Comparison of dermal and inhalation routes of entry for organic chemicals [PDF]
The quantitative comparison of the chemical concentration inside the body as the result of a dermal exposure versus an inhalation exposure is useful for assessing human health risks and deciding on an appropriate protective posture.
Clewell, Harvey J., III +2 more
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Physiologically Based Pharmacokinetic (PBPK) Model to Predict the Magnitude of Drug-Drug Interaction Between Fezolinetant and CYP1A2 Inhibitors. [PDF]
J Clin PharmacolChoules MP +4 more
europepmc +1 more source
Minimal brain PBPK model to support the preclinical and clinical development of antibody therapeutics for CNS diseases. [PDF]
J Pharmacokinet Pharmacodyn, 2021 Bloomingdale P +7 more
europepmc +1 more source
Development of a PBPK model of psilocybin/psilocin from Psilocybe cubensis (magic mushroom) in mice, rats, and humans. [PDF]
Sci RepThaoboonruang N +3 more
europepmc +1 more source
Modeling of Blood Lead Levels in Astronauts Exposed to Lead from Microgravity-Accelerated Bone Loss [PDF]
Human exposure to lead has been associated with toxicity to multiple organ systems. Studies of various population groups with relatively low blood lead concentrations (
Garcia, H., James, J., Tsuji, J.
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Editorial: Exploring Maternal-Fetal Pharmacology Through PBPK Modeling Approaches
Frontiers in Pediatrics, 2022 André Dallmann +2 more
openaire +3 more sources
Genotype, Ethnicity, and Drug-Drug Interaction Modeling as Means of Verifying Transporter Biomarker PBPK Model: The Coproporphyrin-I Story. [PDF]
CPT Pharmacometrics Syst PharmacolUjihira Y +3 more
europepmc +1 more source
A comprehensive physiologically based pharmacokinetic (PBPK) model for nicotine in humans from using nicotine-containing products with different routes of exposure. [PDF]
Sci Rep, 2022 Rostami AA +9 more
europepmc +1 more source
Sorafenib in mice - A Pharmacokinetic study [PDF]
, 2015 Abbiati, ROBERTO ANDREA +3 more
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