Results 91 to 100 of about 12,266 (204)

Safety and efficacy of Rezūm water vapour energy therapy in BPH patients receiving antithrombotic therapy: A Japanese single‐centre experience

BJUI Compass, Volume 7, Issue 2, February 2026.
Abstract Objectives The objective of this study is to evaluate the safety and efficacy of Rezūm water vapour energy therapy (WAVE) in Japanese patients with benign prostatic hyperplasia (BPH) continuing antithrombotic therapy and to validate the Okayama University Modified Clavien‐Dindo classification (OU‐mCD) for perioperative hematuria.
Takatoshi Moriwake, Yusuke Tominaga, Satoshi Katayama, Haruki Kaku, Ichiro Tsuboi, Kasumi Yoshinaga, Tomoaki Yamanoi, Tatsushi Kawada, Takuya Sadahira, Takehiro Iwata, Shingo Nishimura, Kensuke Bekku, Yasuhiro Katayama, Motoo Araki   +13 more
wiley   +1 more source

Tadalafil once daily in the management of erectile dysfunction: patient and partner perspectives

Patient Preference and Adherence, 2009
Pierre Costa1, Thierry Grivel2, Naji Gehchan31Service d’Urologie–Andrologie, Hôpital Caremeau, Nîmes, France; 2159, Avenue Sainte-Marguerite, Nice, France; 3Eli Lilly and Company, Lilly France – Medical ...
Pierre Costa, Thierry Grivel, Naji Gehchan   +2 more
doaj  

Effects of tadalafil on urinary continence recovery after nerve-sparing robot-assisted radical prostatectomy

Медицинский совет, 2014
Phosphodiesterase type 5 (PDE5) inhibitors modulate afferent nerve activity, increase nitric oxide activity resulting in the corpus cavernosal smooth muscle relaxation in the penis, prostate, urethra and bladder neck.
AV Govorov, DY Pushkar, AO Vasilyev, DV Priymak   +3 more
doaj   +1 more source

Gonadal function in males with WFS1 spectrum disorder (Wolfram syndrome)—A European cohort perspective

Andrology, Volume 14, Issue 2, Page 398-410, February 2026.
Abstract Background WFS1 spectrum disorder, also known as Wolfram syndrome (WS) is an ultra‐rare (<1:500,000; ORPHA: 3463) monogenic (OMIM #222300) progressive neuroendocrine and neurodegenerative disorder, characterised by early‐onset insulin‐dependent diabetes, optic atrophy, central diabetes insipidus and sensi‐neuronal deafness.
Julia Rohayem, Olivia Cunningham, Denise Williams, Joachim Wistuba, Liam McCarthy, Timothy G. Barrett, Renuka P. Dias   +6 more
wiley   +1 more source

Regulation of the G2/M Transition in Rodent Oocytes [PDF]

, 2010
Regulation of maturation in meiotically competent mammalian oocytes is a complex process involving the carefully coordinated exchange of signals between the somatic and germ cell compartments of the ovarian follicle via paracrine and cell–cell coupling ...
Downs, Stephen
core   +2 more sources

Pharmacokinetics, pharmacodynamics, and safety interaction study of tunodafil hydrochloride and alcohol: A randomized, blinded, placebo‐controlled, three‐cycle crossover study in Chinese healthy men

Andrology, Volume 14, Issue 2, Page 466-479, February 2026.
Abstract Objectives This study aimed to evaluate the pharmacodynamic effects of administering tunodafil hydrochloride with alcohol on blood pressure and heart rate in healthy Chinese males, and to investigate the mutual pharmacokinetic interactions and safety of the combination.
Dingyuan Hu, Suping Niu, Fan Huang, Lu Jin, Qun Gu, Yanting Li, Chongyou Lee, Zhenwei Xie, Xiangxing Liu, Fang Men, Wenyan Zhao, Shuang Li, Yian Liu, Qian Wang, Huaying Fan, Jiaojiao Zhang, Shuangshuang Lin, Liming Chen, Yi Fang   +18 more
wiley   +1 more source

Repurposing of phosphodiesterase-5 inhibitor sildenafil as a therapeutic agent to prevent gastric cancer growth through suppressing c-MYC stability for IL-6 transcription

Communications Biology
Phosphodiesterase-5 (PDE5) inhibitors have shown promise as anti-cancer agents in malignancies. However, their specific effects on gastric cancer (GC) and the underlying mechanisms remain elusive.
Zhenzhan Zhang, Wuqing Huang, Donghua Huang, Zhou Xu, Qingfeng Xie, Xin Tan, Wenjun He, Weihao Yang, Guoxin Li, Jianguang Ji, Hao Liu   +10 more
doaj   +1 more source

Transient hypercapnia reveals an underlying cerebrovascular pathology in a murine model for HIV-1 associated neuroinflammation: role of NO-cGMP signaling and normalization by inhibition of cyclic nucleotide phosphodiesterase-5 [PDF]

, 2012
Cerebral blood flow (CBF) is known to be dysregulated in persons with human immunodeficiency virus 1 (HIV-1), for uncertain reasons. This is an important issue because impaired vasoreactivity has been associated with increased risk of ischemic stroke ...
Dewhurst, Stephen, Feng, Changyong, Granger, Megan, Kasischke, Karl A, Knight, Walter, Lopez, Tenée, Ontiveros, Fernando, Polesskaya, Oksana, Silva, Jharon, Ting Zheng, Johnny, Yan, Chen   +10 more
core   +2 more sources

Type 5 Phosphodiesterase Inhibition in Heart Failure The Next Step⁎⁎Editorials published in the Journal of the American College of Cardiologyreflect the views of the authors and do not necessarily represent the views of JACCor the American College of Cardiology. [PDF]

, 2005
Newsletter for Boston University School of Medicine ...
BUSM Alumni Association, Grande, Donald J., Levin, Sharon, Manuel, Barry M., Oates, Elizabeth   +4 more
core   +1 more source

Combination of Vacuum Erection Device and PDE5 Inhibitors as Salvage Therapy in PDE5 Inhibitor Nonresponders with Erectile Dysfunction

The Journal of Sexual Medicine, 2009
ABSTRACT Introduction Oral phosphodiesterase type 5 inhibitors (PDE5i) have improved treatment options for erectile dysfunction (ED). In case of unresponsiveness to PDE5i, alternative therapies are considered.
Onder, Canguven, James, Bailen, William, Fredriksson, David, Bock, Arthur L, Burnett   +4 more
openaire   +2 more sources