Results 221 to 230 of about 3,284,156 (346)

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

RNA fingerprinting by arbitrarily primed PCR. [PDF]

, 1994
Michael McClelland, John Welsh
openalex   +1 more source

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

FEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr, Michael Fauler, Thomas Zimmer, Bettina Jungwirth, Hubert Schrezenmeier, David Alexander Christian Messerer   +5 more
wiley   +1 more source

Implementation of a Multiplex PCR Amplification System Combined With Next-Generation Genome Sequencing to Decipher the Circulation of Human Coronavirus 229E Lineages in Southern France. [PDF]

J Med Virol
Hikmat H, Py J, Boschi C, Burel E, Le Targa L, Million M, Lesage L, Morand A, La Scola B, Colson P.   +9 more
europepmc   +1 more source

'Touchdown' PCR to circumvent spurious priming during gene amplification.

Nucleic Acids Research, 1991
R. H. Don, P. Cox, Brandon J Wainwright, K. Baker, J. Mattick   +4 more
semanticscholar   +1 more source

cDNA cloning of ovine interleukin 2 by PCR [PDF]

, 1990
Jane Goodall, David C. Emery, Anthony C.F. Perry, Leonard S. English, Len Hall   +4 more
openalex   +1 more source

An optimized protocol to detect high‐throughput DNA methylation from custom targeted sequences on 96 samples simultaneously

FEBS Open Bio, EarlyView.
Workflow of a high‐throughput technology for epigenotyping of differentially methylated CpGs in specific regions of the genome. The protocol works with small amounts of DNA extracted from blood or semen. The protocol consists of both enzymatic conversion of unmethylated cytosines and capture by hybridization with a custom panel.
Nathalie Iannuccelli, Sophie Valière, Julien Sarry, Cécile Donnadieu, Julie Demars   +4 more
wiley   +1 more source

Evaluation of the Antigen mariPOC Respi Test Versus PCR in Relation to Immunological Viral Response in Children With Lower Respiratory Tract Infection. [PDF]

Int J Microbiol
Eklundh A, Rhedin S, Peltola V, Waris M, Naucler P, Gaudenzi G, Iacobelli A, Lindh M, Andersson M, Mårtensson A, Alfvén T, Ryd-Rinder M.   +11 more
europepmc   +1 more source

Strategies for direct sequencing of PCR-amplified DNA. [PDF]

, 1994
Venigalla B. Rao
openalex   +1 more source

The cochaperone BAG3 promotes the stabilization of p53 under heat stress conditions

FEBS Open Bio, EarlyView.
Under heat stress, BAG3 translocates to the nucleus and forms a complex with Hsp70 and p53, thereby promoting p53 stabilization and enhancing its transcriptional activity. These findings suggest that BAG3 functions as a cochaperone that supports p53‐mediated stress responses in cooperation with Hsp70.
Ngoc Nguyen Thi Minh, Esther Lee, Soo‐A Kim   +2 more
wiley   +1 more source