Results 101 to 110 of about 17,065,304 (244)
PLoS ONE, 2018 Leonurine has been reported to play an important role in ameliorating cognitive dysfunction, inhibiting ischemic stroke, and attenuating perihematomal edema and neuroinflammation in intracerebral hemorrhage.
Jiao Li +5 more
doaj +1 more source
Phenolic Glycosides From Ficus erecta and Their Anti-Inflammatory and Neuroprotective Activities. [PDF]
Chem BiodiversFive new phenolic glycosides, ficuserectosides A‐E (1–5), along with three known congeners (6–8) were isolated and identified from Ficus erecta. Compounds 5 and 8 protect PC12 cells from oxidative damage by decreasing reactive oxygen species (ROS) and increasing glutathione (GSH), highlighting their potential as neuroprotective leads.
Wu W, Hu R, Li G, Luo Q, Jin A.
europepmc +2 more sources
British Journal of Pharmacology, EarlyView.Disruption of intracellular ionic homeostasis is a convergent pathological feature across diverse neurological injuries and disorders, including ischaemic and haemorrhagic stroke, hypoxic–ischaemic brain injury, traumatic brain injury, epilepsy and brain tumour.
Xinyang Zhang +5 more
wiley +1 more source
Assessing the effectiveness of Sri Lankan marine protected areas: Challenges and recommendations
Conservation Science and Practice, EarlyView.We evaluated the biodiversity conservation effectiveness of 32 zones of Sri Lankan marine protected areas (MPA) and found that most are currently insufficiently protected. Threats to MPAs were not uniform, with harmful dredging/dumping, anchoring, fishing, and non‐extractive activities identified as major pressures affecting different sets of MPAs.
Barbora Winterová +3 more
wiley +1 more source
The effect of TRTS on cell proliferation of PC12 cells.
, 2015 (A–L) PC12 cells in cell growth medium were exposed to TRTS at two different temperatures for 18 h/day, or left untreated for 7 days. During TRTS, phase-contrast images were captured on day 0 (A, E, and I), day 3 (B, F, and J), day 5 (C, G, and K), and ...
Kazumi Mori (724962) +11 more
core +1 more source
Characterization of Elementary Ca2+ Release Signals in NGF-Differentiated PC12 Cells and Hippocampal Neurons [PDF]
, 1999 Elementary Ca2+ release signals in nerve growth factor– (NGF-) differentiated PC12 cells and hippocampal neurons, functionally analogous to the “Ca2+ sparks” and “Ca2+ puffs” identified in other cell types, were characterized by confocal microscopy. They
Koizumi, Schuichi +9 more
core +1 more source
Physiological media and oxygen levels modulate cancer hallmarks in cultured breast cancer cells
The FEBS Journal, EarlyView.MCF7 breast cancer cells were cultured in standard conditions (18% O2 and DMEM) and physiological conditions (5% O2 and Plasmax, a medium modeled after the human plasma metabolome). A combined transcriptomic and proteomic approach was used to identify gene expression signatures at the mRNA and protein levels upstream of functional enrichment analyses ...
Jacob E. Wiebe +5 more
wiley +1 more source
Role of PARP-1 in mitochondroal DNA damage induced by rotenone in PC12 cells
Di-san junyi daxue xuebao, 2019 Objective To explore the effect of poly (ADP-ribose) polymerase-1 (PARP-1) on mitochondrial DNA (mtDNA) damage induced by rotenone in rat adrenal medulla pheochromocytoma PC12 cells. Methods PC12 cells were treated with various dose of rotenone.
XIAO Jingsong, HOU Guizhong, SAI Yan
doaj +1 more source
Tetrahydrobiopterin Enhances Apoptotic PC12 Cell Death following Withdrawal of Trophic Support*
Journal of Biological Chemistry, 2001 (6R)-Tetrahydro-l-biopterin (BH4) is the rate-limiting cofactor in the production of catecholamine and indoleamine neurotransmitters and is also essential for the synthesis of nitric oxide by nitric-oxide synthase.
P. Anastasiadis +4 more
semanticscholar +1 more source
Periodontology 2000, EarlyView.Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad +6 more
wiley +1 more source