Results 61 to 70 of about 2,664 (192)

Emergence of a Highly Virulent Porcine Epidemic Diarrhea Virus (PEDV) G2c Subtype in China: Isolation, Genetic and Pathogenic Characterization, and Cross‐Neutralizing Antibody Response

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Porcine epidemic diarrhea virus (PEDV), an enteropathogenic coronavirus causing high mortality in neonatal piglets, continues to threaten global swine industries. Frequent mutations in the spike (S) protein of PEDV, particularly in emerging variants, have substantially compromised commercial vaccine efficacy.
Yang-Yang Li   +8 more
wiley   +1 more source

Development and application of an ELISA for the detection of porcine deltacoronavirus IgG antibodies. [PDF]

open access: yesPLoS ONE, 2015
Porcine deltacoronavirus (PDCoV), also known as porcine coronavirus HKU15, was first detected in North America in early 2014 and associated with enteric disease in pigs, resulting in an urgent need to further investigate the ecology of this virus.
Anil Thachil   +4 more
doaj   +1 more source

Nanoparticle vaccines based on the receptor binding domain of porcine deltacoronavirus elicit robust protective immune responses in mice

open access: yesFrontiers in Immunology
BackgroundPorcine deltacoronavirus (PDCoV), a novel swine enteropathogenic coronavirus, challenges the global swine industry. Currently, there are no approaches preventing swine from PDCoV infection.MethodsA new PDCoV strain named JS2211 was isolated ...
Yuanhong Wang   +13 more
doaj   +1 more source

Susceptibility of porcine IPEC-J2 intestinal epithelial cells to infection with porcine deltacoronavirus (PDCoV) and serum cytokine responses of gnotobiotic pigs to acute infection with IPEC-J2 cell culture-passaged PDCoV

open access: yesVeterinary Microbiology, 2018
The porcine small intestinal epithelial cell line, IPEC-J2, is useful to characterize the interactions of enterocytes with enteric viruses in vitro. We investigated whether IPEC-J2 cells are susceptible to porcine deltacoronavirus (PDCoV) infection. We conducted quantification of infectious virus or viral RNA, immunofluorescent (IF) staining for the ...
Kwonil Jung   +3 more
openaire   +2 more sources

Recent Advances in Lateral Flow Immunoassay for Rapid Diagnosis of Viral Diseases

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Viral diseases are a major threat to human and animal health, as illustrated by recent pandemics like COVID‐19 and African swine fever (ASF). Timely, accurate detection of viral infections is critical for effective disease control. Among diverse diagnostic techniques, lateral flow immunoassay (LFIA) has become a widely used on‐site testing tool, owing ...
Quanyu Ren   +8 more
wiley   +1 more source

A Novel Adjuvant System for High‐Efficiency Subunit Vaccines Against Porcine Deltacoronavirus

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Summary The immunopotentiation efficacy of polydimethyl diallyl ammonium chloride (pDMDAAC) nanoparticles (NPs) as an adjuvant for the spike (S) protein subunit vaccine of porcine deltacoronavirus (PDCoV) was investigated, with particular emphasis on the combination of the NPs with the STING agonist cGAMP.
Shuangyuan Xu   +9 more
wiley   +1 more source

Iowa Animal Industry News, 2015, Vol. 16, no. 1 [PDF]

open access: yes, 2015
Newsletter produced by Department of Agriculture and Land Stewardship about the animal industry in Iowa.

core  

Porcine Deltacoronavirus Nucleocapsid Protein Suppressed IFN-β Production by Interfering Porcine RIG-I dsRNA-Binding and K63-Linked Polyubiquitination

open access: yesFrontiers in Immunology, 2019
Porcine deltacoronavirus (PDCoV) is a newly detected porcine coronavirus causing serious vomiting and diarrhea in piglets, especially newborn piglets. There has been an outbreak of PDCoV in worldwide since 2014, causing significant economic losses in the
Ji Likai   +6 more
doaj   +1 more source

A Candidate Antigen of the Recombinant Membrane Protein Derived from the Porcine Deltacoronavirus Synthetic Gene to Detect Seropositive Pigs

open access: yesViruses, 2023
Porcine deltacoronavirus (PDCoV) is an emergent swine coronavirus which infects cells from the small intestine and induces watery diarrhea, vomiting and dehydration, causing mortality in piglets (>40%).
Francisco Jesus Castañeda-Montes   +4 more
doaj   +1 more source

Prediction and Verification of Curcumin as a Potential Drug for Inhibition of PDCoV Replication in LLC-PK1 Cells

open access: yesInternational Journal of Molecular Sciences, 2023
Porcine deltacoronavirus (PDCoV) is an emerging swine enteropathogenic coronavirus (CoV) that causes lethal watery diarrhea in neonatal pigs and poses economic and public health burdens. Currently, there are no effective antiviral agents against PDCoV.
Xuefei Wang   +6 more
openaire   +2 more sources

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