Results 181 to 190 of about 16,022 (277)

Associations of Perfluoroalkyl Substances (PFAS) with Lower Birth Weight: An Evaluation of Potential Confounding by Glomerular Filtration Rate Using a Physiologically Based Pharmacokinetic Model (PBPK)

, 2015
Marc-André Verner, Anne E. Loccisano, Nils‐Halvdan Morken, Miyoung Yoon, Huali Wu, Robin McDougall, Mildred Maisonet, Michele Marcus, Reiko Kishi, Chihiro Miyashita, Mei‐Huei Chen, Wu‐Shiun Hsieh, Melvin E. Andersen, Harvey J. Clewell, Matthew P. Longnecker   +14 more
openalex   +1 more source

Sorafenib in mice - A Pharmacokinetic study [PDF]

, 2015
Abbiati, ROBERTO ANDREA, Cavallaro, Gennara, Craparo, Emanuela F., Manca, Davide   +3 more
core   +1 more source

Comparison of dermal and inhalation routes of entry for organic chemicals [PDF]

The quantitative comparison of the chemical concentration inside the body as the result of a dermal exposure versus an inhalation exposure is useful for assessing human health risks and deciding on an appropriate protective posture.
Clewell, Harvey J., III, Jepson, Gary W., Mcdougal, James N.   +2 more
core   +1 more source

P22-05: Animal-free assessment of developmental toxicity: Combining PBPK modeling with the ReproTracker assay

, 2023
Marjory Moreau, A. Jamalpoor, Sabine Hartvelt, Jeff Fisher, Giel Hendriks, Andy Nong   +5 more
openalex   +1 more source

Role of PBPK modeling in drug discovery: opportunities and limitations [PDF]

, 2007
Agnès Poirier, Christoph Funk, Thierry Lavé   +2 more
openalex   +1 more source

Validation of Computational Approaches for Antiretroviral Dose Optimization (vol 60, pg 3838, 2016) [PDF]

, 2016
Dickinson, Laura, Owen, Andrew, Siccardi, Marco   +2 more
core   +1 more source

A novel PBPK/PD model of preclinical data projects the human pharmacologically active dose of a Biologic that modulates immunosuppressive immune cells in the tumor microenvironment

Sameed Ahmed, Eun-Ah Bae, Dean Bottino, Cierra N. Casson, Carla Guarino, Tiquella Hatten, Sarah Hesse, Natasha Iartchouk, Jessica Riceberg, Brandon Wilkinson, Tomoki Yoneyama, Tingting Zhang   +11 more
openalex   +1 more source

Bayesian population PBPK approach for support of drug development

, 2016
Markus Krauß
openalex   +2 more sources

[[alternative]]Parameters Estimation of Physiologically-Based Pharmacokinetic Model Considering Dynamic Models [PDF]

計畫編號：NSC92-2118-M032-002研究期間：200308~200407研究經費：434,000[[sponsorship ...
陳主智
core  

Development of a Physiologically Based Pharmacokinetic (PBPK) Simulation Model for Nicotine. [PDF]

Biopharm Drug Dispos
Kim B, Bae SH, Bashar M, Yi B, Rahman MA, Awuah P, Hartog M, Panarsky R, Zhang T.   +8 more
europepmc   +1 more source