Results 131 to 140 of about 12,486 (248)

Correction to: A PBPK model to evaluate zebrafish eleutheroembryos' actual exposure: bisphenol A and analogs' (AF, F, and S) case studies. [PDF]

Environ Sci Pollut Res Int, 2023
Billat PA, Brochot C, Brion F, Beaudouin R.   +3 more
europepmc   +1 more source

Monte Carlo Simulation in Environmental Risk Assessment--Science, Policy and Legal Issues [PDF]

, 1998
Dr. Poulter notes that agencies should anticipate judicial requirements for justification of Monte Carlo simulations and, meanwhile, should consider, e.g., whether their use will make risk assessment policy choices more opaque or ...
Poulter, Susan R.
core   +1 more source

An Application of a Physiologically Based Pharmacokinetic Approach to Predict Ceftazidime Pharmacokinetics in a Pregnant Population

Pharmaceutics
Physiological changes during pregnancy can alter maternal and fetal drug exposure. The objective of this work was to predict maternal and umbilical ceftazidime pharmacokinetics during pregnancy.
Khaled Abduljalil, Iain Gardner, Masoud Jamei   +2 more
doaj   +1 more source

Health Risk Assessment in Children Occupationally and Para-Occupationally Exposed to Benzene Using a Reverse-Translation PBPK Model. [PDF]

Int J Environ Res Public Health, 2023
Pech K, Pérez-Herrera N, Vértiz-Hernández ÁA, Lajous M, Farías P.   +4 more
europepmc   +1 more source

A PBPK model to evaluate zebrafish eleutheroembryos' actual exposure: bisphenol A and analogs' (AF, F, and S) case studies. [PDF]

Environ Sci Pollut Res Int, 2023
Billat PA, Brochot C, Brion F, Beaudouin R.   +3 more
europepmc   +1 more source

Global sensitivity analysis of Open Systems Pharmacology Suite physiologically based pharmacokinetic models

CPT: Pharmacometrics & Systems Pharmacology
Sensitivity analyses are important components of physiologically based pharmacokinetic (PBPK) model development and are required by regulatory agencies for PBPK submissions.
Abdulkarim Najjar, Abdullah Hamadeh, Sophia Krause, Andreas Schepky, Andrea Edginton   +4 more
doaj   +1 more source

Physiologically Based Pharmacokinetic (PBPK) Model-Informed Dosing Guidelines for Pediatric Clinical Care: A Pragmatic Approach for a Special Population. [PDF]

Paediatr Drugs, 2023
Freriksen JJM, van der Heijden JEM, de Hoop-Sommen MA, Greupink R, de Wildt SN.   +4 more
europepmc   +1 more source

[[alternative]]Statistical Analysis on Environmental Risk Assessment Using Pharmacokinetic Physiologically-based Model [PDF]

計畫編號：NSC91-2118-M032-001研究期間：200208~200307研究經費：434,000[[sponsorship ...
陳主智
core  

Refinement and calibration of a human PBPK model for the plasticiser, Di-(2-propylheptyl) phthalate (DPHP) using in silico, in vitro and human biomonitoring data. [PDF]

Front Pharmacol, 2023
McNally K, Loizou G.
europepmc   +1 more source

A PBPK model describing the pharmacokinetics of γ-HBCD exposure in mice. [PDF]

Toxicol Appl Pharmacol, 2021
Emond C, DeVito MJ, Birnbaum LS.
europepmc   +1 more source