Results 51 to 60 of about 3,764,452 (295)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Coronavirus disease-2019 (COVID-19) outbreak was first declared as emergency on January 30th2020 by World Health Organization (WHO). The Government of Pakistan presented a National action plan, which aimed to inhibit the spread of this Corona virus and ...
Ghazala Rubi, Irfan Malik, Zainab Javaid
doaj +1 more source
During survey, 12 Jackal jujube plant samples showing the symptoms of witches’ broom disease were collected from the Shivamogga district of Karnataka, India, between 2017 and 2018. The causal agent associated with Jackal jujube witches’ broom disease was
C. N. Lakshmınarayana Reddy +5 more
doaj +1 more source
Checking chess checks with chunks: A model of simple check detection [PDF]
The procedure by which humans identify checks in check positions is not well understood. We report here our experience in modelling this process with CHREST, a general-purpose cognitive model that has previously successfully captured a variety of ...
Gobet, F, Lane, PCR, Smith, RL
core
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
A distributed framework for semi-automatically developing architectures of brain and mind [PDF]
Developing comprehensive theories of low-level neuronal brain processes and high-level cognitive behaviours, as well as integrating them, is an ambitious challenge that requires new conceptual, computational, and empirical tools.
Gobet, F, Lane, PCR
core
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Simple environments fail as illustrations of intelligence: A review of R. Pfeifer and C. Scheier [PDF]
The field of cognitive science has always supported a variety of modes of research, often polarised into those seeking high-level explanations of intelligence and those seeking low-level, perhaps even neuro-physiological, explanations.
Gobet, F, Lane, PCR
core
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Introduction. Hepatitis B virus (HBV) infection in hemodialysis (HD) patients is a major concern, but limited information exists on the HBV genotyping in patients on maintenance HD in Turkey.Aim.
Murat Sayan, M.D., Cengiz Dogan
doaj +1 more source

