Results 31 to 40 of about 1,625 (96)

Harnessing Oxidized Alginate Microgels for Rapid and Self‐Assembling Dental Tissue Organogenesis In Vitro and In Vivo

Small Science, Volume 5, Issue 12, December 2025.
The system employs a high density human dental stem cells‐laden oxidized alginate‐based microgel with a "degrade‐to‐active" paradigm that mimics cellular condensation to enhance cell viability, achieve robust vascularization, and promote subsequent dental organogenesis, which is enabled by rapid degradation along with the elimination of residual ...
Chao Liang, Shuxuan Wu, Ziqi Huang, Zhenzhen Wu, Siyuan Chen, Feiming Li, Karrie Mei‐Yee Kiang, Gilberto Ka‐Kit Leung, Indong Jun, Hwan D. Kim, Ann‐Na Cho, Hee Jung Lee, Honghyun Park, Yiu Yan Leung, Seong Jun Kim, Seil Sohn, Haram Nah, Jae Seo Lee, Il Keun Kwon, Dong‐Nyoung Heo, Sang‐woo Lee, Zhaoming Wu, Sang Jin Lee   +22 more
wiley   +1 more source

Comparative Transcriptomics Reveals a Dual Role of the Epidermal Differentiation Complex in the Skin and the Oesophagus

Experimental Dermatology, Volume 34, Issue 12, December 2025.
ABSTRACT The epidermal differentiation complex (EDC) is a cluster of genes implicated in the control of the skin barrier. However, some EDC genes are also expressed at high levels in the human oesophagus. To determine whether the expression of EDC genes in the oesophagus is evolutionarily conserved, we performed comparative transcriptomic analyses of ...
Attila Placido Sachslehner, Julia Lachner, Veronika Mlitz, Bahar Golabi, Claudia Hess, Wolfgang Sipos, Leopold Eckhart   +6 more
wiley   +1 more source

E‐Cigarette and Vanillin Exposure Disrupts Cardiovascular Development in Xenopus laevis

Birth Defects Research, Volume 117, Issue 10, October 2025.
ABSTRACT Introduction Congenital heart defects (CHDs) are a leading cause of perinatal mortality, and maternal cigarette smoking is a well‐established risk factor. In recent years, electronic cigarette (e‐cigarette) use has surged, yet its safety during pregnancy remains poorly defined.
James E. Black III, Thomas O. Raymond, Amanda J. G. Dickinson   +2 more
wiley   +1 more source

Deconstructing the Thymic Microenvironment Through Genesis to Senescence

Immunological Reviews, Volume 332, Issue 1, July 2025.
ABSTRACT The thymus is essential for adaptive immunity, orchestrating the differentiation of hematopoietic progenitors into various T‐cell lineages. Thymic epithelial cells (TECs) impart this unique function by mediating the major checkpoints in T‐cell differentiation while also imposing stringent tolerance processes required to prevent autoimmunity ...
Michael D'Andrea, Kelin Zhao, Daniel H. D. Gray   +2 more
wiley   +1 more source

Genetic architecture of craniofacial morphogenesis: roles of <i>PAX3</i>, <i>PAX7</i>, and <i>PAX9</i>. [PDF]

Front Cell Dev Biol
Wang K, Li N, Liu W, Li YG, Ren F.
europepmc   +1 more source

<i>Alx1</i> is required for enamel knot formation during incisor morphogenesis. [PDF]

Front Physiol
Zheng X, Lu H, Chen M, Xu Y, Lin C, Lv Y, Zhang Y, Hu X, Lin M.   +8 more
europepmc   +1 more source

A Signaling-Threshold Framework for Human Tooth Agenesis: Integrating Molecular Genetics with Developmental Field Theory. [PDF]

Int J Mol Sci
Kuc AE, Kuc P, Kuc N, Sulewska M, Tylicka M, Sarul M.   +5 more
europepmc   +1 more source

Paired-Box (PAX) Gene Signatures as a Biomarker of Breast Cancer Progression. [PDF]

Int J Mol Sci
Scimeca M, Scioli MP, Palumbo V, Funke L, Woodsmith J, Servadei F, Giacobbi E, Seghetti C, Buonomo OC, Candi E, Treglia M, Marsella LT, Melino G, Mauriello A, Bonfiglio R.   +14 more
europepmc   +1 more source

MSX1 and PAX9 Polymorphisms and Their Association With Lateral Incisor Morphology in Patients With Maxillary Canine Impaction. [PDF]

Med Sci Monit
Todorović A, Filipović G, Stefanović N, Vujić S, Todorović K, Mitić V, Janošević P, Radojičić J, Šćepan I.   +8 more
europepmc   +1 more source

Epigenetic, Genetic, and Functional Germline Alterations of <i>PAX</i> Genes in Human Pathology: A Comprehensive Update. [PDF]

Curr Issues Mol Biol
Gomez VL, Wegner S, Ocejo S, Perez D, Jabbour D, Fernandez V, Abulaban A, Bahmad M, Elajami TK, Abou-Kheir W, Bahmad HF.   +10 more
europepmc   +1 more source