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Staphylococcus aureus DivIB is a peptidoglycan-binding protein that is required for a morphological checkpoint in cell division [PDF]
, 2014 Bacterial cell division is a fundamental process that requires the coordinated actions of a number of proteins which form a complex macromolecular machine known as the divisome.
Bottomley, Amy L. +5 more
core +1 more source
Health Science Reports, Volume 8, Issue 11, November 2025.ABSTRACT Background and Aims The COVID‐19 pandemic has profoundly impacted global public health, particularly the epidemiology and antimicrobial resistance patterns of pathogens. This study aimed to assess the influence of COVID‐19 on the isolation rates of Haemophilus influenzae in Shandong Province, providing data support for empirical precision ...
Yanmeng Sun +4 more
wiley +1 more source
Resistance of Clostridium difficile from ribotype 017 to imipenem: contribution of the whole genome sequencing [PDF]
, 2018 A infeção por Clostridium difficile é a principal causa de diarreia infeciosa associada aos cuidados de saúde. Neste estudo, caracterizámos um conjunto de estirpes clínicas de Clostridium difficile, provenientes de diversos hospitais portugueses, com ...
Borges, Vítor +10 more
core
MicrobiologyOpen, Volume 14, Issue 5, October 2025.Klebsiella pneumoniae isolate KPNW showed resistance to all clinically relevant antibiotics. Upon whole genome sequencing and characterization, we detected a large number of antimicrobial resistance genes, resistance‐associated point mutations, virulence determinants, heavy metal resistance genes, and mobile genetic elements in errorits genome ...
Md. Wahid Murad +3 more
wiley +1 more source
The 2018 Garrod Lecture: Preparing for the Black Swans of Resistance [PDF]
, 2018 The need for governments to encourage antibiotic development is widely agreed, with ‘Market Entry Rewards’ being suggested. Unless these are to be spread widely – which is unlikely given the $1 billion sums proposed– we should be wary, for this approach ...
Livermore, David
core +1 more source
Predicting the Proteins of Angomonas deanei, Strigomonas culicis and Their Respective Endosymbionts Reveals New Aspects of the Trypanosomatidae Family [PDF]
, 2013 Endosymbiont-bearing trypanosomatids have been considered excellent models for the study of cell evolution because the host protozoan co-evolves with an intracellular bacterium in a mutualistic relationship.
Afonso de Menezes, Claudia Beatriz +39 more
core +11 more sources
mBio, 2023 Clostridioides difficile remains a key cause of healthcare-associated infection, with multidrug-resistant (MDR) lineages causing high-mortality (≥20%) outbreaks.
Kate E. Dingle +11 more
doaj +1 more source
Impact of sar and agr on methicillin resistance in Staphylococcus aureus [PDF]
, 2017 The global regulators agr and sar control expression of cell wall and extracellular proteins. Inactivation of either sar and/or agr in a typical heterogeneously methicillin-resistant Staphylococcus aureus resulted in a small but reproducible decrease in ...
Berger-Bächi, B. +2 more
core
Identification of a new family of enzymes with potential -acetylpeptidoglycan esterase activity in both Gram-positive and Gram-negative bacteria [PDF]
, 2005 Background The metabolism of the rigid bacterial cell wall heteropolymer peptidoglycan is a dynamic process requiring continuous biosynthesis and maintenance involving the coordination of both lytic and synthetic enzymes.
Joel T Weadge +2 more
core +2 more sources
Imipenem Resistance in Clostridium difficile Ribotype 017, Portugal
Emerging Infectious Diseases, 2018 We describe imipenem-resistant and imipenem-susceptible clinical isolates of Clostridium difficile ribotype 017 in Portugal. All ribotype 017 isolates carried an extra penicillin-binding protein gene, pbp5, and the imipenem-resistant isolates had ...
Joana Isidro +10 more
doaj +1 more source