Results 211 to 220 of about 54,977 (304)

Ferroptosis-Based Nanotherapy for Pancreatic Ductal Adenocarcinoma Through Glutathione Depletion and Iron Accumulation. [PDF]

Int J Nanomedicine
Yoon S, Son J, Choi Y, Kim J, Jang J, Lee HY, Choi J.   +6 more
europepmc   +1 more source

Spatial and Temporal Heterogeneity of Macrophage Efferocytosis in Tumors: Emerging Implications for Immunotherapy Biomarkers and Therapeutic Timing

Cancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Resistance to immune checkpoint blockade (ICB) remains a major barrier in cancer therapy, reflecting the fact that tumor immunity is governed not only by cell type abundance but also by spatial organization and temporal dynamics within the tumor microenvironment (TME).
Shanyi Li, Jilei Li, Zhenyu Zhang, Sizhe Wang, Chunzheng Ma   +4 more
wiley   +1 more source

Biglycan Secreted by Tumor Stromal Cells Is a Predictive Marker for the Early Recurrence of Pancreatic Cancer. [PDF]

Pathol Int
Tanaka H, Maishi N, Matsuda A, Morimoto H, Fujii M, Tsumita T, Mitsuhashi T, Matsuno Y, Hida Y, Nakamura T, Hirano S, Hida K.   +11 more
europepmc   +1 more source

Organoids in Precision Radiotherapy: Methodological Foundations, Tumor‐Specific Evidence, and Translational Roadmaps

Cancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Background Radiotherapy remains a cornerstone of cancer treatment, while its efficacy is often limited by tumor radioresistance and the risk of normal tissue toxicity. Conventional preclinical models, including two‐dimensional (2D) cell cultures and murine xenografts, exhibit significant limitations in recapitulating human tumor ...
Yixian Zhu, Yawei Jiao, Jiao Xue, Xiaoli Lv, Songbing Qin   +4 more
wiley   +1 more source

The Acidic Exosomal miR-1246/WASF3 Axis Regulates Hepatic Stellate Cell Activation and Stiff ECM Remodeling to Promote Pancreatic Ductal Adenocarcinoma Liver Metastasis. [PDF]

Int J Biol Sci
Li D, Chu X, Zhang F, Ma Y, Liu W, Li P, Fang X, Wang C, Tian X, Yang Y, Yang Y.   +10 more
europepmc   +1 more source

A Review of Senescence‐Associated Secretory Phenotype‐Mediated Remodeling of the Tumor Microenvironment: Implications for Cancer Progression and Therapy

Cancer Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background Cellular senescence influences cancer progression through irreversible cell‐cycle arrest, immune surveillance, and paracrine signaling mediated by the senescence‐associated secretory phenotype (SASP). SASP comprises inflammatory cytokines, chemokines, growth factors, and matrix‐remodeling enzymes that regulate the tumor ...
Sneha Pallatt, Sibin Nambidi, Antara Banerjee, Surajit Pathak   +3 more
wiley   +1 more source

Reliance on topographical coding alone may overestimate survival in pancreatic ductal adenocarcinoma. [PDF]

Surg Pract Sci
Falk W, Andersson R, Ansari D.
europepmc   +1 more source

Preoperative immunonutrition as a strategy for reducing oxidative stress and inflammation in pancreatic ductal adenocarcinoma. [PDF]

Front Immunol
Kostro P, Wolszczak-Biedrzycka B, Kostro E, Matowicka-Karna J, Kamocki Z, Pawlukianiec C, Maciejczyk M, Zalewska A, Dorf J.   +8 more
europepmc   +1 more source

The tumor microenvironment in pancreatic cancer: from composition to therapeutic targeting. [PDF]

Biochem Soc Trans
Gomes BM, Xavier PLP.
europepmc   +1 more source

Cancer‐related pain: A bidirectional modulator of cancer progression

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
CRP and tumour progression engage in a dynamic, bidirectional circuit mediated by multiple mechanisms involving neuroimmunology and cancer ‐neuroscience. Analgesic interventions may affect tumour progression, while anticancer therapies can influence pain. Targeting pain in cancer may have promising therapeutic value in cancer progression.
Junzhe He, Yu Zhang, Qian Liu, Biao Yan, Peiwei Chai, Renbing Jia   +5 more
wiley   +1 more source