A structural study of a C3H3 species coadsorbed with CO on Pd(1 1 1) [PDF]
, 2008 The combination of chemical-state-specific C 1s scanned-energy mode photoelectron diffraction (PhD) and O K-edge near-edge X-ray absorption fine structure (NEXAFS) has been used to determine the local adsorption geometry of the coadsorbed C3H3 and CO ...
Allegretti, F. +5 more
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Phase II Trial of IL-12 Plasmid Transfection and PD-1 Blockade in Immunologically Quiescent Melanoma. [PDF]
, 2020 PurposeTumors with low frequencies of checkpoint positive tumor-infiltrating lymphocytes (cpTIL) have a low likelihood of response to PD-1 blockade.
Algazi, Alain P +23 more
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International journal of health sciences, 2022 PD-1 or the programmed cell death protein 1 plays a major role in eliciting the immune checkpoint response of T cells. They are the inhibitory receptors induced in activated T cells. The application of these receptors earns a great interest to investigate, in-depth, their mechanism of action and therapeutic success. The US FDA has successfully approved
Muhammad Faraz Shamshad +6 more
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Can the plasma PD-1 levels predict the presence and efficiency of tumor-infiltrating lymphocytes in patients with metastatic melanoma? [PDF]
, 2019 Background: The immune response in melanoma patients is locally affected by presence of tumor-infiltrating lymphocytes (TILs), generally divided into brisk, nonbrisk, and absent.
Badalamenti G. +11 more
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Machine and deep learning driven models for the design of heat exchangers with micro-finned tubes
Energy and AIThe design of micro-finned tube heat exchangers is a complex task due to intricate geometry, heat transfer goals, material selection, and manufacturing challenges. Nowadays, mathematical models provide valuable insights, aid in optimization, and allow us
Emad Efatinasab +3 more
doaj +1 more source
Antibodies, 2022 This study aimed to investigate PD-L1 and PD-1 expression in circulating CD20+ cells in diffuse larger B-cell lymphoma (DLBCL) and to evaluate the predictive and diagnostic performance of PD-L1 versus PD-1 expression in circulating CD20+ cells in DLBCL ...
Manal Mohamed Saber
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Cell, 2015 Nivolumab and pembrolizumab are monoclonal antibodies that block the programmed death-1 receptor (PD-1, CD279), resulting in dis-inhibition of tumor-specific immune responses. Both are recently approved for use in the treatment of metastatic melanoma, and nivolumab as well for non-small cell lung cancer.
openaire +2 more sources
Combination Therapies of Guadecitabine and Immune Checkpoint Inhibitors in a Murine Triple-Negative Breast Cancer Model [PDF]
, 2020 Combination Therapies of Guadecitabine and Immune Checkpoint Inhibitors in a Murine Triple-Negative Breast Cancer Model Jamie-Jean Gilmer, Depts. of Biology and Chemistry, with Dr. Sarah Golding, Dept.
Gilmer, Jamie-Jean
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Antithymocyte Globulin Plus G-CSF Combination Therapy Leads to Sustained Immunomodulatory and Metabolic Effects in a Subset of Responders With Established Type 1 Diabetes. [PDF]
, 2016 Low-dose antithymocyte globulin (ATG) plus pegylated granulocyte colony-stimulating factor (G-CSF) preserves β-cell function for at least 12 months in type 1 diabetes.
Atkinson, Mark A +14 more
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Immunotherapy protocols in lung cancer
Cancer Research, Statistics, and Treatment, 2018 Immunotherapy has emerged as a valuable treatment option in many advanced malignancies (especially lung cancer). The PD-1 inhibitors (nivolumab and pembrolizumab) and the PD-L1 inhibitors (durvalumab and atezolizumab) have been approved for use in ...
Nandini Menon, Sharada Mailankody
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