Results 31 to 40 of about 4,447,834 (239)

Neural cell adhesion molecules in rat endocrine tissues and tumor cells: distribution and molecular analysis [PDF]

, 1993
The adhesive properties of neural cell adhesion molecules (NCAMs) can be modified by alternative splicing of the primary transcript or posttranslational modifications.
Lahr, G., Bucher, S., Wille, W., Gratzl, Manfred, Barthels, D., Mayerhofer, Artur   +5 more
core   +1 more source

Evaluation of Intracerebral Grafting of Dopamine-Secreting PC12 Cells into Allogeneic and Xenogeneic Brain

Cell Transplantation, 1997
The PC12 pheochromocytoma tumor cell line is derived from a rat adrenal medullary tumor and secretes dopamine. We have previously reported that grafted microencapsulated PC12 cells using agarose and poly(styrene sulfonic acid) survived in the xenogeneic ...
Takeshi Ono M.D., Isao Date, Takashi Imaoka, Tetsuro Shingo, Tomohisa Furuta, Shoji Asari, Takashi Ohmoto   +6 more
doaj   +1 more source

Neferine and lianzixin extracts have protective effects on undifferentiated caffeine-damaged PC12 cells

BMC Complementary Medicine and Therapies, 2020
Background The embryos of Nelumbo nucifera Gaertn seeds, lianzixin, are used in China as food and traditional herbal medicine. Principal therapeutic indications are insomnia, anxiety and pyrexia.
Jingjing Chen, Mimi Tang, Manhua Liu, Yueping Jiang, Bin Liu, Shao Liu   +5 more
doaj   +1 more source

The gut microbiota metabolite butyrate mitigates MPTP/MPP+‐induced Parkinson's disease by inhibiting the JAK2/STAT3 signaling pathway

Kaohsiung Journal of Medical Sciences, 2023
Butyrate (BU), a gut microbiota‐derived metabolite, has been reported to play a neuroprotective role in Parkinson's disease (PD). However, the specific molecular mechanism of BU has not been fully interpreted.
Li‐Li Ji, Ting‐Ting Huang, Lun‐Lin Mao, Yuan‐Feng Xu, Wen‐Ya Chen, Wei‐Wei Wang, Li‐Hui Wang   +6 more
doaj   +1 more source

Protective effects of components of the Chinese herb grassleaf sweetflag rhizome on PC12 cells incubated with amyloid-beta42

Neural Regeneration Research, 2015
The major ingredients of grassleaf sweetflag rhizome are β-asarone and eugenol, which can cross the blood-brain barrier and protect neurons. This study aimed to observe the neuroprotective effects and mechanisms of β-asarone and eugenol, components of ...
Zi-hao Liang, Xiao-hui Cheng, Zhi-gang Ruan, Han Wang, Shan-shan Li, Jing Liu, Guo-ying Li, Su-min Tian   +7 more
doaj   +1 more source

Chrysin, which targets PLAU, protects PC12 cells from OGD/R-stimulated damage through repressing the NF-κB signaling pathway

Regenerative Therapy, 2022
Cerebral ischemia reperfusion injury (CIRI) is a great challenge for the patients with brain ischemia, but its pathophysiological mechanism has not been clearly explored.
Ning Li, Ying Liu, Ju-Rong Li, Wen-Xue Zhang   +3 more
doaj   +1 more source

How does conserved dopamine neurotrophic factor protect against and rescue neurodegeneration of PC12 cells?

Neural Regeneration Research, 2017
Conserved dopamine neurotrophic factor protects and rescues dopaminergic neurodegeneration induced by 6-hydroxydopamine in vivo, but its potential value in treating Parkinson's disease remains controversial.
Jia-ming Mei, Chao-shi Niu
doaj   +1 more source

Molecular Aspects of Secretory Granule Exocytosis by Neurons and Endocrine Cells [PDF]

, 1994
Neuronal communication and endocrine signaling are fundamental for integrating the function of tissues and cells in the body. Hormones released by endocrine cells are transported to the target cells through the circulation.
MANFRED GRATZL, Gratzl, Manfred
core   +1 more source

Neurite length in PC12 cells.

, 2022
(a) The fluorescent images of PC12 cells stained with TRITC-conjugated phalloidin and DAPI. The images were gray-scale images with pseudo color, where the neurites were red, and the nuclei were blue.
Yan Huang (46805), Chen Meng (411751), Zequn Zhang (9921406), Zhigong Wang (4760226), Kun Hou (2433646), Xiaoying Lü (4760220)   +5 more
core   +1 more source

Protective Effect of Schisandrin on CORT-Induced PC12 Depression Cell Model by Inhibiting Cell Apoptosis In Vitro

Applied Bionics and Biomechanics, 2022
Background. In recent years, the incidence of depression is on the rise. Our paper proposed to study the protective effects of Schisandrin on CORT-induced PC12 depressive cell model and the underlying mechanisms. Methods. The in vitro models of PC12 were
Liu Yang, Yeqiu Wang, Lifeng An, Xinya Zhang, Jing Wang, Yi Wang, Ruyang Cheng, Chenxiang Li, Wei Ma   +8 more
doaj   +1 more source