Results 41 to 50 of about 8,404 (128)
Emerging Paediatric Uses of Dupilumab Beyond Approvals
Dupilumab, through IL‐4Rα blockade, shows promising efficacy beyond approved indications in paediatric diseases driven by T2 inflammation. Emerging evidence—mainly from small studies—supports improvements in disease severity and quality of life, highlighting its potential as a targeted, steroid‐sparing therapy while underscoring the need for ...
Simone Foti Randazzese +11 more
wiley +1 more source
RECURRENT APHTHOUS STOMATITIS RELATED TO PSYCHOLOGICAL STRESS, FOOD ALLERGY AND GERD
Background: Recurrent Aphthous Stomatitis (RAS) is inflammation in oral mucosa characterized by recurrent single or multiple ulcers that usually affected in non keratinized mucosa.
Rina Kartika Sari +2 more
doaj +1 more source
Edible Insect Allergens: An Emerging Food Safety Challenge
Allergic responses to edible insects arise via two main pathways: cross‐reactivity with homologous arthropod allergens and primary sensitization to edible insect proteins, both leading to IgE‐mediated immune activation. ABSTRACT Edible insects are increasingly promoted as sustainable protein sources; however, their allergenic potential remains a ...
Changqi Liu +5 more
wiley +1 more source
Gamma Delta T Cells in Shrimp Allergy Express a Unique Cytotoxic Cytokine Profile
ABSTRACT Shellfish allergy is the most common food allergy in adults and the third most common in children. γδ T cells have been identified as playing a critical role in antigen tolerance in allergic diseases in mouse models. In humans, γδ T cells may play a regulatory role in peanut immunotherapy, and their role in shrimp allergy remains unclear.
Brenda Bin Su +9 more
wiley +1 more source
It's bean too long: Interventions to reintroduce legumes to the UK palate and plate
Increased legume consumption can offer considerable health and sustainability benefits. Legume intake in the UK is low, and a number of barriers to intake have been identified. Adopting the Nuffield Council on Bioethics Intervention Ladder, we identify and review an array of interventions—with increasing levels of intervening—that could support ...
Neil Bernard Boyle +7 more
wiley +1 more source
Peanut Allergy in Mexican Children: What Is the Effect of Age at First Consumption?
Studies suggest that children who start solid foods early are at risk for developing food allergies. Herein, we evaluated the effects of the introduction of peanuts to the diets of children on emerging peanut allergies.
Martín Bedolla Barajas +4 more
doaj
Hypersensitivity to Excipients in Drugs: An EAACI Position Paper
ABSTRACT Drugs contain active pharmaceutical ingredients and excipients, compounds which enhance the pharmacokinetics, stability and palatability of the pharmaceutical formulation. While most drug hypersensitivity reactions (DHR) are caused by active ingredients, excipients may also be involved.
Lene H. Garvey +10 more
wiley +1 more source
Global crotonylome profiling identifies TaPRXIIBK172 crotonylation as a key modification that modulates H2O2 homeostasis, reduces enzyme activity and enhances wheat resistance to leaf rust. ABSTRACT Wheat food security is severely threatened by Puccinia triticina infection.
Qipeng Wang +8 more
wiley +1 more source
近年来,花生过敏问题日益突出,已成为全球关注的公共卫生和食品安全问题之一。旨在为低敏性花生产品的研发提供理论依据,综述了花生致敏机制、主要过敏原及其抗原表位,并全面探讨了生物法降低花生致敏性的机制及研究进展。花生过敏是由IgE介导的Ⅰ类超敏反应。目前已鉴定出17种花生致敏原蛋白,其中Ara h 1、Ara h 2、Ara h 3和Ara h 6是主要过敏原,它们存在多种抗原表位。生物法脱敏包括酶法和发酵法,其中酶法脱敏包括酶解和酶交联两种方式 ...
李梦瑶,石松业,布冠好,陈屹轩,王卓宁,洪童心 LI Mengyao, SHI Songye, BU Guanhao, CHEN Yixuan, WANG Zhuoning, HONG Tongxin
doaj +1 more source
Gastrointestinal manifestations during oral immunotherapy: A guide for pediatric allergists
Gastrointestinal manifestations occurring during oral immunotherapy (OIT) encompass a spectrum of conditions ranging from immediate IgE‐mediated reactions to delayed eosinophil‐associated disorders, including eosinophilic esophagitis. Because symptoms may overlap with other gastrointestinal diseases, a structured assessment based on symptom timing ...
Martina Votto +11 more
wiley +1 more source

