Results 101 to 110 of about 1,269,816 (226)

Positive modulation of glucagon‐like peptide 1 (GLP‐1) receptor by endogenous haemorphins with implications in glucose metabolism and diabetes

British Journal of Pharmacology, EarlyView.
Haemorphins act on GLP‐1 receptor (GLP‐1R) activity and signalling in a positive allosteric manner. This leads to potentiated GLP‐1‐mediated activity and signalling, as well as insulin synthesis, which may have implications for glucose metabolism and, thereby, diabetes and obesity. (The graph was created in BioRender.com).
Farheen Badrealam Khan, Rwdah Mohamed Alameri, Yasir S. Raouf, Damien Maurel, Naiem Ahmad Wani, Anatoliy Shmygol, Irfa Anwar, Heng B. See, Elizabeth K. M. Johnstone, Elodie Dupuis, Eric Trinquet, Kevin D. G. Pfleger, Emilia Oueis, Mohammed Akli Ayoub   +13 more
wiley   +1 more source

Project: PRJEB62784

1 File script with command for downland all files (189, 55 Gb, JSON -90- and TSV -90-) using WGET.Improving peach cultivars with superior traits is a primary objective of breeding initiatives. In this study, we aimed to elucidate the genetic basis of key
CSIC - Estación Experimental de Aula Dei (EEAD)
core   +1 more source

Inhibition of the MER tyrosine kinase ameliorates pulmonary fibrosis by suppressing macrophage M2 polarisation and osteopontin signalling

British Journal of Pharmacology, EarlyView.
Background and Purpose The MER proto‐oncogene tyrosine kinase (MERTK) has been implicated in the pathogenesis of pulmonary fibrosis (PF), and MERTK inhibition has been shown to ameliorate PF. However, the mechanisms remain unclear. Here, we have investigated how MERTK inhibition attenuates bleomycin (BLM)‐induced PF in mice and to elucidate the ...
Juan Li, Xiangsheng Yang, Xiao Xiao Tang
wiley   +1 more source

Effects of lifelong sulforaphane intake on behavioural, neurochemical and biomolecular dysfunctions in the BTBR T+ Itpr3tf/J mouse model of autism spectrum disorders

British Journal of Pharmacology, EarlyView.
Created in BioRender. Schiavone, S. (2026). https://BioRender.com/cy0xq6z. Abstract Background and Purpose Autism spectrum disorders (ASD) are multifactorial neurodevelopmental conditions associated with oxidative stress and neuroinflammation across critical developmental periods.
Vladyslav Sikora, Maria Bove, Lisa Pia Agosti, Rossella Pia Palmieri, Mohsin Zafar, Paolo Tucci, Maria Grazia Morgese, Stefania Schiavone, Luigia Trabace   +8 more
wiley   +1 more source

Interlaboratory Validation of High-Throughput Sequencing for the Detection of Viruses and Viroids in Apple, Grapevine, and Stone Fruits

PhytoFrontiers
High-throughput sequencing (HTS) has been demonstrated to be a paradigm shift for post-entry quarantine programs by increasing their ability to detect unknown plant viruses that have remained undetected by conventional diagnostic tools.
Peter Abrahamian, Weili Cai, Schyler O. Nunziata, Kristian Stevens, Xiaojun Hu, Min Sook Hwang, Larissa C. Costa, Charles A. Belanger, Benjamin Atha, Yu Yang, Nourolah Soltani, Oscar P. Hurtado-Gonzales, Maher Al Rwahnih, Yazmín Rivera   +13 more
doaj   +1 more source

Peach Family on Wagon Trip to the Grand Canyon

The Peach family on a wagon trip.

core  

Un/Learning Adult Frames of Reference in Death Enquiries: Thinking~With a Picturebook, Philosophical Animism and Ontological Tact

Children &Society, EarlyView.
ABSTRACT Developmental psychology continues to shape how adults engage with children about death and dying. This influences whether children are included in rituals surrounding human and other‐than‐human bodies. Figurations of the innocent, immature and vulnerable child still dominate adult imaginaries of young children's understandings of mortality ...
Karin Murris, Joanna Haynes, Joanne Peers   +2 more
wiley   +1 more source

Extreme site fidelity in long‐distance migratory shorebirds in Australia and potential implications for conservation

Conservation Biology, EarlyView.
Abstract Site fidelity is the tendency for animals to repeatedly return to the same locations, either within or between years. Site fidelity enables animals to utilize knowledge of previously visited locations, including assessments of seasonal variations in health and mortality risks (e.g., predation), resource availability, and social benefits such ...
Tobias A. Ross, Australasian Wader Studies Group, Victorian Wader Study Group, Queensland Wader Study Group, Robyn Atkinson, Maureen Christie, Danny I. Rogers, Chris Hassell, Roz Jessop, Jonathan T. Coleman, Theunis Piersma, Sara Ryding, Aaron Spence, Marcel Klaassen   +13 more
wiley   +1 more source

Toward a minimal amino acid alphabet for protein design

The FEBS Journal, EarlyView.
Proteins are built from 20 canonical amino acids; however, it is interesting to investigate whether they can also be formed from reduced amino acid alphabets. Using protein design, we designed proteins based on all alphabets comprising 2 to 10 ‘early’ amino acids (those likely to have been present before the origin of life).
Karel Půbal, Kseniia Kushnir, Vojtěch Spiwok, Karolína Loužecká, Vladimír Setnička, Petra Lipovová   +5 more
wiley   +1 more source

Peach Twig Borer (Anarsia lineatella) [PDF]

, 2019
This fact sheet describes the peach twig borer, a major pest of apricot and peach/nectarine in ...
Alston, Diane G., Murray, Marion
core   +1 more source