Results 91 to 100 of about 2,944 (157)

Additional file 17: of Stationary phase persister formation in Escherichia coli can be suppressed by piperacillin and PBP3 inhibition

, 2019
Table S2. DNA oligonucleotides. (DOCX 17 kb)
Aedo, Sandra, Orman, Mehmet, Brynildsen, Mark   +2 more
openaire   +1 more source

Additional file 16: of Stationary phase persister formation in Escherichia coli can be suppressed by piperacillin and PBP3 inhibition

, 2019
Table S1. Bacterial strains and plasmids. (DOCX 24 kb)
Aedo, Sandra, Orman, Mehmet, Brynildsen, Mark   +2 more
openaire   +1 more source

Prevalence and molecular characteristics of β-lactam resistance in non-typeable Haemophilus influenzae isolates in Korea

Annals of Clinical Microbiology
Background: Haemophilus influenzae is the causative pathogen for various infectious diseases, such as respiratory infections, otitis media, sinusitis, and meningitis.
Eun-Young Kim, Yeon Chan Choi, Hyeon Jin Choi, Si Hyun Kim, Jihyun Cho, Seok Hoon Jeong, Dokyun Kim, Hyun Soo Kim, Soo Hyun Kim, Young Ah Kim, Young Ree Kim, Nam Hee Ryoo, Jong Hee Shin, Kyeong Seob Shin, Young Uh, Jeong Hwan Shin   +15 more
doaj   +1 more source

The role of GpsB in Staphylococcus aureus cell morphogenesis

mBio
For decades, cells of the Gram-positive bacterial pathogen Staphylococcus aureus were thought to lack a dedicated elongation machinery. However, S.
Sara F. Costa, Bruno M. Saraiva, Helena Veiga, Leonor B. Marques, Simon Schäper, Marta Sporniak, Daniel E. Vega, Ana M. Jorge, Andreia M. Duarte, António D. Brito, Andreia C. Tavares, Patricia Reed, Mariana G. Pinho   +12 more
doaj   +1 more source

Tracing the evolutionary trajectory of the IncP-2 plasmid co-harboring blaIMP-45 and blaVIM-1: an outbreak of Pseudomonas aeruginosa co-producing IMP-45 and VIM-1 carbapenemases in China

Frontiers in Cellular and Infection Microbiology
BackgroundCarbapenem-resistant Pseudomonas aeruginosa (CRPA) poses a significant global health risk, particularly for immunocompromised individuals. This study documents an outbreak of CRPA strains co-harboring blaVIM-1 and blaIMP-45 on IncP-2 plasmids ...
Yiqun Ma, Yiqun Ma, Yiqun Ma, Zichen Lei, Zichen Lei, Zichen Lei, Yulin Zhang, Yulin Zhang, Qi Liu, Qi Liu, Qi Liu, Feilong Zhang, Feilong Zhang, Feilong Zhang, Hao Zu, Xinrui Yang, Xinrui Yang, Xinrui Yang, Ziyao Li, Ziyao Li, Ziyao Li, Binghuai Lu, Binghuai Lu, Binghuai Lu, Binghuai Lu, Binghuai Lu   +25 more
doaj   +1 more source

Biophysical and biochemical studies of penicillin binding proteins and novel PBP3 inhibitors [PDF]

Antimicrobial resistance presents a worrying and growing threat to modern medicine. Combatting this challenge requires the discovery of new antimicrobial compounds, which are insensitive to current resistance pathways. One of the most important classes of antibiotics, β-lactams, target penicillin binding proteins (PBPs), a family of enzymes that ...
openaire  

In-vitro and In-silico Study of Bioactive Compounds from Coccocarpia erythroxyli as Inhibitors Targeting PBP3 (6ILE) for Antibacterial Applications

Trends in Sciences
Lichens are recognized as sources of diverse bioactive metabolites with potential antibacterial properties. This study evaluated the antibacterial activity of Coccocarpia erythroxyli (Spreng.) Swinscow & Krog and its interaction with Penicillin-Binding Protein 3 (PBP3, PDB ID: 6I1E). Methanol extracts of C.
Oky Kusuma Atni, Erman Munir, Nursahara Pasaribu   +2 more
openaire   +1 more source

Functional characterisation of the activities and interactions of Gram-negative penicillin-binding proteins PBP1b and PBP3 [PDF]

The clinical introduction of antibiotics revolutionised medicine, however the emergence of resistant bacteria is threatening their use. Of particular worry are multi-drug resistant Gram-negative bacteria that have evaded the development of any new treatment classes since the 1960’s, making them particularly difficult to treat.
openaire  

Acid-dependent beta-lactam resistance in <i>Klebsiella pneumoniae</i> is mediated by paralogous class B PBPs and the class A PBP, PBP1b. [PDF]

mBio
Beagle S, Levin PA.
europepmc   +1 more source

Comparative activity of sulbactam and sulbactam/durlobactam against carbapenem-resistant A. baumannii isolates producing OXA-23 or OXA-23 plus PER-1 enzymes. [PDF]

J Antibiot (Tokyo)
Mirza HC, Üsküdar Güçlü A, Ünlü S, Yalçın S.   +3 more
europepmc   +1 more source