Results 151 to 160 of about 14,363 (238)

Validation of Computational Approaches for Antiretroviral Dose Optimization (vol 60, pg 3838, 2016) [PDF]

, 2016
Dickinson, Laura, Owen, Andrew, Siccardi, Marco   +2 more
core   +1 more source

Development of a Pregnancy-Specific Physiologically Based Pharmacokinetics (PBPK) Model for Aspirin. [PDF]

CPT Pharmacometrics Syst Pharmacol
Collins-Smith A, Kammala AK, Phelps MA, Wang XM, Menon R, Costantine MM.   +5 more
europepmc   +1 more source

High-Throughput Physiologically Based Pharmacokinetic Model for Rodent Pharmacokinetics Prediction Using Machine Learning-Predicted Inputs and a Large <i>In Vivo</i> Pharmacokinetics Data Set. [PDF]

Mol Pharm
Bassani D, Andrews-Morger A, Zhang J, Docci L, Cecere G, Pähler A, Belubbi T, Laye P, Shih I, Parrott NJ.   +9 more
europepmc   +1 more source

Physiologically Based Pharmacokinetic Modeling in Patients With Hepatic Impairment: Are Changes in Bosutinib Exposure Profiles Driven by Altered Absorption or Distribution? [PDF]

CPT Pharmacometrics Syst Pharmacol
Muto C, Jones HM, Yamazaki S.
europepmc   +1 more source

Sorafenib in mice - A Pharmacokinetic study [PDF]

, 2015
Abbiati, ROBERTO ANDREA, Cavallaro, Gennara, Craparo, Emanuela F., Manca, Davide   +3 more
core   +1 more source

Assessment of Vancomycin Penetration into Cerebrospinal Fluid in Patients with Ventriculitis Using a Physiologically Based Pharmacokinetic Approach. [PDF]

Pharm Res
Guimarães LMA, de Vasconcellos Nacif LO, de Lima Benzi JR, de Oliveira Santos MT, Yamada C, Tuon FF, Telles JP, de Lima Moreira F.   +7 more
europepmc   +1 more source

Dose Optimization of Tilmicosin against <i>Pasteurella multocida</i> in Swine by Physiologically Based Pharmacokinetic-Pharmacodynamic Model. [PDF]

J Agric Food Chem
Sun L, Zhang C, Mi K, Wang H, Pan Y, Tao Y, Huang L.   +6 more
europepmc   +1 more source

Addressing Adherence Using Genotype-Specific PBPK Modeling—Impact of Drug Holidays on Tamoxifen and Endoxifen Plasma Levels [PDF]

, 2017
Georg Hempel, Kristin J. R. Dickschen, Michael Block, Stefan Willmann   +3 more
core   +1 more source

Validating Physiologically-Based Pharmacokinetic Models Using the Continuous Ranked Probability Score: Beyond Being Correct on Average. [PDF]

CPT Pharmacometrics Syst Pharmacol
Sluijterman L, van Borselen M, Greupink R, IntHout J.   +3 more
europepmc   +1 more source

Modellierung PBPK-relevanter Verteilungskoeffizienten organischer Stoffe

, 2014
Drei Verteilungskoeffizienten, die für physiologie-basierte Pharmakokinetik (PBPK)-Modelle relevant sind, wurden mit verschiedenen Ansätzen modelliert. Für den Blut/Luft-Verteilungskoeffizienten wurde ein auf linearen Solvatations-Energie-Beziehungen (LSER) beruhendes Literaturmodell angewendet und diskutiert.
openaire   +1 more source