Results 201 to 210 of about 85,787 (336)

Small Hepatoid Variant of Solid Pseudopapillary Neoplasm of the Pancreas: A Unique Case With Long‐term Follow‐up

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Hepatoid tumors are rare neoplasms that arise outside the liver but exhibit morphological and immunophenotypic features resembling hepatocellular carcinoma. Although hepatoid differentiation sometimes occurs in pancreatic ductal adenocarcinoma, its occurrence in solid pseudopapillary neoplasm (SPN) is exceedingly rare.
Hisakazu Matsumoto, Kosuke Minaga, Shotaro Ueno, Asuka Sone, Eiki Chikugo, Kohei Tonomura, Shogo Nakano, Yoshito Uenoyama, Kazuo Ono, Yukitaka Yamashita   +9 more
wiley   +1 more source

Malassezia und PDAC

Basidiomycete yeasts of the genus Malassezia occur as commensals on the skin and mucous membranes of humans and warm-blooded animals. Some of the associated species are associated with the occurrence of certain skin diseases and systemic infections. The genus comprises 18 species and has an unusual, lipid-rich envelope.
openaire   +1 more source

Impaired Adipose Anabolism in Pancreatic Cancer Cachexia Is Reversed by HuR Inhibition

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 2, April 2026.
ABSTRACT Background Cachexia is defined by chronic loss of fat and muscle, is a frequent complication of pancreatic ductal adenocarcinoma (PDAC) and negatively impacts patient outcomes. Nutritional supplementation cannot fully reverse tissue wasting, and the mechanisms underlying this phenotype are unclear.
Paige C. Arneson‐Wissink, Katherine Pelz, Beth Worley, Heike Mendez, Peter Pham, Parham Diba, Peter R. Levasseur, Grace McCarthy, Alex Chitsazan, Jonathan R. Brody, Aaron J. Grossberg   +10 more
wiley   +1 more source

Paired Duodenal and Salivary Microbiome Analysis in Pancreatic Cancer Without Duct Obstruction. [PDF]

United European Gastroenterol J
Archibugi L, Bertoldi L, Benvenuto G, Sattin E, Ponz De Leon Pisani R, Fortunato C, Mariani A, Rossi G, Petrone MC, Valle G, Reni M, Falconi M, Arcidiacono PG, Capurso G.   +13 more
europepmc   +1 more source

CD11b agonism overcomes PDAC immunotherapy resistance [PDF]

Nature Reviews Gastroenterology & Hepatology, 2019
openaire   +2 more sources

NDUFS1‐Mediated Mitochondrial Complex I Activity Maintains Pancreatic Cancer Stemness by Promoting PAX2 Hypomethylation

MedComm, Volume 7, Issue 4, April 2026.
Pancreatic cancer stem cells (CSCs) maintain stemness and tumorigenicity through NDUFS1‐mediated complex I activity, which is transcriptionally upregulated via the CD147‐STAT3 signaling axis. Enhanced oxidative phosphorylation (OXPHOS) and NAD+ production driven by this CD147‐NDUFS1 axis subsequently trigger the SIRT1‐DNMT1 metaboloepigenetic signaling
Xin‐Yu Fan, Wen Li, Ying Shi, Bao‐Qing Xu, Hao Wang, Ruo‐Fei Tian, Zi‐Chuan Duan, Jing Fan, Jia‐Rong Liu, Xiu‐Xuan Sun, Bin Wang, Li‐Juan Wang, Ke Wang, Shi‐Jie Wang, Xiang‐Min Yang, Hong‐Yong Cui, Zhi‐Nan Chen, Ling Li   +17 more
wiley   +1 more source

Navigating the complexities of ferroptosis in pancreatic ductal adenocarcinoma: roles, mechanisms and potential applications. [PDF]

Cell Death Discov
Xiao Y, Wang W, Wang G, Liu Y, Gong J.
europepmc   +1 more source

NR3C1, LAX1, and RCAN3 as Circulating Epigenetic Biomarkers for Prognosis and Chemotherapy Response Prediction in Metastatic Pancreatic Cancer

MedComm, Volume 7, Issue 4, April 2026.
Clinical utility of liquid biopsy‐based epigenetic profiling in PDAC management. Aberrant methylation of LAX1, RCAN3, and NR3C1 was identified in cfDNA from mPDAC patients, highlighting their potential as non‐invasive epigenetic biomarkers. Methylation levels of these genes showed prognostic value, supporting their relevance for patient stratification ...
Pablo Cano‐Ramírez, Marta Toledano‐Fonseca, María Teresa Cano‐Osuna, Nerea Herrera‐Casanova, Emilio Carrillo‐Pecero, Antonio Rodríguez‐Ariza, Enrique Aranda, María Victoria García‐Ortiz   +7 more
wiley   +1 more source

KRAS-elicited PDIA6 blocks PERK-dependent immunogenic cell death in pancreatic carcinoma. [PDF]

Oncoimmunology
Zhao L, Liu P, Kroemer G, Kepp O.
europepmc   +1 more source

Enhancing Oncolytic Adenovirus Replication by Early Region 1A Protein‐Mediated Degradation of E1A Binding Protein p300

MedComm, Volume 7, Issue 4, April 2026.
E1A is an important protein for adenovirus to initiate viral replication. Previous reports have shown that E1A binds to p300 as a regulatory factor. However, our study provides a new perspective that E1A promotes oncolytic adenovirus replication by degrading p300.
Boduan Xiao, Qingzhe Yang, Shichuan Hu, Jianchuan Hu, Zhongbing Qi, Yao Zhang, Yu Qin, Ping Cheng   +7 more
wiley   +1 more source