Protective Effects and Mechanisms of Dendrobium nobile Lindl. Alkaloids on PC12 Cell Damage Induced by Aβ 25-35. [PDF]
Behav Neurol, 2021 Liu Y, Pi T, Yang X, Shi J.
europepmc +1 more source
Cell Death in Neurodegenerative Diseases: Molecular Mechanisms and Therapeutic Targets
MedComm, Volume 7, Issue 9, September 2026.Regulated cell death pathways, including apoptosis, necroptosis, pyroptosis, ferroptosis, and autophagy‐dependent cell death, interact with mitochondrial dysfunction, proteostasis failure, lysosomal stress, glial remodeling, and neuroinflammation across major neurodegenerative diseases.
Tianjiao Li +3 more
wiley +1 more source
Journal of Peptide Science, Volume 32, Issue 9, September 2026.Site‐specifically modified α‐synuclein containing DOPA or phosphorylation was prepared by ligation of a bacterially expressed N‐terminal polypeptide and a synthetic C‐terminal modified peptide. ABSTRACT α‐Synuclein (αSyn) is a major component of pathogenic Lewy bodies and Lewy neurites and is closely associated with Parkinson's disease.
Tatsuhito Matsuo +7 more
wiley +1 more source
Construction of differential expression plasmids of NGF to detect its influence on PC12 cell neuronal differentiation. [PDF]
Exp Ther Med, 2021 Liu Y +5 more
europepmc +1 more source
FASEB BioAdvances, Volume 8, Issue 9, September 2026.Supraphysiological 25(OH)D3 and calcipotriol induced ROS accumulation or redox disturbance, increased mitochondrial membrane depolarization, reduced antioxidant enzyme activity, and caused apoptotic cell death in HeLa cells. ABSTRACT Cervical cancer remains a major global health challenge, necessitating continued advances in therapeutic strategies ...
Hoi Ching Cherry Chan +5 more
wiley +1 more source
SET domain containing 7 promotes oxygen-glucose deprivation/reoxygenation-induced PC12 cell inflammation and oxidative stress by regulating Keap1/Nrf2/ARE and NF-κB pathways. [PDF]
Bioengineered, 2022 Pan X, Fan J, Peng F, Xiao L, Yang Z.
europepmc +1 more source
The trk proto-oncogene rescues NGF responsiveness in mutant NGF-nonresponsive PC12 cell lines.
Cell, 1991 D. Loeb +5 more
semanticscholar +1 more source
Aging Cell, Volume 25, Issue 9, September 2026.Neuronal senescence‐like states arise from convergent intrinsic and disease‐associated stressors and are linked to persistent dysfunction, SASP‐like signaling, and altered glial interactions. Because no single marker is definitive in post‐mitotic neurons, multimarker and context‐dependent frameworks are required to define their role in ...
Miraj Ud Din Momand +2 more
wiley +1 more source
Slit2/Robo Signaling Restores Diabetic Erectile Function via Neurovascular Remodeling
Andrology, Volume 14, Issue 6, Page 1831-1846, September 2026.ABSTRACT Background Diabetes mellitus‐induced erectile dysfunction (DMED) is a common and debilitating vascular‐neurogenic complication of diabetes. The poor responsiveness of DMED patients to phosphodiesterase type‐5 inhibitors underscores the need for therapies capable of restoring both endothelial integrity and cavernous nerve function.
Sen Fu +7 more
wiley +1 more source
Differential Activation of Pro-Survival Pathways by NIX/BNIP3L: An Expression-Level-Dependent Mechanism Governing PC12 Cell Fate During H<sub>2</sub>O<sub>2</sub>-Induced Oxidative Stress. [PDF]
Biology (Basel)Ge F +7 more
europepmc +1 more source