Neferine inhibits Aβ1-42-induced PC12 cell injury through regulating the expression of miR-29a-3p/AQP4 [PDF]
Jichu yixue yu linchuang, 2020 Objective To explore the role and molecular mechanism of Neferine (Nef) on PC12 cells injury induced by Aβ1-42. Methods PC12 cells were divided into control group, model group(4 μg/mL Aβ1-42 cultured for 24 h) and low, medium and high-dose neferine ...
ZENG Li-min, LU Zhao-hui, ZHOU Li-ping, ZHU Chao-xia
doaj
Microconical silicon structures influence NGF‐induced PC12 cell morphology
Journal of Tissue Engineering and Regenerative Medicine, 2015 Micro‐and nanofabrication techniques provide the opportunity to develop new types of cell culture platform, where the effect of various topographical cues on cellular functions such as proliferation and differentiation can be studied. In this study, PC12
C. Simitzi +4 more
semanticscholar +1 more source
Low-dose levodopa protects nerve cells from oxidative stress and up-regulates expression of pCREB and CD39. [PDF]
PLoS ONE, 2014 OBJECTIVE: This study aimed to investigate the influence of low-dose levodopa (L-DOPA) on neuronal cell death under oxidative stress. METHODS: PC12 cells were treated with L-DOPA at different concentrations. We detected the L-DOPA induced reactive oxygen
Shi-Ying Zhong +5 more
doaj +1 more source
Introduction of Macromolecules into Bovine Adrenal Medullary Chromaffin Cells and Rat Pheochromocytoma Cells (PC12) by Permeabilization with Streptolysin O: Inhibitory Effect of Tetanus Toxin on Catecholamine Secretion [PDF]
, 1989 Conditions are described for controlled plasma membrane permeabilization of rat pheochromocytoma cells (PC12) and cultured bovine adrenal chromaffin cells by Streptolysin O (SLO).
Ahnert-Hilger, G. +3 more
core +1 more source
miR-96-5p is involved in alcohol-induced apoptosis in PC12 cells via negatively regulating TAp73
PLoS ONE, 2023 Objective The present study opted for the adrenal phaeochromocytoma (PC12) cell line to frame a neuronal injury model induced by alcohol exposure in vitro, aiming to probe whether TAp73 and miR-96-5p are involved in the neuronal injury process induced by
Bin Yang +8 more
doaj +2 more sources
Cell stress & chaperones (Print), 2014 Microglia play an important role in neuronal protection and damage. However, the molecular and cellular relationship between microglia and neurons is unclear. We carried out a prospective study to detect that activation of BV2 microglia induced PC12 cell
Xiao-Jing Dai +6 more
semanticscholar +1 more source
Cholesterol transport from late endosomes to the Golgi regulates t-SNARE trafficking, assembly, and function [PDF]
, 2011 Cholesterol regulates plasma membrane (PM) association and functioning of syntaxin-4 and soluble N-ethylmaleimide-sensitive fusion protein 23 (SNAP23) in the secretory pathway.
Enrich Bastús, Carles +25 more
core +1 more source
Study on Impact Resistance of PC12 Cells
Journal of Biomechanical Science and Engineering, 2010 In this study, the effects of a dynamic strain in the cytotoxicity and mortality of the PC12 cell line were evaluated by using impact experiment with huge acceleration.
Yuelin ZHANG +5 more
doaj +1 more source
Natural Product Communications, 2021 Background Oleanolic acid (OA) has notable anti-inflammatory and anti-tumor effects, but the role of OA in cerebral ischemia-reperfusion injury (CIRI) has not been reported so far.
Song Gu
doaj +1 more source
Effects of curcumin on the proliferation and invasiveness of pheochromocytoma cell line PC12 [PDF]
Jichu yixue yu linchuangObjective To investigate the effects of curcumin on the proliferation, migration, invasion, and apoptosis of pheochromocytomacell line PC12. Methods PC12 cells were incubated with different concentrations of curcumin.
ZHANG Wenqian, ZHOU Yue, REN Weidong, TONG Anli
doaj +1 more source