Results 51 to 60 of about 2,405 (181)
Substrate specificity of PDCoV nsp5-mediated cleavage.
, 2023 Cleavage sequences of viral and host substrates by PDCoV nsp5 were collected and analyzed. The glutamine (Q) in the P1 position was conserved among the different substrates. (TIF)
Jianfei Chen (3186999) +9 more
core +1 more source
Viruses, 2021 Porcine deltacoronavirus (PDCoV), an emerging enteropathogenic coronavirus, causes diarrhoea in suckling piglets and has the potential for cross-species transmission. No effective PDCoV vaccines or antiviral drugs are currently available.
Puxian Fang +9 more
doaj +1 more source
Complementation expression of POLDIP3 disrupts PDCoV replication in POLDIP3-/- cells.
, 2023 (A) POLDIP3 complementation inhibits PDCoV replication in POLDIP3-/- cells by IFA. POLDIP3-/- cells were transduced with POLDIP3 or the vector control described above and then infected with PDCoV at an MOI of 1 for 24 h. Meanwhile, another WT and POLDIP3-
Jianfei Chen (3186999) +9 more
core +1 more source
Viruses, 2022 Porcine deltacoronavirus (PDCoV) is a recently discovered enteropathogenic coronavirus and has caused significant economic impacts on the pork industry. Although studies have partly uncovered the molecular mechanism of PDCoV–host interaction, it requires
Yang Wu +9 more
doaj +1 more source
Virulence, 2021 Porcine deltacoronavirus (PDCoV) is a potentially emerging zoonotic pathogen that causes severe diarrhea in young pigs, with a risk of fatal dehydration.
Xinrong Zhou +7 more
doaj +1 more source
Emerging Microbes and Infections, 2020 Porcine deltacoronavirus (PDCoV) is a newly emerging threat to the global porcine industry. PDCoV has been successfully isolated using various medium additives including trypsin, and although we know it is important for viral replication, the mechanism ...
Yue-Lin Yang +5 more
doaj +1 more source
Viruses, 2021 Porcine deltacoronavirus (PDCoV) is an emerging infectious disease of swine with zoonotic potential. Phylogenetic analysis suggests that PDCoV originated recently from a host-switching event between birds and mammals.
Diana Cruz-Pulido +5 more
doaj +1 more source
Swine GBP1 restricts PDCoV replication via disrupting the replication and transcription complex formation. [PDF]
J VirolABSTRACT Porcine deltacoronavirus (PDCoV) has been prevalent worldwide for over a decade, causing considerable economic damage to the pig industry and posing a potential threat to public biosecurity.
Zhang K +12 more
europepmc +4 more sources
Porcine deltacoronavirus resists antibody neutralization through cell-to-cell transmission
Emerging Microbes and Infections, 2023 Porcine deltacoronavirus (PDCoV) is an emerging enteric coronavirus that has been reported to infect a variety of animals and even humans. Cell–cell fusion has been identified as an alternative pathway for the cell-to-cell transmission of certain viruses,
Sijin Xia +8 more
doaj +1 more source
Infection of higher passage of PDCoV induced POLDIP3 reduction.
, 2023 IPEC-J2 cells were mock-infected or infected with PDCoV with higher passage (passage 120) at an MOI of 1 and then lysed for detection of endogenous POLDIP3 at indicated timepoints by Western blotting analysis. (TIF)
Jianfei Chen (3186999) +9 more
core +1 more source