Results 61 to 70 of about 3,764,452 (295)

Learning perceptual schemas to avoid the utility problem [PDF]

open access: yes, 1999
This paper describes principles for representing and organising planning knowledge in a machine learning architecture. One of the difficulties with learning about tasks requiring planning is the utility problem: as more knowledge is acquired by the ...
Cheng, PCH, Gobet, F, Lane, PCR
core  

PCR Based Genotyping of Lulu Cattle of Nepal for A1, A2 Type Beta-caseins [PDF]

open access: yes, 2020
Lulu is an indigenous breed of cattle (Bos taurus) found in high altitude regions of western Nepal. Population of Lulu cattle has been declining due to introgression with other exotic breeds to increase milk productivity.
Budhathoki, N. (Nabina)   +7 more
core  

Improved detection of respiratory viruses in pediatric outpatients with acute respiratory illness by real-time PCR using nasopharyngeal flocked swabs [PDF]

open access: yes, 1999
Detection of respiratory viruses by realtime multiplexed PCR (M-PCR) and of RSV by M-PCR and immunofluorescence(IF) was evaluated using specimens collected by nasopharyngeal flocked swab(NFS) and nasal wash(NW).
Munywoki, Patrick   +5 more
core   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Combining low-level perception with expectations in CHREST [PDF]

open access: yes, 2003
The ability of humans to reliably perceive and recognise objects relies on an interaction between information seen in the visual image and prior expectations.
Gobet, F, Lane, PCR, Sykes, A
core   +1 more source

Microfluidic DNA amplification - a review [PDF]

open access: yes, 2009
The application of microfluidic devices for DNA amplification has recently been extensively studied. Here, we review the important development of microfluidic polymerase chain reaction (PCR) devices and discuss the underlying physical principles for the ...
Ozdemir, Pinar, Zhang, Yonghao
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

A rapid staining-assisted wood sampling method for PCR-based detection of pine wood nematode Bursaphelenchus xylophilus in Pinus massoniana wood tissue [PDF]

open access: yes, 2010
For reasons of unequal distribution of more than one nematode species in wood, and limited availability of wood samples required for the PCR-based method for detecting pinewood nematodes in wood tissue of Pinus massoniana, a rapid staining-assisted wood ...
Jia, W. H.   +5 more
core   +1 more source

Quantitative PCR and RT-PCR in virology. [PDF]

open access: yesGenome Research, 1993
In the last few years, molecular hybridization methods have been used extensively in basic and applied virology because of their technical flexibility and high specificity. Using these techniques, the detection of DNA and RNA viruses directly from clinical specimens, the analysis of the specific transcriptional activity of viral genes in vitro and in ...
CLEMENTI M   +5 more
openaire   +3 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

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