Results 111 to 120 of about 17,065,304 (244)

Bioactive peptides in cancer and inflammation: Mechanisms, model systems and clinical translation

open access: yesClinical and Translational Discovery, Volume 6, Issue 5, October 2026.
Bioactive peptides (BAPs) derived from host, marine, insect, plant and synthetic sources share cationic, amphipathic structures adopting α‐helical, β‐sheet or cyclic conformations. These features underlie anti‐cancer effects, including membrane disruption, apoptosis and cell‐cycle arrest, anti‐metastatic activity, reduced invasion and migration, and ...
Najwa Doha   +4 more
wiley   +1 more source

Gypenosides Attenuates CORT-Induced Ferroptosis via Inhibiting TNF-α/NF-κB Signaling Pathway in PC12 Cells

open access: yesMolecules
Chronic stress can lead to nervous system dysfunction and depression-like behaviors in animals. Gypenosides can improve chronic stress-induced neuronal damage, but the protective mechanism remains poorly understood.
Lingling Dai   +7 more
doaj   +1 more source

In vitro effects of fetal rat cerebrospinal fluid on viability and neuronal differentiation of PC12 cells

open access: yesFluids and Barriers of the CNS, 2012
Background Fetal cerebrospinal fluid (CSF) contains many neurotrophic and growth factors and has been shown to be capable of supporting viability, proliferation and differentiation of primary cortical progenitor cells.
Nabiuni Mohammad   +5 more
doaj   +1 more source

Lactate metabolism and protein lactylation in programmed cell death: From novel mechanism to therapeutic strategies in human diseases

open access: yesClinical and Translational Medicine, Volume 16, Issue 10, October 2026.
This review highlights protein lactylation as a metabolic‐epigenetic regulator linking lactate reprogramming to programmed cell death. By modulating histone and non‐histone targets, lactylation reshapes cell fate decisions and represents a promising biomarker and therapeutic target in human diseases.
Yue Chen   +8 more
wiley   +1 more source

Interaction of gold nanoparticles with neurons

open access: yes, 2013
In the last few decades, advances in nanotechnology have resulted in the production and use of inorganic nanoparticles (NPs). These NPs have been used commercially for a range of applications, particularly in the biomedical field, based on their ...
Christofidou, A.
core   +1 more source

The TRPM2–PARP‐1 Axis Involvement in Bisphenol A and Nonylphenol‐Induced Ferroptosis in Trigeminal Ganglion Cells

open access: yesJournal of Applied Toxicology, Volume 46, Issue 10, Page 3660-3674, October 2026.
ABSTRACT Environmental contaminants like bisphenol A (BPA) and nonylphenol (NP) are recognized neurotoxicants; however, the molecular mechanisms underlying their impact on sensory ganglia, specifically the trigeminal ganglion (TG), remain critically underexplored.
Betül Yazğan   +3 more
wiley   +1 more source

Effect of Electrical and Electromechanical Stimulation on PC12 Cell Proliferation and Axon Outgrowth. [PDF]

open access: yesFront Bioeng Biotechnol, 2021
Xu K   +6 more
europepmc   +1 more source

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