Results 41 to 50 of about 2,405 (181)
AbstractThe emergence and rapid spread of the acute respiratory syndrome coronavirus-2 have confirmed that animal coronaviruses represent a potential zoonotic source. Porcine deltacoronavirus is a worldwide evolving enteropathogen of swine, detected first in Hong Kong, China, before its global identification.
Amina Nawal Bahoussi +5 more
openaire +3 more sources
Overexpression of POLDIP3 inhibits PDCoV replication in IPEC-J2 cells.
(A) IPEC-J2 cells were transduced with a bicistronic lentivirus vector expressing ZsGreen alone (vector control) or POLDIP3 plus ZsGreen as described in Materials and Methods. (B) Overexpression of POLDIP3 in IPEC-J2 cells.
Jianfei Chen (3186999) +9 more
core +1 more source
A20 restricted PDCoV release through negative regulation of PANoptosis. [PDF]
ABSTRACT Coronavirus infections can trigger multiple modes of cell death, leading to severe infectious diseases. The process is modulated by host factors with mechanisms yet to be fully elucidated.
Lu C +8 more
europepmc +3 more sources
Susceptibility of Chickens to Porcine Deltacoronavirus Infection
Porcine deltacoronavirus (PDCoV) is a novel swine enteropathogenic coronavirus with worldwide distribution. PDCoV belongs to the Deltacoronavirus (DCoV) genus, which mainly includes avian coronaviruses (CoVs).
Qingqing Liang +8 more
doaj +1 more source
Porcine deltacoronavirus (PDCoV) can cause diarrhea and dehydration in newborn piglets. Here, we developed a double antibody sandwich quantitative enzyme-linked immunosorbent assay (DAS-ELISA) for detection of PDCoV by using a specific monoclonal ...
Wei Wang +9 more
doaj +1 more source
Pathogenicity of porcine deltacoronavirus (PDCoV) strain NH and immunization of pregnant sows with an inactivated PDCoV vaccine protects 5‐day‐old neonatal piglets from virulent challenge [PDF]
In this study, the pathogenicity of porcine deltacoronavirus (PDCoV) strain NH (passage 10, P10) was evaluated. We found that PDCoV strain NH is enteropathogenic in 5-day-old pigs. Pathogenicity experiments provided a challenge model for studying the protection efficiency of passive immunity.
Jialin Zhang +11 more
openaire +2 more sources
Porcine deltacoronavirus (PDCoV) modulates calcium influx to favor viral replication
Ionic calcium (Ca2+) is a versatile intracellular second messenger that plays important roles in cellular physiological and pathological processes. Porcine deltacoronavirus (PDCoV) is an emerging enteropathogenic coronavirus that causes serious vomiting and diarrhea in suckling piglets.
Bai, Dongcheng +7 more
openaire +2 more sources
Porcine deltacoronavirus (PDCoV) and porcine sapelovirus (PSV) are two viruses that can cause diarrhoea in pigs and bring great economic loss to the pig industry.
SJ Lu +8 more
doaj +1 more source
PDCoV infection results in a reduction of endogenous POLDIP3 in vivo.
(A) histological lesions by H&E staining. Original magnification, ×400. (B) Identification of PDCoV infection. Representative samples of jejunum and ileum were collected and subjected to the detection of PDCoV N mRNA by RT-qPCR.
Jianfei Chen (3186999) +9 more
core +1 more source
Porcine deltacoronavirus (PDCoV) causes diarrhea and vomiting in neonatal piglets worldwide and has the potential for cross-species transmission. Therefore, virus-like particles (VLPs) are promising vaccine candidates because of their safety and strong ...
Yangkun Liu +4 more
doaj +1 more source

