Maternally Expressed Gene 3 (MEG3) Enhances PC12 Cell Hypoxia Injury by Targeting MiR-147 [PDF]
Cellular Physiology and Biochemistry, 2017 Background/Aims: Cerebral ischemia often leads to breakdown of blood–brain barrier (BBB) and vasogenic edema. It remains to be established whether MEG3 is responsible for the hypoxic damage in neural cells.
Lili Han +4 more
doaj +2 more sources
Chinese Angelica Polysaccharide (CAP) Alleviates LPS-Induced Inflammation and Apoptosis by Down-Regulating COX-1 in PC12 Cells [PDF]
Cellular Physiology and Biochemistry, 2018 Background/Aims: Chinese angelica polysaccharide (CAP) is the main effective ingredient of angelica sinensis and exerts anti-inflammatory and anti-apoptotic effects on many diseases.
Yunjie Xie +5 more
doaj +2 more sources
Current Situation of PC12 Cell Use in Neuronal Injury Study [PDF]
, 2015 The nervous system diseases are easy to get and hard to cure. The mechanism is bound up with nervous cells injure, so it’s significant to study medicine protect nervous cells injure. We need find an ideal model to study these diseases.
Xiao-Hua Duan +5 more
semanticscholar +2 more sources
Evaluation of PC12 Cell Neural Differentiation on Graphene Coated ITO Microchips [PDF]
, 2020 In this study, the impact of graphene on neuronal differentiation of PC12 cells into neuron-like cells was evaluated in conjunction with electrical stimuli.
Mustafa, Sen +3 more
core +1 more source
MiR-103 alleviates autophagy and apoptosis by regulating SOX2 in LPS-injured PC12 cells and SCI rats [PDF]
Iranian Journal of Basic Medical Sciences, 2018 Objective(s): Recent studies revealed that microRNAs (miRNAs) may play crucial roles in the responses and pathologic processes of spinal cord injury (SCI).
Guowei Li +5 more
doaj +1 more source
BioMed Research International, 2020 Objective This study is aimed at studying the effect of quercetin on the Alzheimer disease cell model induced by Aβ25-35 in PC12 cells and its mechanism of action. Methods The AD cell model was established by Aβ25-35.
Xinjun Yu, Yi-Cai Li, X. Mu
semanticscholar +1 more source
Rab3D is critical for secretory granule maturation in PC12 cells. [PDF]
, 2013 Neuropeptide- and hormone-containing secretory granules (SGs) are synthesized at the trans-Golgi network (TGN) as immature secretory granules (ISGs) and complete their maturation in the F-actin-rich cell cortex.
Sharon A. Tooze (391543) +36 more
core +1 more source
Memantine inhibits 6-OHDA-induced apoptosis PC12 cells via the Nurr77 and caspase pathway
Asian Pacific Journal of Tropical Medicine, 2019 Objective: To investigate the effect of memantine on Parkinson’s disease cell models. Methods: Parkinson’s disease cell models were established using PC12 cells incubated with 6-hydroxydopamine (6-OHDA).
Wei Wu +5 more
doaj +1 more source
Genistein and daidzein reduced chlorpyrifos induced damage in PC12 cell
Oil Crop Science, 2020 The present study preliminarily evaluated neurotoxicity injuries induced by chlorpyrifos in PC12 cell, which were used as a model for nervous cell system.
Yu Gao +4 more
doaj +1 more source
Characterization of PC12 Cell Subclones with Different Sensitivities to Programmed Thermal Stimulation. [PDF]
Int J Mol Sci, 2020 Neuritogenesis is the process underling nervous system regeneration; however, optimal extracellular signals that can promote neuronal regenerative activities require further investigation.
Kudo TA +7 more
europepmc +2 more sources