Results 31 to 40 of about 17,065,304 (244)
Heliyon, 2023 This study aimed to investigate the effects of mesenchymal stem cell exosomes loaded with Fe3O4 magnetic particles (Fe3O4@ MSC-exo) on the survival and neural differentiation of PC12 cells. Exosomes were separated from Fe3O4 magnetic nanoparticles-primed
Yong Xie +4 more
doaj +1 more source
Neural cell adhesion molecules in rat endocrine tissues and tumor cells: distribution and molecular analysis [PDF]
, 1993 The adhesive properties of neural cell adhesion molecules (NCAMs) can be modified by alternative splicing of the primary transcript or posttranslational modifications.
Lahr, G. +5 more
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Neuromodulation: Technology at the Neural Interface, EarlyView., 2021 Abstract Objectives Acute cerebral ischemia is characterized by several pathological processes evolving during time, which contribute to the final tissue damage. Secondary processes, such as prolonged inflammatory response, impaired mitochondrial function and oxidative stress, are responsible for the progression of brain injury to the peri‐infarct area,
Fioravante Capone +8 more
wiley +1 more source
Effect of hydrogen sulfide on PC12 cell injury induced by high ATP concentration [PDF]
, 2022 Purpose: To investigate the potential protective effect of hydrogen sulfide against neural cell damage induced by a high-concentration of adenosine triphosphate (ATP).Methods: PC12 cells were incubated with ATP in order to induce cell damage.
Luo, Hu +7 more
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Frontiers in OncologyIntroductionPheochromocytomas and paragangliomas (PPGLs) are associated with poor prognosis especially in patients with metastatic spread. This study aims to investigate the therapeutic potential of 131I-MIBG and the PARP inhibitor fluzoparib ...
Jieping Song +7 more
doaj +1 more source
Journal of Pharmacological Sciences, 2007 Bovine lactoferrin (bLf) is an iron-binding secretory protein present in breast milk, mucosal secretions, and the secondary granules of neutrophils. Although bLf has multiple functions, including antimicrobial and immunomodulatory activities, its effect ...
Toshiaki Ishii +6 more
doaj +1 more source
Evaluation of Reaction of Primate Brain to Grafted PC12 Cells
Cell Transplantation, 1999 Intrastriatal implantation of polymer-encapsulated PC12 cells, which constitute a dopaminergic cell line derived from rat pheochromocytoma, has proved useful for ameliorating parkinsonian symptoms in several kinds of animals.
Hideyuki Yoshida M.D. +6 more
doaj +1 more source
Possible Role of Interleukin-6 in PC12 Cell Death Induced by MPP+ and Tetrahydroisoquinoline
Journal of Pharmacological Sciences, 2003 : Interleukin (IL)-6 has been shown to protect neuronal cells from cell death induced by various stimulants. Although neuronal cells including PC12 cells were shown to produce IL-6, little is known about the effects of dopaminergic neurotoxins, 1,2,3,4 ...
Naoko Shimma +7 more
doaj +1 more source
, 2016 Oxidative stress and apoptosis contribute to neuronal degeneration in many neurodegenerative diseases such as Alzheimer’s disease. Glutamate is a major excitatory neurotransmitter in the central nervous system (CNS) and is considered responsible for the ...
Arezoo Rajabian +2 more
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Effects of chlorpyrifos and chlorpyrifos-methyl on the outgrowth of axon-like processes, tubulin, and GAP-43 in N2a cells [PDF]
, 2005 The aim of this work was to study the neurodegenerative effects of the organophosphate (OP) pesticides chlorpyrifos (CPF) and chlorpyrifos-methyl (CHM) on cultured mouse N2a neuroblastoma cells.
Sachana, M, Flaskos, J, Hargreaves, AJ
core +1 more source