Results 21 to 30 of about 676,789 (144)
Zhongliu Fangzhi Yanjiu, 2020 Malignant melanoma is the most serious type of skin cancer with a high recurrence rate and death rate. Surgery still is the cornerstone of treatment for patients with stage Ⅱ and Ⅲ melanoma.
ZOU Hanhui, Li Tao
doaj +1 more source
Unexpected curative effect of PD-1 inhibitor in gastric cancer with brain metastasis: A case report
Frontiers in Oncology, 2023 BackgroundGastric cancer (GC) is the third most common cause of cancer-related death in the world. Several clinical trials have proven that the use of PD-1/PD-L1 inhibitors can improve the survival of late-stage GC patients and is suggested in NCCN and ...
Qijun Wang +32 more
doaj +1 more source
World Journal of Otorhinolaryngology-Head and Neck Surgery, 2022 Background PD‐1 and PD‐L1 inhibitors have emerged as promising treatments for patients with head and neck squamous cell carcinoma (HNSCC). Methods Systematic review and meta‐analysis of PD‐1 and PD‐L1 inhibitors in HNSCC.
Dylan A. Levy +9 more
doaj +1 more source
In vitro Interactions of Chicken Programmed Cell Death 1 (PD-1) and PD-1 Ligand-1 (PD-L1)
Frontiers in Cellular and Infection Microbiology, 2019 In the present study, we determined the in vitro characteristics and binding interactions of chicken PD-1 (chPD-1) and PD-L1 (chPD-L1) and developed a panel of specific monoclonal antibodies against the two proteins.
Vishwanatha R. A. P. Reddy +3 more
doaj +1 more source
Critical Care, 2016 Increasing evidence suggests that after the first pro-inflammatory hours, sepsis is characterized by the occurrence of severe immunosuppression. Several mechanisms have been reported to participate in sepsis-induced immune alterations affecting both innate and adaptive immunity.
Monneret, Guillaume +2 more
openaire +3 more sources
Anti-PD-1 antibody decreases tumour-infiltrating regulatory T cells
BMC Cancer, 2020 Background There are many types of therapies for cancer. In these days, immunotherapies, especially immune checkpoint inhibitors, are focused on. Though many types of immune checkpoint inhibitors are there, the difference of effect and its mechanism are ...
Kazushige Yoshida +15 more
doaj +1 more source
Machine and deep learning driven models for the design of heat exchangers with micro-finned tubes
Energy and AIThe design of micro-finned tube heat exchangers is a complex task due to intricate geometry, heat transfer goals, material selection, and manufacturing challenges. Nowadays, mathematical models provide valuable insights, aid in optimization, and allow us
Emad Efatinasab +3 more
doaj +1 more source
Antibodies, 2022 This study aimed to investigate PD-L1 and PD-1 expression in circulating CD20+ cells in diffuse larger B-cell lymphoma (DLBCL) and to evaluate the predictive and diagnostic performance of PD-L1 versus PD-1 expression in circulating CD20+ cells in DLBCL ...
Manal Mohamed Saber
doaj +1 more source
Immunotherapy protocols in lung cancer
Cancer Research, Statistics, and Treatment, 2018 Immunotherapy has emerged as a valuable treatment option in many advanced malignancies (especially lung cancer). The PD-1 inhibitors (nivolumab and pembrolizumab) and the PD-L1 inhibitors (durvalumab and atezolizumab) have been approved for use in ...
Nandini Menon, Sharada Mailankody
doaj +1 more source
PD-1 expression and clinical PD-1 blockade in B-cell lymphomas [PDF]
Blood, 2018 Programmed cell death protein 1 (PD-1) blockade targeting the PD-1 immune checkpoint has demonstrated unprecedented clinical efficacy in the treatment of advanced cancers including hematologic malignancies. This article reviews the landscape of PD-1/programmed death-ligand 1 (PD-L1) expression and current PD-1 blockade immunotherapy trials in B-cell ...
Xu-Monette, Zijun Y +2 more
openaire +2 more sources