Results 81 to 90 of about 17,065,304 (244)
Medicine Bulletin, EarlyView.ABSTRACT β‐Aminoisobutyric acid (BAIBA) is an exercise‐responsive myokine/metabolite released by skeletal muscle and has attracted increasing interest as a potential exercise mimetic and therapeutic candidate in preclinical research. BAIBA acts locally in skeletal muscle and can also reach distal organs through the circulation, contributing to the ...
Hao‐Zhe Wang +5 more
wiley +1 more source
Cell Transplantation, 1997 The PC12 pheochromocytoma tumor cell line is derived from a rat adrenal medullary tumor and secretes dopamine. We have previously reported that grafted microencapsulated PC12 cells using agarose and poly(styrene sulfonic acid) survived in the xenogeneic ...
Takeshi Ono M.D. +6 more
doaj +1 more source
Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges
Neuroprotection, EarlyView.Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi +5 more
wiley +1 more source
, 1996 To establish whether protein kinase C was involved in the nuclear events underlying cell differentiation and proliferation, rat pheochromocytoma PC12 cells, serum-starved for 24 h, were treated with either differentiating doses of nerve growth factor or ...
PREVIATI, Maurizio +8 more
core +2 more sources
NADPH oxidase in PC12 cell differentiation and apoptosis [PDF]
, 2008 Neuronal differentiation is an important process during human development and regenerative medicine. One factor linked to differentiation of neurons in vivo as well as in vitro is the generation of reactive oxygen species (ROS).
Begdache, Lina
core +3 more sources
Mechanistische Auswirkungen der schwedischen APP-Mutation und des Caspase-3-gespalteten c-terminalen Presenilin-Fragments auf die neurotoxischen Effektive von Beta Amyloid [PDF]
, 2005 Alzheimer’s disease (AD) is the most common neurodegenerative disorder world wide, causing presenile dementia and death of millions of people. During AD damage and massive loss of brain cells occur.
Azinheiro Marques, Celio
core
Phytotherapy Research, EarlyView.Research landscape and mechanistic insights into natural medicines for Alzheimer's disease. ABSTRACT Natural medicines have been widely investigated for Alzheimer's disease (AD), but the development of this field and the relationship between bibliometric themes and experimental evidence remain insufficiently characterized.
Maoning Wang +8 more
wiley +1 more source
Cell Transplantation, 1993 Two PC12 cell-derived lines have been studied following encapsulation into polymer-based hollow fibers with respect to secreted catecholamines and their metabolites.
Mark P. Lavoie +7 more
doaj +1 more source
BMC Complementary Medicine and Therapies, 2020 Background The embryos of Nelumbo nucifera Gaertn seeds, lianzixin, are used in China as food and traditional herbal medicine. Principal therapeutic indications are insomnia, anxiety and pyrexia.
Jingjing Chen +5 more
doaj +1 more source
Responsive Materials, EarlyView.This review presents the structure and transport routes of the blood‐brain barrier, summarizes the ischemic stroke pathophysiological cascade, and discusses the BBB‐crossing mechanisms and multitarget therapeutic effects of carbon dots, demonstrating their promising theranostic potential for ischemic stroke.
Yanhan Huang +6 more
wiley +1 more source