Results 41 to 50 of about 36,872 (221)

Activation of the PI3K/mTOR pathway is involved in cystic proliferation of cholangiocytes of the PCK rat. [PDF]

open access: yesPLoS ONE, 2014
The polycystic kidney (PCK) rat is an animal model of Caroli's disease as well as autosomal recessive polycystic kidney disease (ARPKD). The signaling pathways involving the mammalian target of rapamycin (mTOR) are aberrantly activated in ARPKD.
Xiang Shan Ren   +6 more
doaj   +1 more source

Measuring PCK – Discussing the Assessment of PCK-related Achievement in Science Teacher Training

open access: yesProcedia - Social and Behavioral Sciences, 2015
AbstractPrimary school teachers often lack content (CK) and pedagogical content knowledge (PCK) in the domain of natural sciences. Therefore effective teacher training is needed and the outcomes have to be assessed. In this paper the validation of an assessment methodology is described as part of an interdisciplinary primary science teacher education ...
Kratz, Julia, Schaal, Steffen
openaire   +1 more source

Machine Learning‐Driven Variability Analysis of Process Parameters for Semiconductor Manufacturing

open access: yesAdvanced Intelligent Systems, EarlyView.
This research presents a machine learning approach that integrates nonlinear variation decomposition (NLVD) with statistical techniques to quantify the contribution of individual unit processes to performance and variance of figure of merit (FoM) at the LOT level.
Sinyeong Kang   +6 more
wiley   +1 more source

CoRes as tools for promoting pedagogical content knowledge of novice science teachers [PDF]

open access: yes, 2010
Expert science teachers possess a special blend of science content knowledge and pedagogical knowledge for teaching particular science topics to particular groups of students that is built up over time and experience. This form of professional knowledge,
Hume, Anne Christine
core   +1 more source

Compensation Response to Hepatic Gluconeogenesis via β‐Hydroxybutyrylation of FBP1 and PCK1 in Dairy Cows

open access: yesAnimal Research and One Health, EarlyView.
(1) Kbhb modification of FBP1 and PCK1 is involved in regulation of the gluconeogenesis pathway. (2) Kbhb of FBP1 and PCK1 is catalyzed by p300 and removed by HDACs. (3) BHB induced an increase in the enzymatic activity of FBP1 and PCK1 through Kbhb modification at the K43 site of FBP1 and the K191 site of PCK1.
DingPing Feng   +6 more
wiley   +1 more source

PCK for dummies

open access: yesEducación Química, 2013
AbstractThe propaganda related with the title of this editorial work says: “With more than 250 million books in print and more than 1,800 titles, For Dummies is the most widely recognized and highly regarded reference series in the world. Since 1991, For Dummies has helped millions make everything easier”.
openaire   +1 more source

Perceived importance and didactic difficulty of chemistry education: Insights from Czech teachers

open access: yesThe Curriculum Journal, EarlyView.
Abstract This empirical study examines how chemistry teachers in lower and upper secondary schools in the Czech Republic evaluate the content of the chemistry curriculum, focussing on its perceived importance and didactic difficulty. Based on a quantitative survey (N = 146), the study provides insight into the pedagogical content knowledge of ...
Jitka Lorenzová   +6 more
wiley   +1 more source

Using collaborative CoRe design in chemistry education to promote effective partnerships between associate and student teachers [PDF]

open access: yes, 2011
This article is a follow-up to my paper published in 2010 (Hume, 2010). In that paper I reported on the use of Content Representations (CoRes) in a chemistry education course to give student teachers insights into the professional knowledge of ...
Hume, Anne Christine
core  

Proteomic Profiling of Primary Hippocampal Neurons Reveals Noncanonical GFAP Expression and Metabolic Adaptations in Glia‐Free Culture

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Despite their widespread use as a research model, a comprehensive, quantitative proteomic profile of the cultured hippocampal neurons has remained unexplored. Here, we provide the first global proteomic characterization of primary murine hippocampal neurons cultured for 14 days under near‐physiological glucose conditions (2.5 mM).
Dominika Drulis‐Fajdasz   +6 more
wiley   +1 more source

Pedagogical Content Knowledge in Science Education

open access: yesEncyclopedia
The concept of Pedagogical Content Knowledge (PCK) was introduced by Shulman in 1986 as a distinctive form of teacher knowledge that transcends mere content expertise or general pedagogical skills.
Maria Chaitidou, Giorgos Peikos
doaj   +1 more source

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