Results 81 to 90 of about 2,405 (181)

Development of a High‐Resolution Melting (HRM)‐Based Multiplex Real‐Time PCR Assay of PEDV, TGEV, PoRV, PDCoV, PRV, and PRRSV

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Six key viral pathogens—porcine epidemic diarrhea virus (PEDV), transmissible gastroenteritis virus (TGEV), porcine rotavirus (PoRV), porcine deltacoronavirus (PDCoV), pseudorabies virus (PRV), and porcine reproductive and respiratory syndrome virus (PRRSV)—inflict substantial economic losses on the global swine industry.
Fangshan Wang, Jing Ren, Yawen Wang, Chen Yuan, Tairan Sun, Jinhai Huang, Qinye Song, Nan-hua Chen   +7 more
wiley   +1 more source

PEDV and PDCoV Pathogenesis: The Interplay Between Host Innate Immune Responses and Porcine Enteric Coronaviruses [PDF]

Frontiers in Veterinary Science, 2019
El virus enteropatógeno de la diarrea epidémica porcina (PEDV) y el deltacoronavirus porcino (PDCoV), miembros de la familia de los coronavirus, representan la mayoría de la diarrea acuosa letal en cerdos neonatos en la última década. Estos dos virus plantean importantes cargas económicas y de salud pública, incluso cuando ambos continúan surgiendo y ...
Surapong Koonpaew, Samaporn Teeravechyan, Phanramphoei Namprachan Frantz, Thanathom Chailangkarn, Anan Jongkaewwattana   +4 more
openaire   +3 more sources

Porcine Deltacoronavirus Nsp13 Suppresses the Assembly of the MAVS‐TBK1‐IRF3 Complex and IRF9 Nuclear Translocation

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Porcine deltacoronavirus (PDCoV) is an emerging enteric coronavirus that causes substantial morbidity in swine and may pose a zoonotic risk because of its cross‐species transmission potential. Type I interferon (IFN‐I) signaling is central to antiviral defense, initiated through the mitochondrial antiviral signaling (MAVS)–TBK1–IFN regulatory factor 3 (
Ying Wang, Shijin Lan, Zhenghui Fang, Shixing Yang, Xiaochun Wang, Quan Shen, Yuwei Liu, Ping Wu, Chenglin Zhou, Wen Zhang, Likai Ji, Jianchao Wei   +11 more
wiley   +1 more source

A comprehensive PDCoV-host proteome interaction map reveals potential antiviral targets

PLOS Pathogens
Porcine deltacoronavirus (PDCoV), an enteric member of the coronavirus family, has emerged globally over the past decade, causing significant impacts on the swine industry. While studies of virus-host protein interactions provide crucial insights into viral engagement with host cells during infection, research specifically targeting PDCoV-host ...
Wenjun Yan, Kailu Wang, Song Liu, Rongbin Qiu, Qingcheng Yang, Hao Li, Siyu Huang, Chengyao Hou, Qinyuan Chu, Yue Sun, Yizhi Tang, Changwei Lei, Yiming Tian, Hongning Wang, Xin Yang   +14 more
openaire   +2 more sources

Susceptibility of porcine IPEC-J2 intestinal epithelial cells to infection with porcine deltacoronavirus (PDCoV) and serum cytokine responses of gnotobiotic pigs to acute infection with IPEC-J2 cell culture-passaged PDCoV

Veterinary Microbiology, 2018
The porcine small intestinal epithelial cell line, IPEC-J2, is useful to characterize the interactions of enterocytes with enteric viruses in vitro. We investigated whether IPEC-J2 cells are susceptible to porcine deltacoronavirus (PDCoV) infection. We conducted quantification of infectious virus or viral RNA, immunofluorescent (IF) staining for the ...
Kwonil Jung, Ayako Miyazaki, Hui Hu, Linda J. Saif   +3 more
openaire   +2 more sources

Emergence of a Highly Virulent Porcine Epidemic Diarrhea Virus (PEDV) G2c Subtype in China: Isolation, Genetic and Pathogenic Characterization, and Cross‐Neutralizing Antibody Response

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Porcine epidemic diarrhea virus (PEDV), an enteropathogenic coronavirus causing high mortality in neonatal piglets, continues to threaten global swine industries. Frequent mutations in the spike (S) protein of PEDV, particularly in emerging variants, have substantially compromised commercial vaccine efficacy.
Yang-Yang Li, Chuan-Hao Fan, Hai-Xia Li, Hui-Qiang Zhen, Ye-Qing Zhu, Shouyu Wang, Bin Wang, Yao-Wei Huang, Linzhu Ren   +8 more
wiley   +1 more source

Ten Years Later: Molecular Detection and Circulation of Enteric Viruses in Italian Pig Herds

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Enteric viral infections remain a major challenge for the swine industry, particularly in young animals, and represent a potential source of zoonotic risk. Ten years after a previous survey conducted in Italy, we performed a cross‐sectional study investigating mostly the same viruses to evaluate the persistence and circulation of different enteric ...
Ilaria Di Bartolo, Fabio Ostanello, Giovanni Ianiro, Luca De Sabato, Chiara Settanni, Irene Berselli, David Ranucci, Marina Monini, Fedor Korennoy   +8 more
wiley   +1 more source

A gut microbiota‐bile acid axis inhibits the infection of an emerging coronavirus by targeting its cellular receptor aminopeptidase N

iMeta
Porcine deltacoronavirus (PDCoV) is a significant pathogen of swine with a global distribution, leading to severe gastrointestinal disease and substantial economic losses.
Ya‐Qing Zhang, Bin Wang, Yong‐Le Yang, Jin‐Xin Meng, Meng‐Di Zhang, Yi‐Ke Li, Bo Dong, Yanan Zhang, Bo‐Wen Liu, Dong Yang, Chun‐Miao Ji, Yao‐Wei Huang, Shu Jeffrey Zhu   +12 more
doaj   +1 more source

Natural Products as Potential Resource Library for Control of Major Swine Enteric Viruses

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Major swine enteric viruses (SEVs), including porcine epidemic diarrhea virus (PEDV), porcine deltacoronavirus (PDCoV), transmissible gastroenteritis virus (TGEV), swine acute diarrhea syndrome coronavirus (SADS‐CoV), and porcine rotavirus (PoRV), cause severe gastrointestinal diseases in pigs, leading to huge economic losses to the swine industry ...
Jialu Zhang, Yuqian Liu, Shuying Ren, Zhouyuan Wang, Yunxia Li, Lianci Peng, Rendong Fang, Jianchao Wei   +7 more
wiley   +1 more source

Genetic manipulation of porcine deltacoronavirus reveals insights into NS6 and NS7 functions: a novel strategy for vaccine design

Emerging Microbes and Infections, 2020
Porcine deltacoronavirus (PDCoV) is an emerging swine coronavirus that causes severe diarrhea, resulting in high mortality in neonatal piglets. Despite widespread outbreaks in many countries, no effective PDCoV vaccines are currently available.
Mengjia Zhang, Wan Li, Peng Zhou, Dejian Liu, Rui Luo, Anan Jongkaewwattana, Qigai He   +6 more
doaj   +1 more source