago Franco de Oliveira, Cristiane Borges Pereira Saito, Regina Célia Rocha Peres, Sérgio Roberto Peres Line   +4 more
doaj   +1 more source

PAX9 polymorphism and susceptibility to sporadic non-syndromic severe anodontia: a case-control study in southwest China

Journal of Applied Oral Science, 2013
Our research aimed to look into the clinical traits and genetic mutations in sporadic non-syndromic anodontia and to gain insight into the role of mutations of PAX9, MSX1, AXIN2 and EDA in anodontia phenotypes, especially for the PAX9.
Jing WANG, Yuanzhi XU, Jing CHEN, Feiyu WANG, Renhuan HUANG, Songtao WU, Linjing SHU, Jingyi QIU, Zhi YANG, Junjie XUE, Raorao WANG, Jilin ZHAO, Wenli LAI   +12 more
doaj   +1 more source

The role of Msx1 and Pax9 in pathogenetic mechanisms of tooth agenesis

Dental Journal, 2009
Background: Tooth agenesis is one of the most common developmental anomalies in human, which one or a few teeth are absent because they have never formed, may cause cosmetic or occlusal harm, while severe agenesis which are relatively rare require ...
Yani Corvianindya Rahayu, dyah Setyorini
doaj   +1 more source

A transcription factor-based mechanism for mouse heterochromatin formation

, 2012
Heterochromatin is important for genome integrity and stabilization of gene-expression programs. We have identified the transcription factors Pax3 and Pax9 as redundant regulators of mouse heterochromatin, as they repress RNA output from major satellite ...
Pagani M., Opravil S., Scaranaro M., Popow J., Brabletz T., Shukeir N., Meidhof S., Gerle B., Lachner M., Bulut-Karslioglu A., Perrera V., Manke T., Jenuwein T., De La Rosa-Velazquez I. A., Van De Nobelen S.   +14 more
core   +2 more sources

FOXN1: a master regulator gene of thymic epithelial development programme

Frontiers in Immunology, 2013
T cell ontogeny is a sophisticated process, which takes place within the thymus through a series of well-defined discrete stages. The process requires a proper lympho-stromal interaction.
Rosa eRomano, Loredana ePalamaro, Anna eFusco, Giuliana eGiardino, Vera eGallo, Luigi eDel Vecchio, Claudio ePignata   +6 more
doaj   +1 more source

Function of Gata-2 in thymic epithelial cells : a transcription factor identified from gene expression analysis of endodermal cells committed to thymic epithelial cell fate [PDF]

, 2010
The thymus structure composes of clear morphological regions. The T-cell precursors enter the thymus in the cortico-medullary junction and migrate through the cortex towards the sub capsular region and back through to the cortex into the medulla.
Na, Kyung-Jae
core   +1 more source

Genetic factors define CPO and CLO subtypes of nonsyndromicorofacial cleft.

PLoS Genetics, 2019
Nonsyndromic orofacial cleft (NSOFC) is a severe birth defect that occurs early in embryonic development and includes the subtypes cleft palate only (CPO), cleft lip only (CLO) and cleft lip with cleft palate (CLP).
Lulin Huang, Zhonglin Jia, Yi Shi, Qin Du, Jiayu Shi, Ziyan Wang, Yandong Mou, Qingwei Wang, Bihe Zhang, Qing Wang, Shi Ma, He Lin, Shijun Duan, Bin Yin, Yansong Lin, Yiru Wang, Dan Jiang, Fang Hao, Lin Zhang, Haixin Wang, Suyuan Jiang, Huijuan Xu, Chengwei Yang, Chenghao Li, Jingtao Li, Bing Shi, Zhenglin Yang   +26 more
doaj   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source