Results 141 to 150 of about 17,065,304 (244)

Optimization of Extraction Process and Neuroprotective Activities of Flavonoids from Mentha haplocalyx Briq. with Subcritical Water

Shipin gongye ke-ji
Objective: To optimize the subcritical water extraction process for flavonoids from Mentha haplocalyx Briq. (mint) and assess the mitigating effects of peppermint flavonoids on H2O2-induced adrenal pheochromocytoma (PC12 cell) injury in rats.
Qingqing ZHANG, Mengjiao ZHANG, Yiming MA, Xueyi CAI   +3 more
doaj   +1 more source

Mixture of Tomato and Lemon Extracts Synergistically Prevents PC12 Cell Death from Oxidative Stress and Improves Hippocampal Neurogenesis in Aged Mice. [PDF]

Foods, 2022
Hong JY, Ban JJ, Quan QL, Eom JE, Shin HS, Chung JH.   +5 more
europepmc   +1 more source

DHA ameliorates MeHg‑induced PC12 cell apoptosis by inhibiting the ROS/JNK signaling pathway. [PDF]

Mol Med Rep, 2021
Zhang H, Wang S, Wang Y, Lu A, Hu C, Yan C.   +5 more
europepmc   +1 more source

Study on the Antidepressant Effect and Mechanism of Water Extract of Semiliquidambar cathayensis (WESC) Based on the GSK3β/NF‐κB Signaling Pathway

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Ultra‐high‐performance liquid chromatography coupled with quadrupole time‐of‐flight mass spectrometry (UPLC‐Q‐TOF‐MS) was used to characterize the chemical constituents of the water extract of Semiliquidambar cathayensis (WESC). Network pharmacology and molecular docking were applied to screen core active components and potential targets.
Li Yang, Junhui He, Dongmei Li, Yi Li, Qibiao Su, Hongning Liang, Jiantong Yuan, Kedao lai, Guining Wei   +8 more
wiley   +1 more source

SB203580 promote EGF-stimulated early morphological differentiation in PC12 cell through activating ERK pathway [PDF]

, 2001
MAP kinases have important role in PC12 cell differentiation, since the activities of both extracellular regulated protein kinase (ERK) and p38 have been indicated as necessary signal for PC12 cell differentiation.
Li, Y. Q., Liu, K., 韩家淮, Han, J. H., New, L. G., Ge, B. X., Mansbridge, J., Zhong, H. Y.   +7 more
core  

Endophytic Fungi Natural Factories of Novel Bioactive Compounds

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
This review provides a systematic analysis of 242 natural products isolated from 42 genera of endophytic fungi, highlighting their remarkable structural diversity and broad spectrum of biological activities . ABSTRACT Endophytic fungi represent a prolific and chemically diverse source of novel specialized metabolites with significant pharmacological ...
Dilmurod Murodullayev, Jakhongir Movlanov, Liu Wei, Wei Liu, Maksud Isokov, Santosh Kumar Bose, Fazliddin Kobilov, Zamira Djumayeva, Buston Islamov, Jamila Sherkulova, Zafar Matyakubov, Muniskhon Meylieva, Munisa Ergasheva, Diyor Abduraxmanov, Guozheng Huang, Hongchen Jiang, Kakhramon Davranov, Guohui Pan, Nigora Rustamova   +18 more
wiley   +1 more source

Metabolomics analysis of poly(l-lactic acid) nanofibers' performance on PC12 cell differentiation. [PDF]

Regen Biomater, 2021
Su X, Huang Y, Chen R, Zhang Y, He M, Lü X.   +5 more
europepmc   +1 more source

Dystrophin Dp71f associates with the beta1-integrin adhesion complex to modulate PC12 cell adhesion.

, 2006
Dystrophin Dp71 is the main product of the Duchenne muscular dystrophy gene in the brain; however, its function is unknown. To study the role of Dp71 in neuronal cells, we previously generated by antisense treatment PC12 neuronal cell clones with ...
Centeno, Federico, Cerna, Joel, García-Sierra, Francisco, Efrain Garrido, Doris Cerecedo, Federico Centeno, Bulmaro Cisneros, Garrido, Efrain, Francisco García-Sierra, Cisneros, Bulmaro, Ortega, Arturo, Joel Cerna, Mornet, Dominique, Dominique Mornet, Cerecedo, Doris, Arturo Ortega   +15 more
core   +1 more source

Dual miRNA‐Mediated Axes Act in Concert in the Antioxidant Action of Eicosapentaenoic Acid: let‐7c‐3p/TFAM Drives Mitochondrial Biogenesis While miR‐34c‐5p/SIRT1 Potentiates Enzymatic Defenses

Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT Previous transcriptomic analysis revealed that eicosapentaenoic acid (EPA) alters miRNA expression in HepG2 cells. Two key miRNA‐mRNA axes mediating EPA's antioxidant effects were identified. EPA was found to downregulate let‐7c‐3p, which directly targets mitochondrial transcription factor A (TFAM).
Haiqi Wang, Yanqi Lin, Yuanyuan Li, Xiaowen Wu, Jingyu Lin, Shiying Huang, Guiling Li   +6 more
wiley   +1 more source

Structural Characterization and UVB Irradiation Protective Effect of the Polysaccharide From Tremella fuciformis After Microbial Fermentation

Food Frontiers, Volume 7, Issue 5, September 2026.
ABSTRACT Tremella fuciformis is an edible mushroom rich in bioactive polysaccharides. In this study, T. fuciformis was extracted by citric acid under high temperature and high‐pressure (121°C, 0.1 MPa), followed by fermentation with Saccharomyces cerevisiae CH006 and Thermus thermophilus HB27.
Xin‐Yan He, Jun‐Qiao Wang, Yi‐Qi Lin, Sih‐Yu Chu, Wen‐Xin Wang, Xuan‐Han Xiao, Yu‐Ke Hou, Xiao‐Feng Qiu, Shao‐Ping Nie, Zhi‐Jiang Wang, Huan‐Yu Liu   +10 more
wiley   +1 more source