Results 51 to 60 of about 3,169,769 (303)

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

FEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker, Swantje Kebel, Lea Völkening, Anna Vatselia, Louisa Weinhold, Girmay Asgedom, Axel Schambach, Detlev Schindler, Thilo Dörk, Kristine Bousset   +9 more
wiley   +1 more source

Pediatric Orthopaedic Clinical Peer-review Triggers and Ongoing Professional Practice Evaluation (OPPE) Metrics: An Ohio Statewide Consensus

Journal of the Pediatric Orthopaedic Society of North America
Background: Two critical mechanisms to measure competency in pediatric orthopaedic surgery are case-based clinical peer review and ongoing professional practice evaluation (OPPE). However, we currently lack a standard set of triggers or metrics to inform
Julie B. Samora, MD, PhD, Kevin Baker, RN, Kerwyn Jones, MD, Michael Vish, MD, Susan P. Tourner, MD, Michael Vossmeyer, MD, Nichole Liston, RN, Todd F. Ritzman, MD, Michael T. Bigham, MD, MBA   +8 more
doaj   +1 more source

Peer Feedback Tool for Lectures & Small-Group Teaching

MedEdPORTAL, 2011
This resource is a teaching assessment tool designed to provide faculty members with information about the quality of their teaching based on peer observation.
Maria Blanco, Carol Capello, Maryellen Gusic, Wayne McCormack, Janet Hafler   +4 more
doaj   +1 more source

A frustrated spin-1/2 Heisenberg antiferromagnet on a chevron-square lattice [PDF]

, 2013
The coupled cluster method (CCM) is used to study the zero-temperature properties of a frustrated spin-half ($s={1}{2}$) $J_{1}$--$J_{2}$ Heisenberg antiferromagnet (HAF) on a 2D chevron-square lattice.
Bishop, R. F., Campbell, C. E., Li, P. H. Y.   +2 more
core   +2 more sources

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

FEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia, Eric Catalina‐Hernandez, Maialen Cabrerizo‐Idiazabal, Ramon Barnadas‐Rodríguez, Mario Lopez‐Martin, Alex Peralvarez‐Marin   +5 more
wiley   +1 more source

Peer Comment

Internet Archaeology, 2015
Peer comment on Blogging the Field School: Teaching Digital Public Archaeology by Terry P. Brock and Lynne Goldstein.
Whitney Battle-Baptiste
doaj   +5 more sources

Maintaining Live Discussion in Two-Stage Open Peer Review

Frontiers in Computational Neuroscience, 2012
Open peer review has been proposed for a number of reasons, in particular, for increasing the transparency of the article selection process for a journal, and for obtaining a broader basis for feedback to the authors and for the acceptance decision.
Erik eSandewall, Erik eSandewall
doaj   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

Developing a cognitive conservation model for the management of Malaysian birders' behavior toward birds

Frontiers in Sustainable Tourism
IntroductionBirdwatching as a subcategory of ecotourism can create recreational disturbance. This research aims to assess two main goals: firstly, the effects of the frequency of participation (FOP) of Malaysian birders as moderators on the constructs of
Marjan Jafarpour, Haywantee Ramkissoon, Haywantee Ramkissoon, Haywantee Ramkissoon, Haywantee Ramkissoon   +4 more
doaj   +1 more source