Results 11 to 20 of about 217,788 (200)

Recombinant peanut allergen Ara h I expression and IgE binding in patients with peanut hypersensitivity. [PDF]

Journal of Clinical Investigation, 1995
Peanut allergy is a significant health problem because of the frequency, the potential severity, and the chronicity of the allergic sensitivity. Serum IgE from patients with documented peanut hypersensitivity reactions and a peanut cDNA expression library were used to identify clones that encode peanut allergens.
A Wesley Burks, Gael Cockrell, J Steven Stanley   +2 more
exaly   +5 more sources

Recent advances in understanding and preventing peanut and tree nut hypersensitivity [version 1; referees: 2 approved] [PDF]

F1000Research, 2018
Peanut allergy, the most persistent and deadly of the food allergies, has become more prevalent worldwide in recent decades. Numerous explanations have been offered for the rise in peanut allergy, which has been more pronounced in Western, industrialized
Ayan Kusari, Allison Han, Lawrence Eichenfield   +2 more
doaj   +8 more sources

Immunotherapy Effectiveness in Treating Peanut Hypersensitivity: A Systemic Review. [PDF]

Cureus, 2022
Peanut hypersensitivity is one of the top causes of food-related allergic responses and death in high-income countries. As a result, the goal of this study was to see if various forms of immunotherapies can help reduce the severity of peanut hypersensitivity reactions.
Alghamdi R, Alshaier R, Alotaibi A, Almutairi A, Alotaibi G, Faqeeh A, Almalki A, AbdulMajed H.   +7 more
europepmc   +5 more sources

Development and evaluation of mouse anti-Ara h 1 and Ara h 3 IgE monoclonal antibodies for advancing peanut allergy research

MethodsX, 2023
Immediate hypersensitivity reactions to peanuts are a considerable public health concern due to the acute and severe IgE mediated reactions. To conduct research on the pathogenesis and therapeutics of peanut allergies, it is imperative to have mouse anti-
Takaki Waritani, Sidney Lomax, Dawn Cutler, Jessica Chang   +3 more
doaj   +3 more sources

Diacylglycerol kinase ζ deficiency in a non-CD4+ T-cell compartment leads to increased peanut hypersensitivity [PDF]

Journal of Allergy and Clinical Immunology, 2011
Peanut sensitization in diacylglycerol kinase zeta (DGKζ) deficient mice led to elevated peanut-IgE levels and severe anaphylaxis. DGKζ deficient CD4+T cells did not account for the phenotype. Future studies will determine which immune lineage caused increased food hypersensitivity.
Mike Kūlis, Balachandra K Gorentla, A Wesley Burks   +2 more
exaly   +4 more sources

Therapeutic effects of a fermented soy product on peanut hypersensitivity is associated with modulation of T‐helper type 1 and T‐helper type 2 responses [PDF]

Clinical and Experimental Allergy, 2008
SummaryBackground ImmuBalance™ is a koji fungus (Aspergillus oryzae) and lactic acid fermented soybean product. This unique production process is believed to create a food supplement that helps to induce or maintain normal immune response.Objective To assess possible therapeutic effects of ImmuBalance™ on peanut (PN) hypersensitivity using ...
B Schofield, Hugh A Sampson, Xiu-Min Li   +2 more
exaly   +4 more sources

Targeting Ara h 2 with human‐derived monoclonal antibodies prevents peanut‐induced anaphylaxis in mice [PDF]

Allergy. European Journal of Allergy and Clinical Immunology, 2023
Peanut allergy is a type‐I hypersensitivity immune reaction mediated by the binding of peanut allergens to IgE‐FcεRI complexes on mast cells and basophils and by their subsequent cellular degranulation.
M. Paolucci, Natascha Wuillemin, Valentine Homère, Dimitri Bieli, Alice Köhli, B. Ballmer-Weber, Y. Waeckerle‐Men, N. Pengo, T. Kündig, Tiziana Sonati, P. Johansen   +10 more
semanticscholar   +2 more sources

A lurking threat: transfer of peanut allergy through peripheral blood stem cell transplantation

World Allergy Organization Journal, 2016
Background There exist several reports of atopy and allergen-specific IgE-mediated hypersensitivity transferred by bone marrow transplantation, and it has been concluded that the transfer of allergic reactivity results from adoptive transfer of IgE ...
Birka Brauns, Michael P. Schön, Gerald Wulf, Martin Mempel   +3 more
doaj   +2 more sources

Diagnostic Value of In Vitro Tests for Peanut Allergy in Children Without Clinical Exposure: A High-Specificity Rule-In Decision Pathway—Preliminary Findings from a Single-Center Study in Polish Children [PDF]

Children
Background: Diagnosing peanut allergy (PA) in children without known exposure remains challenging due to the need to distinguish true clinical allergy from asymptomatic sensitization.
Julia Tworowska, Kinga Lis, Zbigniew Bartuzi, Aneta Krogulska   +3 more
doaj   +2 more sources

Natural history of perceived food hypersensitivity and IgE sensitisation to food allergens in a cohort of adults. [PDF]

PLoS ONE, 2014
BACKGROUND: No longitudinal studies exist on the natural history of food hypersensitivity and IgE sensitisation to food allergens in adults. OBJECTIVE: To examine the natural history of food hypersensitivity, the natural history of IgE sensitisation to ...
Antonios Patelis, Maria Gunnbjörnsdottir, Magnus P Borres, Peter Burney, Thorarinn Gislason, Kjell Torén, Bertil Forsberg, Kjell Alving, Andrei Malinovschi, Christer Janson   +9 more
doaj   +3 more sources