Results 41 to 50 of about 2,405 (181)

Evolutionary plasticity of zoonotic porcine Deltacoronavirus (PDCoV): genetic characteristics and geographic distribution

open access: yesBMC Veterinary Research, 2022
AbstractThe emergence and rapid spread of the acute respiratory syndrome coronavirus-2 have confirmed that animal coronaviruses represent a potential zoonotic source. Porcine deltacoronavirus is a worldwide evolving enteropathogen of swine, detected first in Hong Kong, China, before its global identification.
Amina Nawal Bahoussi   +5 more
openaire   +3 more sources

Overexpression of POLDIP3 inhibits PDCoV replication in IPEC-J2 cells.

open access: yes, 2023
(A) IPEC-J2 cells were transduced with a bicistronic lentivirus vector expressing ZsGreen alone (vector control) or POLDIP3 plus ZsGreen as described in Materials and Methods. (B) Overexpression of POLDIP3 in IPEC-J2 cells.
Jianfei Chen (3186999)   +9 more
core   +1 more source

A20 restricted PDCoV release through negative regulation of PANoptosis. [PDF]

open access: yesmBio
ABSTRACT Coronavirus infections can trigger multiple modes of cell death, leading to severe infectious diseases. The process is modulated by host factors with mechanisms yet to be fully elucidated.
Lu C   +8 more
europepmc   +3 more sources

Susceptibility of Chickens to Porcine Deltacoronavirus Infection

open access: yesViruses, 2019
Porcine deltacoronavirus (PDCoV) is a novel swine enteropathogenic coronavirus with worldwide distribution. PDCoV belongs to the Deltacoronavirus (DCoV) genus, which mainly includes avian coronaviruses (CoVs).
Qingqing Liang   +8 more
doaj   +1 more source

Development of a Novel Double Antibody Sandwich ELISA for Quantitative Detection of Porcine Deltacoronavirus Antigen

open access: yesViruses, 2021
Porcine deltacoronavirus (PDCoV) can cause diarrhea and dehydration in newborn piglets. Here, we developed a double antibody sandwich quantitative enzyme-linked immunosorbent assay (DAS-ELISA) for detection of PDCoV by using a specific monoclonal ...
Wei Wang   +9 more
doaj   +1 more source

Pathogenicity of porcine deltacoronavirus (PDCoV) strain NH and immunization of pregnant sows with an inactivated PDCoV vaccine protects 5‐day‐old neonatal piglets from virulent challenge [PDF]

open access: yesTransboundary and Emerging Diseases, 2019
In this study, the pathogenicity of porcine deltacoronavirus (PDCoV) strain NH (passage 10, P10) was evaluated. We found that PDCoV strain NH is enteropathogenic in 5-day-old pigs. Pathogenicity experiments provided a challenge model for studying the protection efficiency of passive immunity.
Jialin Zhang   +11 more
openaire   +2 more sources

Porcine deltacoronavirus (PDCoV) modulates calcium influx to favor viral replication

open access: yesVirology, 2020
Ionic calcium (Ca2+) is a versatile intracellular second messenger that plays important roles in cellular physiological and pathological processes. Porcine deltacoronavirus (PDCoV) is an emerging enteropathogenic coronavirus that causes serious vomiting and diarrhea in suckling piglets.
Bai, Dongcheng   +7 more
openaire   +2 more sources

Development and application of a low-priced duplex quantitative PCR assay based on SYBR Green I for the simultaneous detection of porcine deltacoronavirus and porcine sapelovirus

open access: yesVeterinární Medicína, 2023
Porcine deltacoronavirus (PDCoV) and porcine sapelovirus (PSV) are two viruses that can cause diarrhoea in pigs and bring great economic loss to the pig industry.
SJ Lu   +8 more
doaj   +1 more source

PDCoV infection results in a reduction of endogenous POLDIP3 in vivo.

open access: yes, 2023
(A) histological lesions by H&E staining. Original magnification, ×400. (B) Identification of PDCoV infection. Representative samples of jejunum and ileum were collected and subjected to the detection of PDCoV N mRNA by RT-qPCR.
Jianfei Chen (3186999)   +9 more
core   +1 more source

Porcine Deltacoronavirus-like Particles Produced by a Single Recombinant Baculovirus Elicit Virus-Specific Immune Responses in Mice

open access: yesViruses, 2023
Porcine deltacoronavirus (PDCoV) causes diarrhea and vomiting in neonatal piglets worldwide and has the potential for cross-species transmission. Therefore, virus-like particles (VLPs) are promising vaccine candidates because of their safety and strong ...
Yangkun Liu   +4 more
doaj   +1 more source

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