Results 151 to 160 of about 12,447 (257)

In Silico Dosimetry Study of Tc99m-Tetrofosmin in Children Using a Novel PBPK Model in Humans Built from SPECT Imaging Data. [PDF]

Pharm Res, 2023
Kaikousidis C, Dokoumetzidis A.
europepmc   +1 more source

Modeling and Simulation of Triclosan Kinetics and Distribution in Humans Using a PBPK Model [PDF]

, 2015
Andreassen, Monica, Dirven, Hubert, Husøy, Trine, Lie, Bernt, Maharjan, Samee, Sharma, Roshan   +5 more
core   +4 more sources

Development, testing, parameterisation, and calibration of a human PBPK model for the plasticiser, di-(2-ethylhexyl) terephthalate (DEHTP) using in silico, in vitro and human biomonitoring data. [PDF]

Front Pharmacol, 2023
McNally K, Sams C, Hogg A, Loizou G.
europepmc   +1 more source

Using available in vitro metabolite identification and time course kinetics for β-chloroprene and its metabolite, (1-chloroethenyl) oxirane, to include reactive oxidative metabolites and glutathione depletion in a PBPK model for β-chloroprene. [PDF]

Front Pharmacol, 2023
Campbell JL, Clewell HJ, Van Landingham C, Gentry PR, Andersen ME.   +4 more
europepmc   +1 more source

[[alternative]]Statistical Analysis on Environmental Risk Assessment Using Pharmacokinetic Physiologically-based Model [PDF]

計畫編號：NSC91-2118-M032-001研究期間：200208~200307研究經費：434,000[[sponsorship ...
陳主智
core  

Human PBPK Modeling

This deliverable will report the final development of the human PBPK models developed within ...
openaire   +1 more source

Cluster Gauss-Newton method analyses of PBPK model parameter combinations of coproporphyrin-I based on OATP1B-mediated rifampicin interaction studies. [PDF]

CPT Pharmacometrics Syst Pharmacol, 2022
Yoshikado T, Aoki Y, Mochizuki T, Rodrigues AD, Chiba K, Kusuhara H, Sugiyama Y.   +6 more
europepmc   +1 more source

A PBPK model recapitulates early kinetics of anti-PEG antibody-mediated clearance of PEG-liposomes. [PDF]

J Control Release, 2022
Talkington AM, McSweeney MD, Wessler T, Rath MK, Li Z, Zhang T, Yuan H, Frank JE, Forest MG, Cao Y, Lai SK.   +10 more
europepmc   +1 more source

[[alternative]]Parameters Estimation of Physiologically-Based Pharmacokinetic Model Considering Dynamic Models [PDF]

計畫編號：NSC92-2118-M032-002研究期間：200308~200407研究經費：434,000[[sponsorship ...
陳主智
core  

Development of a Pregnancy-Specific Physiologically Based Pharmacokinetics (PBPK) Model for Aspirin. [PDF]

CPT Pharmacometrics Syst Pharmacol
Collins-Smith A, Kammala AK, Phelps MA, Wang XM, Menon R, Costantine MM.   +5 more
europepmc   +1 more source