Results 21 to 30 of about 217,788 (200)

Genetic Determinants of Peanut-Specific IgG4 Levels in the Context of Sustained Oral Peanut Exposure in the LEAP Study. [PDF]

Immunology
A cumulative genetic score based on IgG4‐associated variants explains a substantial proportion of variance in psIgG4 levels during sustained peanut consumption, highlighting strong gene‐by‐environment interactions. Our findings suggest that early, sustained peanut consumption, in combination with genetic factors, promotes a protective immune response ...
Kanchan K, Cerosaletti K, Perry JA, DuToit G, Manohar M, Ling H, Paschall JE, Sanda S, Chinthrajah RS, Nepom GT, Nadeau KC, Jones SM, Lack G, Ruczinski I, Mathias RA.   +14 more
europepmc   +2 more sources

Strain matters in mouse models of peanut‐allergic anaphylaxis: Systemic IgE‐dependent and Ara h 2‐dominant sensitization in C3H mice

Clinical and Experimental Allergy, 2023
Peanut allergy accounts for the majority of food‐induced hypersensitivity reactions and can lead to lethal anaphylaxis. Animal models can provide an insight into the immune mechanisms responsible for sensitization and allergic anaphylaxis.
M. Paolucci, Valentine Homère, Y. Waeckerle‐Men, Natascha Wuillemin, Dimitri Bieli, N. Pengo, Tiziana Sonati, T. Kündig, P. Johansen   +8 more
semanticscholar   +2 more sources

Effect of Epicutaneous Immunotherapy vs Placebo on Reaction to Peanut Protein Ingestion Among Children With Peanut Allergy: The PEPITES Randomized Clinical Trial

Journal of the American Medical Association (JAMA), 2019
Importance There are currently no approved treatments for peanut allergy. Objective To assess the efficacy and adverse events of epicutaneous immunotherapy with a peanut patch among peanut-allergic children.
D. Fleischer, M. Greenhawt, G. Sussman, P. Bégin, A. Nowak‐Wegrzyn, D. Petroni, K. Beyer, T. Brown-Whitehorn, J. Hébert, J. Hourihane, D. Campbell, S. Leonard, R. Chinthrajah, J. Pongracic, S. Jones, L. Lange, H. Chong, Todd D. Green, Todd D. Green, R. Wood, A. Cheema, S. Prescott, Peter Smith, William H. Yang, E. Chan, A. Byrne, A. Assa'ad, J. Bird, Edwin H. Kim, L. Schneider, C. Davis, B. Lanser, R. Lambert, W. Shreffler   +33 more
semanticscholar   +2 more sources

Sensitization to storage proteins in peanut and hazelnut is associated with higher levels of inflammatory markers in asthma

Clinical and Molecular Allergy, 2020
Background Sensitization to peanuts and hazelnuts is common among young asthmatics and can be primary or a result of cross-reactivity. Sensitization as a result of cross-reactivity to birch pollen is typically associated to tolerance or mild and local ...
Jennifer Johnson, A. Malinovschi, J. Lidholm, C. Petersson, L. Nordvall, C. Janson, K. Alving, M. Borres   +7 more
semanticscholar   +2 more sources

Cutaneous Exposure to Peanut Oil Induces Systemic and Pulmonary Peanut Hypersensitivity Reaction [PDF]

Journal of Allergy and Clinical Immunology, 2018
Shira Benor, Laliv Kadar, Shmuel Kivity, Sheila Langier   +3 more
openaire   +2 more sources

Antiallergic activity of Lactobacillus plantarum against peanut allergy in a Balb/c mouse model

Food and Agricultural Immunology, 2019
Antiallergic activities of Lactobacillus plantarum (L. plantarum) prepared from kimchi as orally administered probiotics were examined in type I peanut allergy mice models. Oral administration with L.
Xin Yang, Ye Liu, Xiaodan Guo, Qiao Bai, Xiaofan Zhu, Hong Ren, Qiwen Chen, Tianli Yue, Fangyu Long   +8 more
doaj   +2 more sources

Exploring the Landscape of Food Allergies in Pediatric Atopic Dermatitis: A Cross-Sectional Study in Iran

Indian Journal of Dermatology
Background: The prevalence of food allergy (FA) in Iranian children with atopic dermatitis (AD) is unknown. This study aims to determine the prevalence and kind of FA in Iranian children with AD.
Mohadese Mahdavi, Saber Gharagozlou, Masoud Movahedi, Nima Parvaneh, Arash Kalantari, Mohadese Sadat Mousavi Khorshidi, Mehdi Shokri, Fatemeh Alizadeh, Mahshid Movahedi, Mohammad Gharagozlou   +9 more
doaj   +2 more sources

Development of a mini pig model of peanut allergy

Frontiers in Allergy
IntroductionThe prevalence of peanut allergies is increasing, emphasizing the need for an animal model to enhance our understanding of peanut allergy pathogenesis and to advance diagnostic tools and therapeutic interventions.
Akhilesh Kumar Shakya, Brittany Backus, Lazar D. Nesovic, Malini Mallick, Olivia Banister, Carla M. Davis, Sara Anvari, Harvinder Singh Gill   +7 more
doaj   +3 more sources

Adjuvant activity of peanut, cottonseed and rice oils on cellular and humoral response

VacciMonitor, 2013
The potentiality of the usage of vegetable oils such as soybean, corn, olive, sesame, murici seed, rapeseed, linseed, rice and cashew nuts as adjuvant of the humoral and cellular immune response has been recently shown.
Erika Freitas, Ana Claudia Marinho, Deijanira Albuquerque, Leiliane Teles, Mércia Sindeaux, María Teresa Salles, Diana Célia Sousa, Margarida María Lima, María da Guia Silva, Dirce Fernandes   +9 more
doaj   +1 more source

Induction of allergic responses to peanut allergen in sheep. [PDF]

PLoS ONE, 2012
Peanut allergy is the leading cause of deaths due to food-induced anaphylaxis but despite continued research, there are currently no specific treatments available.
Jenna L Van Gramberg, Michael J de Veer, Robyn E O'Hehir, Els N T Meeusen, Robert J Bischof   +4 more
doaj   +1 more source