Results 221 to 230 of about 3,602,392 (295)

Diagnostic Value of Microscopy, Galactomannan, and PCR in Aspergillus Culture-Positive BALF Samples: A Laboratory-Based Pilot Study. [PDF]

Mycoses
Govrins M, Vahedi-Shahandashti R, Lass-Flörl C.   +2 more
europepmc   +1 more source

Double‐Stranded DNA Reduces dsRNA Degradation in the Saliva and Significantly Enhanced RNAi‐Mediated Gene Silencing in Halyomorpha halys

Advanced Biology, EarlyView.
The invasive pest Halyomorpha halys causes significant crop losses requiring innovative pest control strategies such as RNA interference (RNAi). However, oral RNAi is largely ineffective in H. halys. This study shows that double‐stranded DNA (dsDNA) stabilizes dsRNA in saliva by inhibiting a highly expressed nuclease.
Venkata Partha Sarathi Amineni, Georg Petschenka, Aline Koch   +2 more
wiley   +1 more source

Rapid, season-specific PCR testing versus traditional diagnostics for pneumonia in the emergency department. [PDF]

BMC Pulm Med
Yu Y, Li Q.
europepmc   +1 more source

LIN28B Promotes Cancer Cell Dissemination and Angiogenesis

Advanced Biology, EarlyView.
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo, Sara Menegazzo, Marcella Pantile, Silvia Bresolin, Carlo Zanon, Alessandro Davini, Massimiliano Mazzone, Alessandra Biffi, Sanja Aveic   +8 more
wiley   +1 more source

Association of TILs and HER2-low status with pathological response in triple-negative breast cancer. [PDF]

Medicine (Baltimore)
Deliktaş Onur İ, Kurukafa D, Ağyol Y, Firat HG, Sertesen Çamöz E, Türkel A, Karabuğa B, Yenidünya S, Bayoğlu İV, Ateş Ö.   +9 more
europepmc   +1 more source

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

Advanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li, Sepehr Akhtarkhavari, Sumeng Qi, Jiawei Fan, Tu‐Yung Chang, Yao‐An Shen, JinMing Yang, Barbara S. Slusher, Ie‐Ming Shih, Stephanie Gaillard, Tian‐Li Wang   +10 more
wiley   +1 more source

Predictive value of shear wave elastography and molecular subtypes for postoperative efficacy in patients with early breast cancer. [PDF]

Ann Med
Zhao QY, Zhao B, Wu G.
europepmc   +1 more source

HMGB1 Derived from the Pyroptotic Microenvironment Promotes Macrophage Extracellular Traps in Hirschsprung‐Associated Enterocolitis

Advanced Biology, EarlyView.
HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang, Jing Li, Lili Song, Liya Pan, Chengchen Zhang, Zhiyan Zhan, Li Hong   +6 more
wiley   +1 more source

Universal amplification and sequencing of foot-and-mouth disease virus complete genomes using nanopore technology. [PDF]

BMC Genomics
Shaw AE, Lebani K, González Gordon L, Ihearahu UE, Wadsworth J, Hicks HM, Polo N, Freimanis G, Muhanguzi D, Tennakoon C, Orton RJ, Knowles NJ, Di Nardo A, Waters RA, Bronsvoort BM, King DP.   +15 more
europepmc   +1 more source