Effects of Tributyltin Chloride on Human Neuronal Differentiation and Mice Brain Development
Environmental Toxicology, Volume 41, Issue 10, Page 906-921, October 2026.ABSTRACT According to the developmental origins of health and disease hypothesis, perinatal exposure to an environmental toxicant during the development of the nervous system could cause a permanent cellular modification that may promote the appearance of neurodegenerative diseases at an older age.
Ester López‐Gallardo +10 more
wiley +1 more source
PCBP-1 Regulates the Transcription and Alternative Splicing of Inflammation and Ubiquitination-Related Genes in PC12 Cell. [PDF]
Front Aging Neurosci, 2022 Yusufujiang A +5 more
europepmc +1 more source
Aging Cell, Volume 25, Issue 10, October 2026.Mitochondrial fission‐fusion imbalance contributes to age‐related cardio‐cerebral diseases like Alzheimer's disease, Parkinson's disease, Cerebral Infarction, Arteriosclerosis, Myocardial Infarction, Cardiac valve disease, Hypertension, and Cardiomyopathy. This review summarizes its regulatory mechanisms and interventions.
Yuyao Yin, Zijian Li
wiley +1 more source
Neuroprotection of Gastrodia elata polyphenols against H2O2-induced PC12 cell cytotoxicity by reducing oxidative stress. [PDF]
Front Pharmacol, 2022 Tan W +8 more
europepmc +1 more source
Advanced Healthcare Materials, Volume 15, Issue 36, 25 September 2026.Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave +8 more
wiley +1 more source
Protective Effects of Marine Alkaloid Neolamellarin A Derivatives against Glutamate Induced PC12 Cell Apoptosis. [PDF]
Mar Drugs, 2022 Zhang K +5 more
europepmc +1 more source
Optimisation of a PC12 Cell-based In Vitro Stroke Model for Screening Potential Neuroprotective Agents [PDF]
, 2019 Aims/Objective: PC12 cells can be differentiated into a neuronal phenotype with nerve growth factor (NGF), and were widely used as an in vitro stroke model for screening neuroprotective agents.
Chua, P.F., Lim, William W.K.
core
Effects of OGD on the morphology, cell apoptosis, and viability of PC12 cells.
, 2018 PC12 cells were cultured under OGD for 0, 1, 2, 4, 6, 8, 10, or 12 h and then cultured under normal conditions for 24 h. Cell morphology, apoptosis, and viability were evaluated. (A) PC12 cell morphology.
Yunfei Ma (1777753) +5 more
core +1 more source
Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives
Advanced Materials, Volume 38, Issue 51, 11 September 2026.Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi +4 more
wiley +1 more source
Protective Effects of Morphine on Serum Deprivation-induced Cell Death in PC12 Cells
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2013 BACKGROUND AND OBJECTIVE: Morphine is the most effective pain-relieving drugs in the management of pain. Morphine modulates survival and apoptosis of neural and tumoral cells.
H Zhaleh +3 more
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