Early cellular plasticity promotes progression and dissemination in pancreatic adenocarcinoma. [PDF]
Innamorati G +4 more
europepmc +1 more source
ABSTRACT Purpose To investigate contrast‐enhanced T1‐weighted MRI and diffusion‐weighted magnetic resonance imaging (DWI) for early prediction of tumor response to combined irreversible electroporation (IRE) and anti‐PD‐1 immunotherapy. Methods Murine pancreatic ductal adenocarcinoma (PDAC) cells KRAS* were inoculated into the pancreas of C57BL/6 mice.
Qizhen Cao +9 more
wiley +1 more source
Detection of plasma EV-associated TRAIL by nanoscale flow cytometry for liver metastasis prediction in PDAC. [PDF]
Huang CX +6 more
europepmc +1 more source
Treating Pancreatic Ductal Adenocarcinoma: The Targeted Revolution is Here. [PDF]
May MS, Park W, O'Reilly EM.
europepmc +1 more source
ABSTRACT Background A randomized phase II screening trial of gemcitabine, nab‐paclitaxel, and cisplatin with a medically supervised ketogenic diet (MSKD) versus usual diet (non‐MSKD) was conducted in patients with treatment‐naive metastatic pancreatic ductal adenocarcinoma (PDAC).
Gayle S. Jameson +21 more
wiley +1 more source
A STING signaling relay from tumor cells to macrophages mediates the improved efficacy of combination chemotherapy in pancreatic cancer. [PDF]
Ding H +14 more
europepmc +1 more source
Dynamic Covalent Polymeric Foams: En Route to a Sustainable Lightness
Dynamic covalent polymer foams (DCPFs) combine lightweight cellular structures with adaptive polymer networks, enabling self‐healing, reprocessability, and recyclability. By integrating reversible covalent bonds into foam architectures, these materials open new pathways toward sustainable porous polymers within a circular materials economy.
Antoine Adjaoud +3 more
wiley +1 more source
Effective allogeneic natural killer cell therapy for pancreatic adenocarcinoma avails conserved activating receptors and evades HLA I-driven inhibition. [PDF]
Lee SN +3 more
europepmc +1 more source
Spatial heterogeneity of antibody–drug conjugate targets in pancreatic ductal adenocarcinoma
Abstract Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease, with limited therapeutic options, few patients showing targetable molecular changes. New therapeutic strategies are necessary. Antibody–drug conjugates (ADCs) have emerged as alternative therapeutic strategies across various cancer types. Herein, we analyze the expression and spatial
Deema Sabtan +10 more
wiley +1 more source
Toward Timely Diagnosis of Pancreatic Cancer: Revolutionizing Early Detection Through Genomics, Artificial Intelligence, and Noninvasive Biomarkers. [PDF]
Hussain MM +5 more
europepmc +1 more source

