Results 111 to 120 of about 2,405 (181)

A novel neutralizing antibody recognizing a conserved conformational epitope in PDCoV S1 protein and its therapeutic efficacy in piglets

Journal of Virology
Porcine deltacoronavirus (PDCoV) is an enteric pathogen that burdens the global pig industry and is a public health concern. The development of effective antiviral therapies is necessary for the prevention and control of PDCoV, yet to date, there are few
Rui Chen, Guiping Zhou, Junpeng Yang, Rong Yuan, Ying Sun, Yixiao Liang, Rui Wu, Yiping Wen, Yiping Wang, Qin Zhao, Senyan Du, Qigui Yan, Sanjie Cao, Xiaobo Huang   +13 more
doaj   +1 more source

Transcriptomic Analysis of PDCoV-Infected HIEC-6 Cells and Enrichment Pathways PI3K-Akt and P38 MAPK

Porcine Deltacoronavirus (PDCoV) is a newly identified coronavirus that causes severe intestinal lesions in piglets. However, the understanding of how PDCoV interacts with human hosts is limited.
Jing Chen, Hao, Jiayi, Yuhang Jiang, Maopeng Wang, Jiang, Yuhang, Pengfei Hao, Zihan Gao, Guoqing Zhang, Letian Li, Chang Li, Jin, Ningyi, Ningyi Jin, Wang, Maopeng, Jiayi Hao, Hao, Pengfei, Li, Letian, Gao, Zihan, Zhang, Guoqing, Li, Chang, Chen, Jing   +19 more
core   +1 more source

A novel double-antibody sandwich ELISA based on monoclonal antibodies against the viral spike protein detects porcine deltacoronavirus infection

Microbiology Spectrum
Porcine deltacoronavirus (PDCoV) is a significant emerging pathogen that causes severe enteric disease in swine, and therefore significant economic losses in the pig farming industry.
Yingjie Bai, Ruiming Yu, Guangqing Zhou, Liping Zhang, TianTian Wang, Ya Liu, Dongsheng Wang, Zhongwang Zhang, Yonglu Wang, Huichen Guo, Li Pan, Xinsheng Liu   +11 more
doaj   +1 more source

Deltacoronavirus HKU11, HKU13, PDCoV (HKU15) and HKU17 spike pseudoviruses enter avian DF-1 cells via clathrin-mediated endocytosis in a Rab5-, Rab7- and pH-dependent manner

Porcine deltacoronavirus (PDCoV), also known as HKU15, is a swine enteropathogenic virus that is believed to have originated in birds. PDCoV belongs to the genus Deltacoronavirus (DCoV), the members of which have mostly been identified in diverse avian ...
Bin Wang, Yu Huang, Wei Chen, Qi-Zhang Liang, Chun-Miao Ji, Yao-Wei Huang, Feng Cong   +6 more
core   +1 more source

Establishment and Application of Triple-qPCR for HEV, PEDV and PDCoV in Pork and Its Products

Shipin gongye ke-ji
Animal-derived food safety incidents caused by zoonotic diseases occur frequently. In order to control and ensure the safety of pork consumption from its raw material source and to control the cost of pork and its products consumption, this study constructed a triple real-time fluorescent quantitative PCR (qPCR) method that can simultaneously detect ...
Xinghong YU, Jing ZHANG, Wei AN, Miao YANG, Li XIE, Jiaxin SHU, Changhua XUE, Qiao ZHENG, Hua LIN, Guoquan HAN   +9 more
openaire   +1 more source

Molecular Basis of Plasticity of Porcine Delta Coronavirus (PDCoV) & Development of Countermeasures Against Infection [PDF]

Thesis (Ph.D.)--University of Washington, 2024Porcine deltacoronavirus (PDCoV) is an enteric pathogen that infects a broad range of mammal and avian species.
Rexhepaj, Megi
core  

Porcine Deltacoronavirus (PDCoV): From Emerging Swine Enteric Coronavirus to a Potential Coronavirus to Infect Humans. [PDF]

Viruses
Chen X, Zhang Z, Cheng H, Qi S, Wang P.
europepmc   +1 more source

Integrated multi-omics analysis identifies PPAR signaling network associations with metabolic-immune dysregulation and intestinal injury in PDCoV-infected piglets. [PDF]

Virulence
Guo X, A C, Ding Y, Zhang Y, Zhang H, Wang J, Zhang Y, Wang T.   +7 more
europepmc   +1 more source

Low-pH-induced conformational changes in the spike protein promote porcine deltacoronavirus infection by enhancing viral binding efficiency to the porcine aminopeptidase receptor. [PDF]

J Virol
Yu R, Zhang L, Zhou P, Zhang Z, Bai Y, Wang D, Liu Y, Wang X, Du G, Yuan L, Guo H, Pan L, Liu X.   +12 more
europepmc   +1 more source

Porcine deltacoronavirus nucleocapsid protein inhibits RIG-I signaling pathway by suppressing G3BP1-mediated stress granules formation. [PDF]

Virulence
Guo M, Hu Y, Wang D, Tang Y, Yuan J, Shi C, Zu S, Wei Z.   +7 more
europepmc   +1 more source