Results 51 to 60 of about 676,789 (144)

Exploring the regulatory mechanism of intestinal flora based on PD-1 receptor/ligand targeted cancer immunotherapy

Frontiers in Immunology
Serving as a pivotal immunotherapeutic approach against tumors, anti-PD-1/PD-L1 therapy amplifies the immune cells’ capability to eliminate tumors by obstructing the interaction between PD-1 and PD-L1. Research indicates that immune checkpoint inhibitors
Xinran Gao, Xinran Gao, Xinran Gao, Jingting Jiang, Jingting Jiang, Jingting Jiang   +5 more
doaj   +1 more source

Anti-PD-1

Current Oncology Reports, 2022
Purpose of Review: Emerging data indicate that immune checkpoint blockade (ICB) in patients with metastatic melanoma can be stopped electively or at the time of toxicity with an acceptable risk for progression. However, the optimal treatment duration remains to be defined.
Jansen, Y, van der Veldt, A A M, Awada, G, Neyns, B   +3 more
openaire   +2 more sources

Triterpene Acid and Phenolics from Ancient Apples of Friuli Venezia Giulia as Nutraceutical Ingredients: LC-MS Study and In Vitro Activities

Molecules, 2019
Triterpene acid and phenolic constituents from nine ancient varieties of apple (Malus domestica) fruits cultivated in Fanna, Friuli Venezia Giulia region, northeast Italy, were analyzed and compared with four commercial apples (‘Golden Delicious ...
Stefania Sut, Gokhan Zengin, Filippo Maggi, Mario Malagoli, Stefano Dall’Acqua   +4 more
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Association of PD-1 and PD-L1 protein expression with selected clinical and morphological parameters in colorectal cancers

Polish Journal of Pathology
Colorectal cancer is the third most common cancer worldwide and the second cause of death from malignant tumors. Colorectal cancers are treated with surgery, chemotherapy, gene therapy and immunotherapy.
Paulina Poter, Sylwia Jankowska-Szabłowska, Tomasz Kolenda, Ewa Dobak, Elżbieta Urasińska, Katarzyna Karpińska-Łukaszewicz   +5 more
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Anti‐PD‐1/PD‐L1 Immunotherapy as a Potential Treatment Option for Lung Cancer: A Perspective Analysis of Opportunities and Challenges

Health Science Reports
Background and Aims Anti‐PD‐1/PD‐L1 immunotherapy has changed the treatment landscape of lung cancer. This new approach provides the ability to revitalize the immune system to specifically target and kill cancer cells, thereby creating a new treatment ...
Md Mohiuddin
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Efek Pemberian Kefir Susu Kambing Madu pada Gambaran Histopatologi Pankreas dan Fungsi Ginjal pada Tikus Diabetes

Amerta Nutrition
Latar Belakang: Diabetes menjadi penyakit yang semakin umum terjadi. Diabetes melitus tipe 2 merupakan penyakit metabolik kronis yang dapat menyebabkan kerusakan pankreas dan gangguan fungsi ginjal.
Amelia Luthfiyah Mulyadewi, Ibnu Malkan Bakhrul Ilmi, Angga Hardiansyah   +2 more
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STK25 Loss Augments Anti‐PD‐1 Therapy Efficacy by Regulating PD‐L1 Stability in Colorectal Cancer

Advanced Science
Tumor immune evasion is intricately linked to malignant tumor progression and contributes to the failure of anti‐cancer immunotherapy. Serine/threonine protein kinase 25 (STK25) has been previously implicated in the progression of various neoplastic ...
Xiaowen Qiao, Pu Xing, Hao Hao, Jiangbo Chen, Lin Song, Yifan Hou, Xinying Yang, Kai Weng, Jie Chen, Pin Gao, Tongkun Song, Hong Yang, Tianqi Liu, Yumeng Ran, Bo Chen, Wei Zhao, Jiabo Di, Zaozao Wang, Jun Zhang, Xiangqian Su, Beihai Jiang   +20 more
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Increased PD-1 expression in livers associated with PD-1-antibody-induced hepatotoxicity

BMC Immunology
Abstract Vanishing bile duct syndrome (VBDS) is a serious drug induced liver injury characterized by chronic cholestasis and loss of intrahepatic bile ducts. VBDS has been reported also following checkpoint inhibitor treatment. We compared CD3 + , CD4 + , CD8 + , CD20 + , CD57 + , PD-1 + and PD-L1 + lymphocyte infiltrates in liver biopsies of
Saarela, Miro, Parviainen, Essi, Lleo, Ana, di Tommaso, Luca, Raunio, Hanna, Kankaanranta, Krista, Vuopala, Katri, Rönkä, Aino, Nurmenniemi, Sini, Kallio, Raija, Jukkola, Arja, Selander, Katri S.   +11 more
openaire   +5 more sources

Meta-analysis of the correlation between glioma prognosis and PD-1/PD-L1 expression

Asian Journal of Surgery, 2023
Chang-cheng Ren, Bo Xu, Min-shu Wang, Feng He, Jun-hui Chen, Liang Liao, Wu Liang   +6 more
doaj   +1 more source

Anti PD-1 protitelesa

Onkologija, 2017
Protein programirane celične smrti 1:PD-1 (Programmed cell death protein 1) je transmembranski protein, ki je izražen na celicah T, B, NK ter monocitih in dendritičnih celicah.
Janja Ocvirk
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